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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Cyclooxygenase-1 signaling is required for vascular tube formation during development

Authors:
Cha YI, Kim SH, Solnica-Krezel L, Dubois RN
Citation:
Dev Biol. 2005 Jun 1;282(1):274-83
Epub:
Not Epub
Abstract:
Prostaglandin endoperoxide synthases (PTGS), commonly referred to as cyclooxygenases (COX-1 and COX-2), catalyze the key step...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cha YI, Kim SH, Solnica-Krezel L, Dubois RN. Cyclooxygenase-1 signaling is required for vascular tube formation during development. Dev Biol. 2005 Jun 1;282(1):274-83.

Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation

Authors:
Cha YI, Kim SH, Sepich D, Buchanan FG, Solnica-Krezel L, DuBois RN
Citation:
Genes Dev. 2006 Jan 1;20(1):77-86
Epub:
Not Epub
Abstract:
Gastrulation is a fundamental process during embryogenesis that shapes proper body architecture and establishes three germ...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cha YI, Kim SH, Sepich D, Buchanan FG, Solnica-Krezel L, DuBois RN. Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes Dev. 2006 Jan 1;20(1):77-86.

Deep-intronic ATM mutation detected by genomic resequencing and corrected in vitro by antisense morpholino oligonucleotide (AMO)

Authors:
Cavalieri S, Pozzi E, Gatti R, Brusco A
Citation:
Eur J Hum Genet . 2012;[Epub ahead of print] /10.1038/ejhg.2012.266
Epub:
Not Epub
Abstract:
Recent development of next-generation DNA sequencing (NGS) techniques is changing the approach to search for mutations in human...
Organism or Cell Type:
cell culture: human primary lymphoblasts
Citation Extract:
Cavalieri S, Pozzi E, Gatti R, Brusco A. Deep-intronic ATM mutation detected by genomic resequencing and corrected in vitro by antisense morpholino oligonucleotide (AMO). Eur J Hum Genet . 2012;[Epub ahead of print] /10.1038/ejhg.2012.266.

Depletion of the cell-cycle inhibitor p27(Xic1) impairs neuronal differentiation and increases the number of ElrC(+) progenitor cells in Xenopus tropicalis

Authors:
Carruthers S, Mason J, Papalopulu N
Citation:
Mech Dev. 2003 May;120(5):607-16
Epub:
Not Epub
Abstract:
The Xenopus p27(Xic1) gene encodes a cyclin dependent kinase (CDK) inhibitor of the Cip/Kip family. We have previously shown...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Carruthers S, Mason J, Papalopulu N. Depletion of the cell-cycle inhibitor p27(Xic1) impairs neuronal differentiation and increases the number of ElrC(+) progenitor cells in Xenopus tropicalis. Mech Dev. 2003 May;120(5):607-16.

Dissection of angiogenic signaling in zebrafish using a chemical genetic approach

Authors:
Chan J, Bayliss PE, Wood JM, Roberts TM
Citation:
Cancer Cell. 2002. 1(3):257-267
Epub:
Not Epub
Abstract:
Striking homology between signaling molecules in zebrafish and humans suggests that compounds known to inhibit human kinases...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chan J, Bayliss PE, Wood JM, Roberts TM. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach. Cancer Cell. 2002. 1(3):257-267.

Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway

Authors:
Cavodeassi F, Carreira-Barbosa F, Young RM, Concha ML, Allende ML, Houart C, Tada M, Wilson SW
Citation:
Neuron. 2005 Jul 7;47(1):43-56
Epub:
Not Epub
Abstract:
During regional patterning of the anterior neural plate, a medially positioned domain of cells is specified to adopt retinal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cavodeassi F, Carreira-Barbosa F, Young RM, Concha ML, Allende ML, Houart C, Tada M, Wilson SW. Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway. Neuron. 2005 Jul 7;47(1):43-56.

Electroporation of DNA, RNA, and morpholinos into zebrafish embryos

Authors:
Cerda GA, Thomas JE, Allende ML, Karlstrom RO, Palma V
Citation:
Methods. 2006 Jul;39(3):207-11.
Epub:
Not Epub
Abstract:
The combination of accessible embryology and forward genetic techniques has made zebrafish a powerful model system for the...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Cerda GA, Thomas JE, Allende ML, Karlstrom RO, Palma V. Electroporation of DNA, RNA, and morpholinos into zebrafish embryos. Methods. 2006 Jul;39(3):207-11..

Eph/Ephrin signalling maintains eye field segregation from adjacent neural plate territories during forebrain morphogenesis

Authors:
Cavodeassi F, Ivanovitch K, Wilson SW
Citation:
Development. 2013 Oct;140(20):4193-4202. Epub 2013 Sep 11
Epub:
Not Epub
Abstract:
During forebrain morphogenesis, there is extensive reorganisation of the cells destined to form the eyes, telencephalon and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cavodeassi F, Ivanovitch K, Wilson SW. Eph/Ephrin signalling maintains eye field segregation from adjacent neural plate territories during forebrain morphogenesis. Development. 2013 Oct;140(20):4193-4202. Epub 2013 Sep 11.

ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles

Authors:
Chambon JP, Nakayama A, Takamura K, McDougall A, Satoh N
Citation:
Development. 2007 Mar;134(6):1203-19
Epub:
Not Epub
Abstract:
In ascidian tadpoles, metamorphosis is triggered by a polarized wave of apoptosis, via mechanisms that are largely unknown. We...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Chambon JP, Nakayama A, Takamura K, McDougall A, Satoh N. ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles. Development. 2007 Mar;134(6):1203-19.

Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent

Authors:
Cha HJ, Byrom M, Mead PE, Ellington AD, Wallingford JB, Marcotte EM
Citation:
PLoS Biol. 2012 Aug;10(8):e1001379. Epub 2012 Aug 21
Epub:
Not Epub
Abstract:
Studies in diverse organisms have revealed a surprising depth to the evolutionary conservation of genetic modules. For example...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cha HJ, Byrom M, Mead PE, Ellington AD, Wallingford JB, Marcotte EM. Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol. 2012 Aug;10(8):e1001379. Epub 2012 Aug 21.

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