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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure

Authors:
Brown JD, Dutta S, Bharti K, Bonner RF, Munson PJ, Dawid IB, Akhtar AL, Onojafe IF, Alur RP, Gross JM, Hejtmancik JF, Jiao X, Chan WY, Brooks BP
Citation:
Proc Natl Acad Sci U S A. 2009 Jan 26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The gene networks underlying closure of the optic fissure during vertebrate eye development are poorly understood. Here, we...
Organism or Cell Type:
zebrafish
Citation Extract:
Brown JD, Dutta S, Bharti K, Bonner RF, Munson PJ, Dawid IB, Akhtar AL, Onojafe IF, Alur RP, Gross JM, Hejtmancik JF, Jiao X, Chan WY, Brooks BP. Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure. Proc Natl Acad Sci U S A. 2009 Jan 26. [Epub ahead of print].

Frodo proteins: modulators of Wnt signaling in vertebrate development

Authors:
Brott BK, Sokol SY
Citation:
Differentiation. 2005 Sep;73(7):323-9
Epub:
Not Epub
Abstract:
The Frodo/dapper (Frd) proteins are recently discovered signaling adaptors, which functionally and physically interact with Wnt...
Delivery Method:
not published
Organism or Cell Type:
Xenopus
Citation Extract:
Brott BK, Sokol SY. Frodo proteins: modulators of Wnt signaling in vertebrate development. Differentiation. 2005 Sep;73(7):323-9.

Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia

Authors:
Butler R, Wood JD, Landers JA, Cunliffe VT
Citation:
Dis Model Mech. 2010 Sep 9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in the SPAST (SPG4) gene, which encodes the microtubule-severing protein spastin, are the most common cause of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Butler R, Wood JD, Landers JA, Cunliffe VT. Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia. Dis Model Mech. 2010 Sep 9. [Epub ahead of print].

Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development

Authors:
Cannon JE, Place ES, Eve AM, Bradshaw CR, Sesay A, Morrell NW, Smith JC
Citation:
Mech Dev. 2012 Oct 13. pii: S0925-4773(12)00108-6. doi: 10.1016/j.mod.2012.10.002. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In this paper we use zebrafish embryos to characterise the transcriptome of the developing blood and endothelium, two cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cannon JE, Place ES, Eve AM, Bradshaw CR, Sesay A, Morrell NW, Smith JC. Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development. Mech Dev. 2012 Oct 13. pii: S0925-4773(12)00108-6. doi: 10.1016/j.mod.2012.10.002. [Epub ahead of print].

Grk5l Controls Heart Development by Limiting mTOR Signaling during Symmetry Breaking

Authors:
Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M
Citation:
Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.07.036
Epub:
Not Epub
Abstract:
The correct asymmetric placement of inner organs is termed situs solitus and is determined early during development. Failure in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M. Grk5l Controls Heart Development by Limiting mTOR Signaling during Symmetry Breaking. Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.07.036.

Hematopoietic stem cell fate is established by the Notch-Runx pathway

Authors:
Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI
Citation:
Genes Dev. 2005 Oct 1;19(19):2331-42. Epub 2005 Sep 15.
Epub:
Not Epub
Abstract:
Identifying the molecular pathways regulating hematopoietic stem cell (HSC) specification, self-renewal, and expansion remains...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005 Oct 1;19(19):2331-42. Epub 2005 Sep 15..

Inhibition of vitellogenin gene induction by 2,3,7,8–tetrachlorodibenzo–p–dioxin is mediated by aryl hydrocarbon receptor 2 (AHR2) in zebrafish (Danio rerio)

Authors:
Bugel SM, White LA, Cooper KR
Citation:
Aquatic Toxicol. 2012;[Epub ahead of print] doi:10.1016/j.aquatox.2012.09.019
Epub:
Not Epub
Abstract:
Vitellogenins are hepatically derived yolk–protein precursors required for oogenesis in all oviparous teleosts. Altered gene–...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bugel SM, White LA, Cooper KR. Inhibition of vitellogenin gene induction by 2,3,7,8–tetrachlorodibenzo–p–dioxin is mediated by aryl hydrocarbon receptor 2 (AHR2) in zebrafish (Danio rerio). Aquatic Toxicol. 2012;[Epub ahead of print] doi:10.1016/j.aquatox.2012.09.019.

Integrins on eggs: the betaC subunit is essential for formation of the cortical actin cytoskeleton in sea urchin eggs

Authors:
Burke RD, Murray G, Rise M, Wang D
Citation:
Dev Biol. 2004 Jan 1;265(1):53-60
Epub:
Not Epub
Abstract:
Eggs of several metazoans have been demonstrated to express integrins; however, their function is unclear. Previous studies...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin
Citation Extract:
Burke RD, Murray G, Rise M, Wang D. Integrins on eggs: the betaC subunit is essential for formation of the cortical actin cytoskeleton in sea urchin eggs. Dev Biol. 2004 Jan 1;265(1):53-60.

Isolation of pigment cell specific genes in the sea urchin embryo by differential macroarray screening

Authors:
Calestani C, Rast JP, Davidson EH
Citation:
Development. 2003 Oct;130(19):4587-96
Epub:
Not Epub
Abstract:
New secondary mesenchyme specific genes, expressed exclusively in pigment cells, were isolated from sea urchin embryos using a...
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Calestani C, Rast JP, Davidson EH. Isolation of pigment cell specific genes in the sea urchin embryo by differential macroarray screening. Development. 2003 Oct;130(19):4587-96.

Lefty-dependent inhibition of nodal- and wnt-responsive organizer gene expression is essential for normal gastrulation

Authors:
Branford WW, Yost HJ
Citation:
Curr Biol. 2002 Dec 23;12(24):2136-41
Epub:
Not Epub
Abstract:
During gastrulation, diffusible \"organizer\" signals, including members of the TGFbeta Nodal subfamily, pattern...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Branford WW, Yost HJ. Lefty-dependent inhibition of nodal- and wnt-responsive organizer gene expression is essential for normal gastrulation. Curr Biol. 2002 Dec 23;12(24):2136-41.

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