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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
A male with unilateral microphthalmia reveals a role for TMX3 in eye development
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Citation:
PLoS One. 2010 May 11;5(5):e10565 Epub:
Not Epub Abstract:
Anophthalmia and microphthalmia are important birth defects, but their pathogenesis remains incompletely understood. We studied... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Chao R, Nevin L, Agarwal P, Riemer J, Bai X, Delaney A, Akana M, JimenezLopez N, Bardakjian T, Schneider A, Chassaing N, Schorderet DF, FitzPatrick D, Kwok PY, Ellgaard L, Gould DB, Zhang Y, Malicki J, Baier H, Slavotinek A. A male with unilateral microphthalmia reveals a role for TMX3 in eye development. PLoS One. 2010 May 11;5(5):e10565. |
An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis
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Citation:
Dev Biol. 2012 Apr 1;364(1):22-31. doi: 10.1016/j.ydbio.2012.01.011. Epub 2012 Jan 21. Epub:
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Mutations in ZIC3 result in X-linked heterotaxy in humans, a syndrome consisting of left–right (L–R) patterning defects,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish, Xenopus Citation Extract: Cast AE, Gao C, Amack JD, Ware SM. An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis. Dev Biol. 2012 Apr 1;364(1):22-31. doi: 10.1016/j.ydbio.2012.01.011. Epub 2012 Jan 21.. |
Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of VEGF-A expression and angiogenesis
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Citation:
J Biol Chem. 2012;[Epub ahead of print]doi:10.1074/jbc.M112.423871 Epub:
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HuR, also known as Elavl1, is an RNA binding protein that regulates embryonic development, progenitor cell survival and cell... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Chang SH, Lu YC, Li X, Hsieh WY, Xiong Y, Ghosh M, Evans T, Elemento O, Hla T. Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of VEGF-A expression and angiogenesis. J Biol Chem. 2012;[Epub ahead of print]doi:10.1074/jbc.M112.423871. |
Antagonistic interaction between IGF and Wnt/JNK signaling in convergent extension in Xenopus embryo
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Citation:
Mech Dev. 2005 Nov;122(11):1234-47. Epub 2005 Jul 18. Epub:
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The homeobox gene Otx2 is expressed during gastrulation in the anterior domain of the vertebrate embryo and is involved in... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Carron C, Bourdelas A, Li HY, Boucaut JC, Shi DL. Antagonistic interaction between IGF and Wnt/JNK signaling in convergent extension in Xenopus embryo. Mech Dev. 2005 Nov;122(11):1234-47. Epub 2005 Jul 18.. |
Anthrax toxin receptor 2a controls mitotic spindle positioning
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Citation:
Nat Cell Biol. 2013 Jan;15(1):28-39. doi: 10.1038/ncb2632. Epub 2012 Dec 2. Epub:
Not Epub Abstract:
Oriented mitosis is essential during tissue morphogenesis. The Wnt/planar cell polarity (Wnt/PCP) pathway orients mitosis in a... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Castanon I, Abrami L, Holtzer L, Heisenberg C, van der Goot FG, González-Gaitán M. Anthrax toxin receptor 2a controls mitotic spindle positioning. Nat Cell Biol. 2013 Jan;15(1):28-39. doi: 10.1038/ncb2632. Epub 2012 Dec 2.. |
aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development
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Citation:
Development. 2005 Mar;132(5):977-86. Epub 2005 Feb 2 Epub:
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In early vertebrate development, apicobasally polarised blastomeres divide to produce inner non-polarised cells and outer... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Chalmers AD, Pambos M, Mason J, Lang S, Wylie C, Papalopulu N. aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development. Development. 2005 Mar;132(5):977-86. Epub 2005 Feb 2. |
Ash1a and Neurogenin1 function downstream of Floating head to regulate epiphysial neurogenesis
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Citation:
Development 2003 Jun;130(11):2455-66 Epub:
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The homeodomain transcription factor Floating head (Flh) is required for the generation of neurones in the zebrafish epiphysis... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Cau E, Wilson SW. Ash1a and Neurogenin1 function downstream of Floating head to regulate epiphysial neurogenesis. Development 2003 Jun;130(11):2455-66. |
Calmodulin-dependent protein kinase gamma 3 (CamKIIgamma3) mediates the cell cycle resumption of metaphase II eggs in mouse
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Citation:
Development. 2009 Dec;136(24):4077-81. doi: 10.1242/dev.042143. Epub 2009 Nov 11. Epub:
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Mature mammalian eggs are ovulated arrested at meiotic metaphase II. Sperm break this arrest by an oscillatory Ca(2+) signal... Organism or Cell Type:
mouse oocytes Citation Extract: Chang HY, Minahan K, Merriman JA, Jones KT. Calmodulin-dependent protein kinase gamma 3 (CamKIIgamma3) mediates the cell cycle resumption of metaphase II eggs in mouse. Development. 2009 Dec;136(24):4077-81. doi: 10.1242/dev.042143. Epub 2009 Nov 11.. |
Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models
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Citation:
Proc Natl Acad Sci U S A. 2009;106(51):21819-24. doi:10.1073/pnas.0911987106 Epub:
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Polycystic kidney disease (PKD) is a common human genetic disease with severe medical consequences. Although it is appreciated... Organism or Cell Type:
zebrafish Citation Extract: Cao Y, Semanchik N, Lee SH, Somlo S, Barbano PE, Coifman R, Sun Z. Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models. Proc Natl Acad Sci U S A. 2009;106(51):21819-24. doi:10.1073/pnas.0911987106. |
CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors
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Citation:
Mol Cancer. 2009 Apr 16;8:24. doi: 10.1186/1476-4598-8-24. Epub:
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ABSTRACT: BACKGROUND: DNA repair deficient tumor cells have been shown to accumulate high levels of DNA damage. Consequently,... Organism or Cell Type:
zebrafish Citation Extract: Chen CC, Kennedy RD, Sidi S, Look AT, D'Andrea AD. CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors. Mol Cancer. 2009 Apr 16;8:24. doi: 10.1186/1476-4598-8-24.. |