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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12062 scientific papers returned from the database with the search filters currently being used below.

Novel antisense and peptide nucleic acid strategies for controlling gene expression

Authors:
Braasch DA, Corey DR
Citation:
Biochemistry 2002 Apr 9;41(14):4503-10
Epub:
Not Epub
Abstract:
Antisense oligonucleotides have the potential to make revolutionary contributions to basic science and medicine....
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Braasch DA, Corey DR. Novel antisense and peptide nucleic acid strategies for controlling gene expression. Biochemistry 2002 Apr 9;41(14):4503-10.

Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound

Authors:
Braun S, Hanselmann C, Gassmann MG, auf dem Keller U, Born-Berclaz C, Chan K, Kan YW, Werner S
Citation:
Mol Cell Biol. 2002 Aug;22(15):5492-505
Epub:
Not Epub
Abstract:
Keratinocyte growth factor (KGF) is a potent mitogen for epithelial cells, and it promotes survival of these cells under stress...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: mouse primary keratinocytes
Citation Extract:
Braun S, Hanselmann C, Gassmann MG, auf dem Keller U, Born-Berclaz C, Chan K, Kan YW, Werner S. Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol. 2002 Aug;22(15):5492-505.

Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window

Authors:
Canto-Soler MV, Adler R
Citation:
Dev Biol. 2006 2006 Jun 1;294(1):119-32. Epub 2006 Mar 27
Epub:
Not Epub
Abstract:
Pax6 mutations cause complex ocular malformations, but it is uncertain whether early eye development normally requires Pax6...
Delivery Method:
Injection then electroporation in vivo
Organism or Cell Type:
chick embryo
Citation Extract:
Canto-Soler MV, Adler R. Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window. Dev Biol. 2006 2006 Jun 1;294(1):119-32. Epub 2006 Mar 27.

Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos

Authors:
Buffone MG, Schindler K, Schultz RM
Citation:
Cell Cycle. 2009 Dec;8(23):3904-13. Epub 2009 Dec 14
Epub:
Not Epub
Abstract:
Following fertilization the transition from a highly differentiated oocyte to a totipotent 2-cell embryo requires two unique...
Delivery Method:
Microinjection
Organism or Cell Type:
Mouse embryo
Citation Extract:
Buffone MG, Schindler K, Schultz RM. Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos. Cell Cycle. 2009 Dec;8(23):3904-13. Epub 2009 Dec 14.

pak2a mutations cause cerebral hemorrhage in redhead zebrafish

Authors:
Buchner DA, Su F, Yamaoka JS, Kamei M, Shavit JA, Barthel LK, McGee B, Amigo JD, Kim S, Hanosh AW, Jagadeeswaran P, Goldman D, Lawson ND, Raymond PA, Weinstein BM, Ginsburg D, Lyons SE
Citation:
Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):13996-4001. Epub 2007 Aug 22
Epub:
Not Epub
Abstract:
The zebrafish is a powerful model for studying vascular development, demonstrating remarkable conservation of this process with...
Organism or Cell Type:
zebrafish
Citation Extract:
Buchner DA, Su F, Yamaoka JS, Kamei M, Shavit JA, Barthel LK, McGee B, Amigo JD, Kim S, Hanosh AW, Jagadeeswaran P, Goldman D, Lawson ND, Raymond PA, Weinstein BM, Ginsburg D, Lyons SE. pak2a mutations cause cerebral hemorrhage in redhead zebrafish. Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):13996-4001. Epub 2007 Aug 22.

Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation

Authors:
Camarata T, Krcmery J, Snyder D, Park S, Topczewski J, Simon HG
Citation:
Dev Biol. 2010 Jan 15;337(2):233-45. Epub 2009 Nov 3
Epub:
Not Epub
Abstract:
Tbx5 is involved in congenital heart disease, however, the mechanisms leading to organ malformation are greatly unknown. We...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Camarata T, Krcmery J, Snyder D, Park S, Topczewski J, Simon HG. Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation. Dev Biol. 2010 Jan 15;337(2):233-45. Epub 2009 Nov 3.

Pdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development

Authors:
Camarata T, Snyder D, Schwend T, Klosowiak J, Holtrup B, Simon H-G
Citation:
BMC Developmental Biology 2010, 10:104doi:10.1186/1471-213X-10-104
Epub:
Not Epub
Abstract:
Background Vertebrate limb development involves a reciprocal feedback loop between limb mesenchyme and the overlying apical...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Camarata T, Snyder D, Schwend T, Klosowiak J, Holtrup B, Simon H-G. Pdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development. BMC Developmental Biology 2010, 10:104doi:10.1186/1471-213X-10-104.

Peter Pan functions independently of its role in ribosome biogenesis during early eye and craniofacial cartilage development in Xenopus laevis

Authors:
Bugner V, Tecza A, Gessert S, Kühl M
Citation:
Development. 2011;[Epub ahead of print]
Epub:
Not Epub
Abstract:
The Xenopus oocyte possesses a large maternal store of ribosomes, thereby uncoupling early development from the de novo...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bugner V, Tecza A, Gessert S, Kühl M. Peter Pan functions independently of its role in ribosome biogenesis during early eye and craniofacial cartilage development in Xenopus laevis. Development. 2011;[Epub ahead of print].

Protein tyrosine and serine-threonine phosphatases in the sea urchin, Strongylocentrotus purpuratus: Identification and potential functions

Authors:
Byrum CA, Walton KD, Robertson AJ, Carbonneau S, Thomason RT, Coffman JA, McClay DR
Citation:
Dev Biol. 2006 Dec 1;300(1):194-218. Epub 2006 Aug 25.
Epub:
Not Epub
Abstract:
Protein phosphatases, in coordination with protein kinases, play crucial roles in regulation of signaling pathways. To identify...
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Byrum CA, Walton KD, Robertson AJ, Carbonneau S, Thomason RT, Coffman JA, McClay DR. Protein tyrosine and serine-threonine phosphatases in the sea urchin, Strongylocentrotus purpuratus: Identification and potential functions. Dev Biol. 2006 Dec 1;300(1):194-218. Epub 2006 Aug 25. .

Pseudoexon exclusion by antisense therapy in 6-pyruvoyl-tetrahydropterin synthase deficiency

Authors:
Brasil S, Viecelli HM, Meili D, Rassi A, Desviat LR, Pérez B, Ugarte M, Thöny B
Citation:
Hum Mutat. 2011 May 3. doi: 10.1002/humu.21529. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense oligonucleotide therapy to modulate splicing mutations in inherited diseases is emerging as a treatment option also...
Organism or Cell Type:
cell culture: human primary dermal fibroblasts
Citation Extract:
Brasil S, Viecelli HM, Meili D, Rassi A, Desviat LR, Pérez B, Ugarte M, Thöny B. Pseudoexon exclusion by antisense therapy in 6-pyruvoyl-tetrahydropterin synthase deficiency. Hum Mutat. 2011 May 3. doi: 10.1002/humu.21529. [Epub ahead of print].

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