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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements.

Authors:
Bruno IG, Jin W, Cote GJ
Citation:
Hum Mol Genet. 2004 Oct 15;13(20):2409-20.
Epub:
Not Epub
Abstract:
Alternative RNA splicing is now known to be pervasive throughout the genome and a target of human disease. We evaluated if...
Delivery Method:
scrape loading and free uptake
Organism or Cell Type:
cell culture: human SNB-19 and U251 glioblastoma cell lines, HeLa, PC3, TPC1 and Panc 28
Citation Extract:
Bruno IG, Jin W, Cote GJ. Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements.. Hum Mol Genet. 2004 Oct 15;13(20):2409-20..

Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking

Authors:
Boyadjiev SA, Fromme JC, Ben J, Chong SS, Nauta C, Hur DJ, Zhang G, Hamamoto S, Schekman R, Ravazzola M, Orci L, Eyaid W
Citation:
Nat Genet. 2006 Oct;38(10):1192-7. Epub 2006 Sep 17.
Epub:
Not Epub
Abstract:
Cranio-lenticulo-sutural dysplasia (CLSD) is an autosomal recessive syndrome characterized by late-closing fontanels, sutural...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boyadjiev SA, Fromme JC, Ben J, Chong SS, Nauta C, Hur DJ, Zhang G, Hamamoto S, Schekman R, Ravazzola M, Orci L, Eyaid W. Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking. Nat Genet. 2006 Oct;38(10):1192-7. Epub 2006 Sep 17..

Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/betacatenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek

Authors:
Caneparo L, Huang YL, Staudt N, Tada M, Ahrendt R, Kazanskaya O, Niehrs C, Houart C
Citation:
Genes Dev. 2007 Feb 15;21(4):465-480
Epub:
Not Epub
Abstract:
Dickkopf-1 (Dkk1) is a secreted protein that negatively modulates the Wnt/betacatenin pathway. Lack of Dkk1 function affects...
Citation Extract:
Caneparo L, Huang YL, Staudt N, Tada M, Ahrendt R, Kazanskaya O, Niehrs C, Houart C. Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/betacatenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes Dev. 2007 Feb 15;21(4):465-480.

Divergent segmentation mechanism in the short germ insect Tribolium revealed by giant expression and function

Authors:
Bucher G, Klingler M
Citation:
Development. 2004 Apr;131(8):1729-40. Epub 2004 Mar 17
Epub:
Not Epub
Abstract:
Segmentation is well understood in Drosophila, where all segments are determined at the blastoderm stage. In the flour beetle...
Delivery Method:
Microinjection
Organism or Cell Type:
Tribolium castaneum (flour beetle)
Citation Extract:
Bucher G, Klingler M. Divergent segmentation mechanism in the short germ insect Tribolium revealed by giant expression and function. Development. 2004 Apr;131(8):1729-40. Epub 2004 Mar 17.

Dual phosphorylation controls Cdc25 phosphatases and mitotic entry

Authors:
Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, Phillips C, Zhao H, Moody SA, Appella E, Piwnica-Worms H, Fornace AJ Jr.
Citation:
Nat Cell Biol. 2003 Jun;5(6):545-51
Epub:
Not Epub
Abstract:
Negative regulation of the Cdc25C protein phosphatase by phosphorylation on Ser 216, the 14-3-3-binding site, is an important...
Delivery Method:
Special Delivery
Organism or Cell Type:
Cell culture: HeLa Tet-ON
Citation Extract:
Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, Phillips C, Zhao H, Moody SA, Appella E, Piwnica-Worms H, Fornace AJ Jr.. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol. 2003 Jun;5(6):545-51.

ELOVL4 Expression and Morpholino Knock-Down in Zebrafish

Authors:
Cameron DJ, Katz T, Chen Y, Trede N, Zhang K
Citation:
Invest. Ophthalmol. Vis. Sci. May 2006; 47: 4593
Epub:
Not Epub
Abstract:
Purpose: ELOVL4 has been linked to early onset autosomal dominant macular degeneration. The Zebrafish genome contains a gene...
Organism or Cell Type:
zebrafish
Citation Extract:
Cameron DJ, Katz T, Chen Y, Trede N, Zhang K. ELOVL4 Expression and Morpholino Knock-Down in Zebrafish. Invest. Ophthalmol. Vis. Sci. May 2006; 47: 4593.

Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation

Authors:
Budi EH, Patterson LB, Parichy DM
Citation:
Development. 2008 Aug;135(15):2603-2614. Epub 2008 May 28.
Epub:
Not Epub
Abstract:
Vertebrate pigment cells are derived from neural crest cells and are a useful system for studying neural crest-derived traits...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Budi EH, Patterson LB, Parichy DM. Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation. Development. 2008 Aug;135(15):2603-2614. Epub 2008 May 28..

Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins

Authors:
Callery EM, Park CY, Xu X, Zhu H, Smith JC, Thomsen GH
Citation:
Open Biol. 2012 April; 2(4): 120060. doi: 10.1098/rsob.120060
Epub:
Not Epub
Abstract:
Transforming growth factor β superfamily members signal through Smad transcription factors. Bone morphogenetic proteins (BMPs)...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Callery EM, Park CY, Xu X, Zhu H, Smith JC, Thomsen GH. Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins. Open Biol. 2012 April; 2(4): 120060. doi: 10.1098/rsob.120060.

Essential role of spi-1-like (spi-1l) in zebrafish myeloid cell differentiation

Authors:
Bukrinsky A, Griffin KJ, Zhao Y, Lin S, Banerjee U
Citation:
Blood. 2009 Feb 26;113(9):2038-46. Epub 2009 Jan 8
Epub:
Not Epub
Abstract:
The ETS protein Spi-1/Pu.1 plays a pivotal and widespread role throughout hematopoiesis in many species. This study describes...
Organism or Cell Type:
zebrafish
Citation Extract:
Bukrinsky A, Griffin KJ, Zhao Y, Lin S, Banerjee U. Essential role of spi-1-like (spi-1l) in zebrafish myeloid cell differentiation. Blood. 2009 Feb 26;113(9):2038-46. Epub 2009 Jan 8.

Evolutionarily conserved function of Gbx2 in anterior hindbrain development

Authors:
Burroughs-Garcia J, Sittaramane V, Chandrasekhar A, Waters ST
Citation:
Dev. Dyn. 2011 [Epub ahead of print]
Epub:
Not Epub
Abstract:
The amino acid sequence across the DNA-binding homeodomain of Gbx2 is highly conserved across multiple species. In mice, Gbx2...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burroughs-Garcia J, Sittaramane V, Chandrasekhar A, Waters ST. Evolutionarily conserved function of Gbx2 in anterior hindbrain development. Dev. Dyn. 2011 [Epub ahead of print].

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