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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12062 scientific papers returned from the database with the search filters currently being used below.

Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis

Authors:
Branam AM, Hoffman GG, Pelegri F, Greenspan DS
Citation:
Dev Biol. 2010 May 15;341(2):444-58. Epub 2010 Mar 11
Epub:
Not Epub
Abstract:
Chordin is the prototype of a group of cysteine-rich domain-containing proteins that bind and modulate signaling of various...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Branam AM, Hoffman GG, Pelegri F, Greenspan DS. Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis. Dev Biol. 2010 May 15;341(2):444-58. Epub 2010 Mar 11.

Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss

Authors:
Campbell WA, Yang H, Zetterberg H, Baulac S, Sears JA, Liu T, Wong ST, Zhong TP, Xia W
Citation:
J Neurochem. 2006 Mar;96(5):1423-40. Epub 2006 Feb 8
Epub:
Not Epub
Abstract:
gamma-Secretase cleavage, mediated by a complex of presenilin, presenilin enhancer (Pen-2), nicastrin, and Aph-1, is the final...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Campbell WA, Yang H, Zetterberg H, Baulac S, Sears JA, Liu T, Wong ST, Zhong TP, Xia W. Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss. J Neurochem. 2006 Mar;96(5):1423-40. Epub 2006 Feb 8.

Zebrafish Numb and Numblike Are Involved in Primitive Erythrocyte Differentiation

Authors:
Bresciani E, Confalonieri S, Cermenati S, Cimbro S, Foglia E, Beltrame M, Di Fiore PP, Cotelli F
Citation:
PLoS ONE. 2010;5(12): e14296. doi:10.1371/journal.pone.0014296
Epub:
Not Epub
Abstract:
Background Notch signaling is an evolutionarily conserved regulatory circuitry implicated in cell fate determination in various...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bresciani E, Confalonieri S, Cermenati S, Cimbro S, Foglia E, Beltrame M, Di Fiore PP, Cotelli F. Zebrafish Numb and Numblike Are Involved in Primitive Erythrocyte Differentiation. PLoS ONE. 2010;5(12): e14296. doi:10.1371/journal.pone.0014296.

A gene network that coordinates preplacodal competence and neural crest specification in zebrafish

Authors:
Bhat N, Kwon HJ, Riley BB
Citation:
Dev Biol. 2012 Oct 16. doi:pii: S0012-1606(12)00553-2. 10.1016/j.ydbio.2012.10.012. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Preplacodal ectoderm (PPE) and neural crest (NC) are specified at the interface of neural and nonneural ectoderm and together...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhat N, Kwon HJ, Riley BB. A gene network that coordinates preplacodal competence and neural crest specification in zebrafish. Dev Biol. 2012 Oct 16. doi:pii: S0012-1606(12)00553-2. 10.1016/j.ydbio.2012.10.012. [Epub ahead of print].

A Mutation in a Ganglioside Biosynthetic Enzyme, ST3GAL5, Results in Salt & Pepper Syndrome, a Neurocutaneous Disorder with Altered Glycolipid and Glycoprotein Glycosylation

Authors:
Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE
Citation:
Hum Mol Genet. 2013 Sep 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
\"Salt & Pepper\" syndrome is an autosomal recessive condition characterized by severe intellectual disability,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE. A Mutation in a Ganglioside Biosynthetic Enzyme, ST3GAL5, Results in Salt & Pepper Syndrome, a Neurocutaneous Disorder with Altered Glycolipid and Glycoprotein Glycosylation. Hum Mol Genet. 2013 Sep 10. [Epub ahead of print].

A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification

Authors:
Bonano M, Tríbulo C, De Calisto J, Marchant L, Sánchez SS, Mayor R, Aybar MJ
Citation:
Dev Biol. 2008 Aug 15. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The neural crest is induced at the border of the neural plate in a multistep process by signals emanated from the epidermis,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bonano M, Tríbulo C, De Calisto J, Marchant L, Sánchez SS, Mayor R, Aybar MJ. A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification. Dev Biol. 2008 Aug 15. [Epub ahead of print] .

A primer for morpholino use in zebrafish

Authors:
Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC
Citation:
Zebrafish. 2009 Mar;6(1):69-77
Epub:
Not Epub
Abstract:
Abstract Morpholino oligonucleotides are the most common anti-sense \"knockdown\" technique used in zebrafish (Danio...
Organism or Cell Type:
zebrafish
Citation Extract:
Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC. A primer for morpholino use in zebrafish. Zebrafish. 2009 Mar;6(1):69-77.

A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs

Authors:
Betancur P, Sauka-Spengler T, Bronner M
Citation:
Development. 2011 Sep;138(17):3689-98. Epub 2011 Jul 20
Epub:
Not Epub
Abstract:
The otic placode, a specialized region of ectoderm, gives rise to components of the inner ear and shares many characteristics...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Betancur P, Sauka-Spengler T, Bronner M. A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs. Development. 2011 Sep;138(17):3689-98. Epub 2011 Jul 20.

A zebrafish model of Axenfeld-Rieger Syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development

Authors:
Bohnsack BL, Kasprick DS, Kish PE, Goldman D, Kahana A
Citation:
Invest Ophthalmol Vis Sci. 2011 Nov 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Purpose.The homeobox transcription factor PITX2 is a known regulator of mammalian ocular development, and human PITX2 mutations...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bohnsack BL, Kasprick DS, Kish PE, Goldman D, Kahana A. A zebrafish model of Axenfeld-Rieger Syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development. Invest Ophthalmol Vis Sci. 2011 Nov 28. [Epub ahead of print].

Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation

Authors:
Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT, Sekkali B, Bronchain O, Vleminckx K, Locker M, Perron M
Citation:
Development. 2012 Oct;139(19):3499-509. doi: 10.1242/dev.079582. Epub 2012 Aug 16
Epub:
Not Epub
Abstract:
Continuous neurogenesis in the adult nervous system requires a delicate balance between proliferation and differentiation....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT, Sekkali B, Bronchain O, Vleminckx K, Locker M, Perron M. Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation. Development. 2012 Oct;139(19):3499-509. doi: 10.1242/dev.079582. Epub 2012 Aug 16.

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