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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)

Authors:
Chiang AP, Beck JS, Yen HJ, Tayeh MK, Scheetz TE, Swiderski RE, Nishimura DY, Braun TA, Kim KY, Huang J, Elbedour K, Carmi R, Slusarski DC, Casavant TL, Stone EM, Sheffield VC
Citation:
Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6287-92. Epub 2006 Apr 10
Epub:
Not Epub
Abstract:
The identification of mutations in genes that cause human diseases has largely been accomplished through the use of positional...
Organism or Cell Type:
zebrafish
Citation Extract:
Chiang AP, Beck JS, Yen HJ, Tayeh MK, Scheetz TE, Swiderski RE, Nishimura DY, Braun TA, Kim KY, Huang J, Elbedour K, Carmi R, Slusarski DC, Casavant TL, Stone EM, Sheffield VC. Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6287-92. Epub 2006 Apr 10.

Hop is an unusual homeobox gene that modulates cardiac development.

Authors:
Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, Mullins MC, Epstein JA.
Citation:
Cell 2002 Sep 20;110(6):713-23
Epub:
Not Epub
Abstract:
Hop is a small, divergent homeodomain protein that lacks certain conserved residues required for DNA binding. Hop gene...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, Mullins MC, Epstein JA.. Hop is an unusual homeobox gene that modulates cardiac development.. Cell 2002 Sep 20;110(6):713-23.

Identification and characterization of alternative promoters of zebrafish Rtn-4/Nogo genes in cultured cells and zebrafish embryos

Authors:
Chen YC, Wu BK, Chu CY, Cheng CH, Han HW, Chen GD, Lee MT, Hwang PP, Kawakami K, Chang CC, Huang CJ
Citation:
Nucleic Acids Res. 2010 Apr 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In mammals, the Nogo family consists of Nogo-A, Nogo-B and Nogo-C. However, there are three Rtn-4/Nogo-related transcripts were...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YC, Wu BK, Chu CY, Cheng CH, Han HW, Chen GD, Lee MT, Hwang PP, Kawakami K, Chang CC, Huang CJ. Identification and characterization of alternative promoters of zebrafish Rtn-4/Nogo genes in cultured cells and zebrafish embryos. Nucleic Acids Res. 2010 Apr 8. [Epub ahead of print].

Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos

Authors:
Cheong SM, Kim H, Han JK
Citation:
J Biol Chem. 2009 Apr 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Phosphotyrosine binding (PTB) domains, which are found in a large number of proteins, have been implicated in signal...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cheong SM, Kim H, Han JK. Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos. J Biol Chem. 2009 Apr 22. [Epub ahead of print].

Impaired Cardiovascular Function Caused by Different Stressors Elicits a Common Pathological and Transcriptional Response in Zebrafish Embryos

Authors:
Chen J
Citation:
Zebrafish. 2013;[Epub ahead of print] doi:10.1089/zeb.2013.0875
Epub:
Not Epub
Abstract:
Zebrafish embryos have been widely used to study the genes and processes needed for normal vertebrate heart development. We...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J. Impaired Cardiovascular Function Caused by Different Stressors Elicits a Common Pathological and Transcriptional Response in Zebrafish Embryos. Zebrafish. 2013;[Epub ahead of print] doi:10.1089/zeb.2013.0875.

Inactivation of Myosin binding protein C homolog in zebrafish as a model for human cardiac hypertrophy and diastolic dysfunction

Authors:
Chen YH, Pai CW, Huang SW, Chang SN, Lin LY, Chiang FT, Lin JL, Hwang JJ, Tsai CT
Citation:
J Am Heart Assoc. 2013 Sep 18;2(5):e000231. doi: 10.1161/JAHA.113.000231
Epub:
Not Epub
Abstract:
BACKGROUND: Sudden cardiac death due to malignant ventricular arrhythmia is a devastating manifestation of cardiac hypertrophy...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YH, Pai CW, Huang SW, Chang SN, Lin LY, Chiang FT, Lin JL, Hwang JJ, Tsai CT. Inactivation of Myosin binding protein C homolog in zebrafish as a model for human cardiac hypertrophy and diastolic dysfunction. J Am Heart Assoc. 2013 Sep 18;2(5):e000231. doi: 10.1161/JAHA.113.000231.

Insulin receptor signaling in the development of neuronal structure and function

Authors:
Chiu SL, Cline HT
Citation:
Neural Dev. 2010 Mar 15;5:7
Epub:
Not Epub
Abstract:
Sensory experience plays a crucial role in regulating neuronal shape and in developing synaptic contacts during brain formation...
Organism or Cell Type:
Xenopus (review)
Citation Extract:
Chiu SL, Cline HT. Insulin receptor signaling in the development of neuronal structure and function. Neural Dev. 2010 Mar 15;5:7.

Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo

Authors:
Chiu SL, Chen CM, Cline HT
Citation:
Neuron. 2008 Jun 12;58(5):708-19
Epub:
Not Epub
Abstract:
Insulin receptor signaling has been postulated to play a role in synaptic plasticity; however, the function of the insulin...
Organism or Cell Type:
Xenopus
Citation Extract:
Chiu SL, Chen CM, Cline HT. Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo. Neuron. 2008 Jun 12;58(5):708-19.

Kazrin, and its binding partners ARVCF- and delta-catenin, are required for Xenopus laevis craniofacial development

Authors:
Cho K, Lee M, Gu D, Munoz WA, Ji H, Kloc M, McCrea PD
Citation:
Dev Dyn. 2011 Oct 25. doi: 10.1002/dvdy.22721. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The novel adaptor protein Kazrin associates with multifunctional entities including p120-subfamily members (ARVCF-, delta-, and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Cho K, Lee M, Gu D, Munoz WA, Ji H, Kloc M, McCrea PD. Kazrin, and its binding partners ARVCF- and delta-catenin, are required for Xenopus laevis craniofacial development. Dev Dyn. 2011 Oct 25. doi: 10.1002/dvdy.22721. [Epub ahead of print].

Knockdown of zebrafish Na(v)1.6 sodium channel impairs embryonic locomotor activities

Authors:
Chen YH, Huang FL, Cheng YC, Wu CJ, Yang CN, Tsay HJ
Citation:
J Biomed Sci. 2008 Jan;15(1):69-78. Epub 2007 Aug 9.
Epub:
Not Epub
Abstract:
Although multiple subtypes of sodium channels are expressed in most neurons, the specific contributions of the individual...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YH, Huang FL, Cheng YC, Wu CJ, Yang CN, Tsay HJ. Knockdown of zebrafish Na(v)1.6 sodium channel impairs embryonic locomotor activities. J Biomed Sci. 2008 Jan;15(1):69-78. Epub 2007 Aug 9..

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