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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Depletion of the cell-cycle inhibitor p27(Xic1) impairs neuronal differentiation and increases the number of ElrC(+) progenitor cells in Xenopus tropicalis

Authors:
Carruthers S, Mason J, Papalopulu N
Citation:
Mech Dev. 2003 May;120(5):607-16
Epub:
Not Epub
Abstract:
The Xenopus p27(Xic1) gene encodes a cyclin dependent kinase (CDK) inhibitor of the Cip/Kip family. We have previously shown...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Carruthers S, Mason J, Papalopulu N. Depletion of the cell-cycle inhibitor p27(Xic1) impairs neuronal differentiation and increases the number of ElrC(+) progenitor cells in Xenopus tropicalis. Mech Dev. 2003 May;120(5):607-16.

Dissection of angiogenic signaling in zebrafish using a chemical genetic approach

Authors:
Chan J, Bayliss PE, Wood JM, Roberts TM
Citation:
Cancer Cell. 2002. 1(3):257-267
Epub:
Not Epub
Abstract:
Striking homology between signaling molecules in zebrafish and humans suggests that compounds known to inhibit human kinases...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chan J, Bayliss PE, Wood JM, Roberts TM. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach. Cancer Cell. 2002. 1(3):257-267.

Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway

Authors:
Cavodeassi F, Carreira-Barbosa F, Young RM, Concha ML, Allende ML, Houart C, Tada M, Wilson SW
Citation:
Neuron. 2005 Jul 7;47(1):43-56
Epub:
Not Epub
Abstract:
During regional patterning of the anterior neural plate, a medially positioned domain of cells is specified to adopt retinal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cavodeassi F, Carreira-Barbosa F, Young RM, Concha ML, Allende ML, Houart C, Tada M, Wilson SW. Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway. Neuron. 2005 Jul 7;47(1):43-56.

Electroporation of DNA, RNA, and morpholinos into zebrafish embryos

Authors:
Cerda GA, Thomas JE, Allende ML, Karlstrom RO, Palma V
Citation:
Methods. 2006 Jul;39(3):207-11.
Epub:
Not Epub
Abstract:
The combination of accessible embryology and forward genetic techniques has made zebrafish a powerful model system for the...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Cerda GA, Thomas JE, Allende ML, Karlstrom RO, Palma V. Electroporation of DNA, RNA, and morpholinos into zebrafish embryos. Methods. 2006 Jul;39(3):207-11..

Eph/Ephrin signalling maintains eye field segregation from adjacent neural plate territories during forebrain morphogenesis

Authors:
Cavodeassi F, Ivanovitch K, Wilson SW
Citation:
Development. 2013 Oct;140(20):4193-4202. Epub 2013 Sep 11
Epub:
Not Epub
Abstract:
During forebrain morphogenesis, there is extensive reorganisation of the cells destined to form the eyes, telencephalon and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cavodeassi F, Ivanovitch K, Wilson SW. Eph/Ephrin signalling maintains eye field segregation from adjacent neural plate territories during forebrain morphogenesis. Development. 2013 Oct;140(20):4193-4202. Epub 2013 Sep 11.

ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles

Authors:
Chambon JP, Nakayama A, Takamura K, McDougall A, Satoh N
Citation:
Development. 2007 Mar;134(6):1203-19
Epub:
Not Epub
Abstract:
In ascidian tadpoles, metamorphosis is triggered by a polarized wave of apoptosis, via mechanisms that are largely unknown. We...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Chambon JP, Nakayama A, Takamura K, McDougall A, Satoh N. ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles. Development. 2007 Mar;134(6):1203-19.

Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent

Authors:
Cha HJ, Byrom M, Mead PE, Ellington AD, Wallingford JB, Marcotte EM
Citation:
PLoS Biol. 2012 Aug;10(8):e1001379. Epub 2012 Aug 21
Epub:
Not Epub
Abstract:
Studies in diverse organisms have revealed a surprising depth to the evolutionary conservation of genetic modules. For example...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cha HJ, Byrom M, Mead PE, Ellington AD, Wallingford JB, Marcotte EM. Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol. 2012 Aug;10(8):e1001379. Epub 2012 Aug 21.

Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

Authors:
Chaki M, Airik R, Ghosh AK, Giles RH, Chen R, Slaats GG, Wang H, Hurd TW, Zhou W, Cluckey A, Gee HY, Ramaswami G, Hong CJ, Hamilton BA, Cervenka I, Ganji RS, Bryja V, Arts HH, van Reeuwijk J, Oud MM, Letteboer SJ, Roepman R, Husson H, Ibraghimov-Beskrovnaya O, Yasunaga T, Walz G, Eley L, Sayer JA, Schermer B, Liebau MC, Benzing T, Le Corre S, Drummond I, Janssen S, Allen SJ, Natarajan S, O'Toole JF, Attanasio M, Saunier S, Antignac C, Koenekoop RK, Ren H, Lopez I, Nayir A, Stoetzel C, Dollfus H, Massoudi R, Gleeson JG, Andreoli SP, Doherty DG, Lindstrad A, Golzio C, Katsanis N, Pape L, Abboud EB, Al-Rajhi AA, Lewis RA, Omran H, Lee EY, Wang S, Sekiguchi JM, Saunders R, Johnson CA, Garner E, Vanselow K, Andersen JS, Shlomai J, Nurnberg G, Nurnberg P, Levy S, Smogorzewska A, Otto EA, Hildebrandt F
Citation:
Cell. 2012 Aug 3;150(3):533-48
Epub:
Not Epub
Abstract:
Nephronophthisis-related ciliopathies (NPHP-RC) are degenerative recessive diseases that affect kidney, retina, and brain....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chaki M, Airik R, Ghosh AK, Giles RH, Chen R, Slaats GG, Wang H, Hurd TW, Zhou W, Cluckey A, Gee HY, Ramaswami G, Hong CJ, Hamilton BA, Cervenka I, Ganji RS, Bryja V, Arts HH, van Reeuwijk J, Oud MM, Letteboer SJ, Roepman R, Husson H, Ibraghimov-Beskrovnaya O, Yasunaga T, Walz G, Eley L, Sayer JA, Schermer B, Liebau MC, Benzing T, Le Corre S, Drummond I, Janssen S, Allen SJ, Natarajan S, O'Toole JF, Attanasio M, Saunier S, Antignac C, Koenekoop RK, Ren H, Lopez I, Nayir A, Stoetzel C, Dollfus H, Massoudi R, Gleeson JG, Andreoli SP, Doherty DG, Lindstrad A, Golzio C, Katsanis N, Pape L, Abboud EB, Al-Rajhi AA, Lewis RA, Omran H, Lee EY, Wang S, Sekiguchi JM, Saunders R, Johnson CA, Garner E, Vanselow K, Andersen JS, Shlomai J, Nurnberg G, Nurnberg P, Levy S, Smogorzewska A, Otto EA, Hildebrandt F. Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling. Cell. 2012 Aug 3;150(3):533-48.

Expression and function of KCNQ channels in larval zebrafish

Authors:
Chege SW, Hortopan GA, Dinday M, Baraban SC
Citation:
Dev Neurobiol. 2012 Feb;72(2):186-98. doi: 10.1002/dneu.20937.
Epub:
Not Epub
Abstract:
Members of the Kv7 family generate a sub-threshold potassium current, termed M-current, that regulates the excitability of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chege SW, Hortopan GA, Dinday M, Baraban SC. Expression and function of KCNQ channels in larval zebrafish. Dev Neurobiol. 2012 Feb;72(2):186-98. doi: 10.1002/dneu.20937..

Ff1b is required for the development of steroidogenic component of the zebrafish interrenal organ

Authors:
Chai C, Liu YW, Chan WK
Citation:
Dev Biol. 2003 Aug 1;260(1):226-44
Epub:
Not Epub
Abstract:
The zebrafish ftz-f1 gene, ff1b, is activated in two cell clusters lateral to the midline in the trunk during late...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chai C, Liu YW, Chan WK. Ff1b is required for the development of steroidogenic component of the zebrafish interrenal organ. Dev Biol. 2003 Aug 1;260(1):226-44.

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