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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

MMP-2 plays an essential role in producing epithelial-mesenchymal transformations in the avian embryo

Authors:
Duong TD, Erickson CA
Citation:
Dev Dyn. 2004 Jan;229(1):42-53
Epub:
Not Epub
Abstract:
To investigate the roles that matrix-degrading proteases may have in development of the chicken embryo, we documented the...
Delivery Method:
Microinjection
Organism or Cell Type:
chick embryo
Citation Extract:
Duong TD, Erickson CA. MMP-2 plays an essential role in producing epithelial-mesenchymal transformations in the avian embryo. Dev Dyn. 2004 Jan;229(1):42-53.

montalcino, A zebrafish model for variegate porphyria

Authors:
Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI, Tübingen 2000 Screen Consortium
Citation:
Exp Hematol. 2008 Sep;36(9):1132-1142. Epub 2008 Jun 11.
Epub:
Not Epub
Abstract:
OBJECTIVE: Inherited or acquired mutations in the heme biosynthetic pathway leads to a debilitating class of diseases...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI, Tübingen 2000 Screen Consortium. montalcino, A zebrafish model for variegate porphyria. Exp Hematol. 2008 Sep;36(9):1132-1142. Epub 2008 Jun 11..

Mos is not required for the initiation of meiotic maturation in Xenopus oocytes

Authors:
Dupre A, Jessus C, Ozon R, Haccard O
Citation:
EMBO J. 2002 Aug 1;21(15):4026-36
Epub:
Not Epub
Abstract:
In Xenopus oocytes, the c-mos proto-oncogene product has been proposed to act downstream of progesterone to control the entry...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Dupre A, Jessus C, Ozon R, Haccard O. Mos is not required for the initiation of meiotic maturation in Xenopus oocytes. EMBO J. 2002 Aug 1;21(15):4026-36.

Mutations in the human SIX3 gene in holoprosencephaly are loss of function

Authors:
Domené S, Roessler E, El-Jaick KB, Snir M, Brown JL, Vélez JI, Bale S, Lacbawan F, Muenke M, Feldman B
Citation:
Hum Mol Genet. 2008 Dec 15;17(24):3919-28. Epub 2008 Sep 12
Epub:
Not Epub
Abstract:
Holoprosencephaly (HPE) is the most common developmental anomaly of the human forebrain; however, the genetics of this...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Domené S, Roessler E, El-Jaick KB, Snir M, Brown JL, Vélez JI, Bale S, Lacbawan F, Muenke M, Feldman B. Mutations in the human SIX3 gene in holoprosencephaly are loss of function. Hum Mol Genet. 2008 Dec 15;17(24):3919-28. Epub 2008 Sep 12.

Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm

Authors:
Doyle AJ, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D, Gillis E, Mortier G, Homfray T, Sauls K, Norris RA, Huso ND, Leahy D, Mohr DW, Caulfield MJ, Scott AF, Destrée A, Hennekam RC, Arn PH, Curry CJ, Van Laer L, McCallion AS, Loeys BL, Dietz HC
Citation:
Nat Genet. 2012 Sep 30. doi: 10.1038/ng.2421. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Elevated transforming growth factor (TGF)-β signaling has been implicated in the pathogenesis of syndromic presentations of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Doyle AJ, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D, Gillis E, Mortier G, Homfray T, Sauls K, Norris RA, Huso ND, Leahy D, Mohr DW, Caulfield MJ, Scott AF, Destrée A, Hennekam RC, Arn PH, Curry CJ, Van Laer L, McCallion AS, Loeys BL, Dietz HC. Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm. Nat Genet. 2012 Sep 30. doi: 10.1038/ng.2421. [Epub ahead of print].

Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish

Authors:
EauClaire SF, Cui S, Ma L, Matous J, Marlow FL, Gupta T, Burgess HA, Abrams EW, Kapp LD, Granato M, Mullins MC, Matthews RP
Citation:
Dev Biol. 2012 Mar 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We identified three zebrafish mutants with defects in biliary development. One of these mutants, pekin (pn), also demonstrated...
Organism or Cell Type:
zebrafish
Citation Extract:
EauClaire SF, Cui S, Ma L, Matous J, Marlow FL, Gupta T, Burgess HA, Abrams EW, Kapp LD, Granato M, Mullins MC, Matthews RP. Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish. Dev Biol. 2012 Mar 16. [Epub ahead of print].

Neural and eye-specific defects associated with loss of the Imitation Switch (ISWI) chromatin remodeler in Xenopus laevis

Authors:
Dirscherl SS, Henry JJ, Krebs JE
Citation:
Mech Dev. 2005 Nov;122(11):1157-70. Epub 2005 Aug 29.
Epub:
Not Epub
Abstract:
Imitation Switch (ISWI) is a member of the SWI2/SNF2 superfamily of ATP-dependent chromatin remodelers, which regulate...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Dirscherl SS, Henry JJ, Krebs JE. Neural and eye-specific defects associated with loss of the Imitation Switch (ISWI) chromatin remodeler in Xenopus laevis. Mech Dev. 2005 Nov;122(11):1157-70. Epub 2005 Aug 29..

Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection

Authors:
Dichmann DS, Harland RM
Citation:
Dev Biol. 2010 Oct 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neuronal subtypes originate from an undifferentiated neural epithelium that is progressively divided into progenitor domains by...
Delivery Method:
Microinjection
Organism or Cell Type:
X.laevis & X.tropicalis
Citation Extract:
Dichmann DS, Harland RM. Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection. Dev Biol. 2010 Oct 27. [Epub ahead of print].

Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo

Authors:
Duboc V, Lapraz F, Saudemont A, Bessodes N, Mekpoh F, Haillot E, Quirin M, Lepage T
Citation:
Development. 2010 Jan;137(2):223-35
Epub:
Not Epub
Abstract:
Nodal factors play fundamental roles in induction and patterning of the mesoderm and endoderm in vertebrates, but whether this...
Delivery Method:
Microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Duboc V, Lapraz F, Saudemont A, Bessodes N, Mekpoh F, Haillot E, Quirin M, Lepage T. Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo. Development. 2010 Jan;137(2):223-35.

Nodal and BMP2/4 Signaling Organizes the Oral-Aboral Axis of the Sea Urchin Embryo

Authors:
Duboc V, Rottinger E, Besnardeau L, Lepage T
Citation:
Dev Cell. 2004 Mar;6(3):397-410
Epub:
Not Epub
Abstract:
In the sea urchin embryo, the oral-aboral axis is specified after fertilization by mechanisms that are largely unknown. We...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Duboc V, Rottinger E, Besnardeau L, Lepage T. Nodal and BMP2/4 Signaling Organizes the Oral-Aboral Axis of the Sea Urchin Embryo. Dev Cell. 2004 Mar;6(3):397-410.

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