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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Dual roles for rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue

Authors:
Deng Q, Yoo SK, Cavnar PJ, Green JM, Huttenlocher A
Citation:
Dev Cell. 2011 Oct 18;21(4):735-45
Epub:
Not Epub
Abstract:
Neutrophil homeostasis is essential for host defense. Here we identify dual roles for Rac2 during neutrophil homeostasis using...
Organism or Cell Type:
zebrafish
Citation Extract:
Deng Q, Yoo SK, Cavnar PJ, Green JM, Huttenlocher A. Dual roles for rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue. Dev Cell. 2011 Oct 18;21(4):735-45.

Eukaryotic initiation factor 6 (eif6) overexpression affects eye development in Xenopus laevis

Authors:
De Marco N, Tussellino M, Vitale A, Campanella C
Citation:
Differentiation. 2011 May 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The translation initiation factor eif6 has been implicated as a regulator of ribosome assembly, selective mRNA translation and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
De Marco N, Tussellino M, Vitale A, Campanella C. Eukaryotic initiation factor 6 (eif6) overexpression affects eye development in Xenopus laevis. Differentiation. 2011 May 19. [Epub ahead of print].

Evidence for the requirement of 14-3-3eta (YWHAH) in meiotic spindle assembly during mouse oocyte maturation

Authors:
De S, Kline D
Citation:
BMC Dev Biol. 2013;13:10 doi:10.1186/1471-213X-13-10
Epub:
Not Epub
Abstract:
Background The 14-3-3 (YWHA) proteins are central mediators in various cellular signaling pathways regulating development and...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
De S, Kline D. Evidence for the requirement of 14-3-3eta (YWHAH) in meiotic spindle assembly during mouse oocyte maturation. BMC Dev Biol. 2013;13:10 doi:10.1186/1471-213X-13-10.

Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing

Authors:
Del Viso F, Bhattacharya D, Kong Y, Gilchrist MJ, Khokha MK
Citation:
BMC Genomics. 2012 Nov 21;13:649. doi: 10.1186/1471-2164-13-649
Epub:
Not Epub
Abstract:
BACKGROUND: Exome sequencing has transformed human genetic analysis and may do the same for other vertebrate model systems....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Del Viso F, Bhattacharya D, Kong Y, Gilchrist MJ, Khokha MK. Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing. BMC Genomics. 2012 Nov 21;13:649. doi: 10.1186/1471-2164-13-649.

Functional genomic analysis of the Wnt-wingless signaling pathway

Authors:
DasGupta R, Kaykas A, Moon RT, Perrimon N
Citation:
Science. 2005 May 6;308(5723):826-33. Epub 2005 Apr 7
Epub:
Not Epub
Abstract:
The Wnt-Wingless (Wg) pathway is one of a core set of evolutionarily conserved signaling pathways that regulates many aspects...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
DasGupta R, Kaykas A, Moon RT, Perrimon N. Functional genomic analysis of the Wnt-wingless signaling pathway. Science. 2005 May 6;308(5723):826-33. Epub 2005 Apr 7.

Functional genomics in virology and antiviral drug discovery

Authors:
DeFilippis V, Raggo C, Moses A, Fruh K.
Citation:
Trends Biotechnol. 2003 Oct;21(10):452-7. Review
Epub:
Not Epub
Abstract:
Virology research and antiviral drug discovery are poised to benefit from the post-genomic revolution for three main reasons....
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
DeFilippis V, Raggo C, Moses A, Fruh K.. Functional genomics in virology and antiviral drug discovery. Trends Biotechnol. 2003 Oct;21(10):452-7. Review.

Generation and characterization of FMR1 knockout zebrafish

Authors:
den Broeder MJ, van der Linde H, Brouwer JR, Oostra BA, Willemsen R, Ketting RF
Citation:
PLoS One. 2009 Nov 19;4(11):e7910
Epub:
Not Epub
Abstract:
Fragile X syndrome (FXS) is one of the most common known causes of inherited mental retardation. The gene mutated in FXS is...
Organism or Cell Type:
zebrafish
Citation Extract:
den Broeder MJ, van der Linde H, Brouwer JR, Oostra BA, Willemsen R, Ketting RF. Generation and characterization of FMR1 knockout zebrafish. PLoS One. 2009 Nov 19;4(11):e7910.

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

Authors:
Daugaard M, Nitsch R, Razaghi B, McDonald L, Jarrar A, Torrino S, Castillo-Lluva S, Rotblat B, Li L, Malliri A, Lemichez E, Mettouchi A, Berman JN, Penninger JM, Sorensen PH
Citation:
Nat Commun. 2013 Jul 17;4:2180. doi: 10.1038/ncomms3180
Epub:
Not Epub
Abstract:
The Hace1-HECT E3 ligase is a tumor suppressor that ubiquitylates the activated GTP-bound form of the Rho family GTPase Rac1,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Daugaard M, Nitsch R, Razaghi B, McDonald L, Jarrar A, Torrino S, Castillo-Lluva S, Rotblat B, Li L, Malliri A, Lemichez E, Mettouchi A, Berman JN, Penninger JM, Sorensen PH. Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes. Nat Commun. 2013 Jul 17;4:2180. doi: 10.1038/ncomms3180.

Histone deacetylase-4 is required during early cranial neural crest development for generation of the zebrafish palatal skeleton

Authors:
DeLaurier A, Nakamura Y, Braasch I, Khanna V, Kato H, Wakitani S, Postlethwait JH, Kimmel CB
Citation:
BMC Dev Biol. 2012;12:16 doi:10.1186/1471-213X-12-16
Epub:
Not Epub
Abstract:
Background Histone deacetylase-4 (Hdac4) is a class II histone deacetylase that inhibits the activity of transcription factors...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
DeLaurier A, Nakamura Y, Braasch I, Khanna V, Kato H, Wakitani S, Postlethwait JH, Kimmel CB. Histone deacetylase-4 is required during early cranial neural crest development for generation of the zebrafish palatal skeleton. BMC Dev Biol. 2012;12:16 doi:10.1186/1471-213X-12-16.

Identification and functional analysis of endothelial tip cell-enriched genes

Authors:
Del Toro R, Prahst C, Mathivet T, Siegfried G, Kaminker JS, Larrivee B, Breant C, Duarte A, Takakura N, Fukamizu A, Penninger J, Eichmann A
Citation:
Blood. 2010 Aug 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Sprouting of developing blood vessels is mediated by specialized motile endothelial cells localized at the tips of growing...
Organism or Cell Type:
zebrafish
Citation Extract:
Del Toro R, Prahst C, Mathivet T, Siegfried G, Kaminker JS, Larrivee B, Breant C, Duarte A, Takakura N, Fukamizu A, Penninger J, Eichmann A. Identification and functional analysis of endothelial tip cell-enriched genes. Blood. 2010 Aug 12. [Epub ahead of print].

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