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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase
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Citation:
Cell. 2005 Apr 8;121(1):87-99 Epub:
Not Epub Abstract:
TGF-beta signaling is essential for development and proliferative homeostasis. During embryogenesis, maternal determinants act... Delivery Method:
microinjection in embryos, Special Delivery in culture Organism or Cell Type:
Xenopus and HEK293T cells Citation Extract: Dupont S, Zacchigna L, Cordenonsi M, Soligo S, Adorno M, Rugge M, Piccolo S. Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. Cell. 2005 Apr 8;121(1):87-99. |
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas
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Citation:
Genes Dev. 2008 Jun 1;22(11):1445-50 Epub:
Not Epub Abstract:
The mechanisms regulating pancreatic endocrine versus exocrine fate are not well defined. By analyzing the effects of Ptf1a... Organism or Cell Type:
zebrafish Citation Extract: Dong PD, Provost E, Leach SD, Stainier DY. Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. Genes Dev. 2008 Jun 1;22(11):1445-50. |
Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1
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Citation:
Cell 2002 Nov 27;111(5):647-59 Epub:
Not Epub Abstract:
The signals directing primordial germ cell (PGC) migration in vertebrates are largely unknown. We demonstrate that sdf-1 mRNA... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Doitsidou M, Reichman-Fried M, Stebler J, Koprunner M, Dorries J, Meyer D, Esguerra CV, Leung T, Raz E.. Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1. Cell 2002 Nov 27;111(5):647-59. |
Heat-shock protein 90alpha1 is required for organized myofibril assembly in skeletal muscles of zebrafish embryos
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Citation:
Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):554-9. Epub 2008 Jan 8 Epub:
Not Epub Abstract:
Heat-shock protein 90alpha (Hsp90alpha) is a member of the molecular chaperone family involved in protein folding and assembly... Organism or Cell Type:
zebrafish Citation Extract: Du SJ, Li H, Bian Y, Zhong Y. Heat-shock protein 90alpha1 is required for organized myofibril assembly in skeletal muscles of zebrafish embryos. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):554-9. Epub 2008 Jan 8. |
High-throughput target validation in model organisms
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Citation:
Drug Discovery Today: TARGETS. 2004 3(5):191-7 Epub:
Not Epub Abstract:
Modern drug discovery includes a progression from the identification of molecular targets pertinent to disease processes to the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Doan TN, Eilertson CD, Rubinstein AL. High-throughput target validation in model organisms. Drug Discovery Today: TARGETS. 2004 3(5):191-7. |
HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages
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Citation:
J Clin Invest. 2003 Feb;111(3):389-97 Epub:
Not Epub Abstract:
Protease inhibitors decrease the viral load in HIV patients, however the patients develop hypertriglyceridemia,... Delivery Method:
oligo bathing Organism or Cell Type:
cell culture: THP-1 cells Citation Extract: Dressman J, Kincer J, Matveev SV, Guo L, Greenberg RN, Guerin T, Meade D, Li XA, Zhu W, Uittenbogaard A, Wilson ME, Smart EJ. HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages. J Clin Invest. 2003 Feb;111(3):389-97. |
Inhibition of brain tumor growth by intravenous poly(beta-L-malic) acid nanobioconjugate with pH-dependent drug release
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Citation:
Proc Natl Acad Sci U S A. 2010 Oct 4. [Epub ahead of print] Epub:
Not Epub Abstract:
Effective treatment of brain neurological disorders such as Alzheimer's disease, multiple sclerosis, or tumors should be... Delivery Method:
Polycefin: poly(malic acid) from Physarum polycephalum Organism or Cell Type:
mice (athymic), human glioblastoma cells U87MG Citation Extract: Ding H, Inoue S, Ljubimov AV, Patil R, Portilla-Arias J, Hu J, Konda B, Wawrowsky KA, Fujita M, Karabalin N, Sasaki T, Black KL, Holler E, Ljubimova JY. Inhibition of brain tumor growth by intravenous poly(beta-L-malic) acid nanobioconjugate with pH-dependent drug release. Proc Natl Acad Sci U S A. 2010 Oct 4. [Epub ahead of print]. |
Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown
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Citation:
Genesis. 2001 Jul;30(3):154-6 Epub:
Not Epub Abstract:
No abstract available. Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Draper BW, Morcos PA, Kimmel CB. Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown. Genesis. 2001 Jul;30(3):154-6. |
Intracardial Embryonic Delivery of Developmental Modifiers In Utero
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Citation:
Cold Spring Harb Protoc. 2012;doi:10.1101/pdb.prot069427 Epub:
Not Epub Abstract:
Our knowledge of organ ontogeny is largely based on loss-of-function (knockout) or gain-of-function (transgenesis) approaches.... Delivery Method:
Vivo-Morpholino, transplacental Organism or Cell Type:
mice Citation Extract: Domínguez-Bendala J, Álvarez-Cubela S, Nieto M, Vargas N, Espino-Grosso P, Sacher VY, Pileggi A, García E, Ricordi C, Inverardi L, Pastori RL. Intracardial Embryonic Delivery of Developmental Modifiers In Utero. Cold Spring Harb Protoc. 2012;doi:10.1101/pdb.prot069427. |
Intralineage directional Notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia
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Citation:
Neuron. 2012 Apr 12;74(1):65-78. doi: 10.1016/j.neuron.2012.01.031. Epub:
Not Epub Abstract:
Asymmetric division of progenitor/stem cells generates both self-renewing and differentiating progeny and is fundamental to... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Dong Z, Yang N, Yeo SY, Chitnis A, Guo S. Intralineage directional Notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia. Neuron. 2012 Apr 12;74(1):65-78. doi: 10.1016/j.neuron.2012.01.031.. |