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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis

Authors:
Davidson AJ, Zon LI
Citation:
Dev Biol. 2006 Apr 15;292(2):506-18. Epub 2006 Feb 7
Epub:
Not Epub
Abstract:
The hox genes play a central role in organogenesis and are implicated in the formation of hematopoietic stem cells (HSCs). The...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davidson AJ, Zon LI. The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Dev Biol. 2006 Apr 15;292(2):506-18. Epub 2006 Feb 7.

The cilia protein IFT88 is required for spindle orientation in mitosis

Authors:
Delaval B, Bright A, Lawson ND, Doxsey S
Citation:
Nat Cell Biol. 2011 Apr;13(4):461-8. Epub 2011 Mar 27
Epub:
Not Epub
Abstract:
Cilia dysfunction has long been associated with cyst formation and ciliopathies. More recently, misoriented cell division has...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Delaval B, Bright A, Lawson ND, Doxsey S. The cilia protein IFT88 is required for spindle orientation in mitosis. Nat Cell Biol. 2011 Apr;13(4):461-8. Epub 2011 Mar 27.

The glucocorticoid receptor and the orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II interact with and mutually affect each other's transcriptional activities: implications for intermediary metabolism

Authors:
De Martino MU, Bhattachryya N, Alesci S, Ichijo T, Chrousos GP, Kino T
Citation:
Mol Endocrinol. 2004 Apr;18(4):820-33. Epub 2004 Jan 22
Epub:
Not Epub
Abstract:
Glucocorticoids exert their metabolic effect via their intracellular receptor, the glucocorticoid receptor (GR). In a yeast two...
Delivery Method:
Special Delivery
Organism or Cell Type:
Cell culture: human hepatocyte HepG2
Citation Extract:
De Martino MU, Bhattachryya N, Alesci S, Ichijo T, Chrousos GP, Kino T. The glucocorticoid receptor and the orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II interact with and mutually affect each other's transcriptional activities: implications for intermediary metabolism. Mol Endocrinol. 2004 Apr;18(4):820-33. Epub 2004 Jan 22.

The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesis

Authors:
Deacon DC, Nevis KR, Cashman TJ, Zhou Y, Zhao L, Washko D, Guner-Ataman B, Burns CG, Burns CE
Citation:
Development. 2010 Jun;137(11):1887-96
Epub:
Not Epub
Abstract:
Discovering the genetic and cellular mechanisms that drive cardiac morphogenesis remains a fundamental goal, as three-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Deacon DC, Nevis KR, Cashman TJ, Zhou Y, Zhao L, Washko D, Guner-Ataman B, Burns CG, Burns CE. The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesis. Development. 2010 Jun;137(11):1887-96.

The planar polarity gene strabismus regulates convergent extension movements in Xenopus

Authors:
Darken RS, Scola AM, Rakeman AS, Das G, Mlodzik M, Wilson PA
Citation:
EMBO J. 2002 Mar; 21(5):976-985
Epub:
Not Epub
Abstract:
The signaling mechanisms that specify, guide and coordinate cell behavior during embryonic morphogenesis are poorly understood...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Darken RS, Scola AM, Rakeman AS, Das G, Mlodzik M, Wilson PA. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. EMBO J. 2002 Mar; 21(5):976-985.

Topoisomerase II-Mediated DNA Damage Is Differently Repaired during the Cell Cycle by Non-Homologous End Joining and Homologous Recombination

Authors:
de Campos-Nebel M, Larripa I, González-Cid M
Citation:
PLoS One. 2010 Sep 2;5(9). pii: e12541
Epub:
Not Epub
Abstract:
Topoisomerase II (Top2) is a nuclear enzyme involved in several metabolic processes of DNA. Chemotherapy agents that poison...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
de Campos-Nebel M, Larripa I, González-Cid M. Topoisomerase II-Mediated DNA Damage Is Differently Repaired during the Cell Cycle by Non-Homologous End Joining and Homologous Recombination. PLoS One. 2010 Sep 2;5(9). pii: e12541.

Tryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal)

Authors:
Depriest A, Phelan P, Martha Skerrett I
Citation:
Biophys J. 2011 Nov 16;101(10):2408-16. Epub 2011 Nov 15
Epub:
Not Epub
Abstract:
The channel proteins of gap junctions are encoded by two distinct gene families, connexins, which are exclusive to chordates,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Depriest A, Phelan P, Martha Skerrett I. Tryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal). Biophys J. 2011 Nov 16;101(10):2408-16. Epub 2011 Nov 15.

TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum

Authors:
Davis EE, Zhang Q, Liu Q, Diplas BH, Davey LM, Hartley J, Stoetzel C, Szymanska K, Ramaswami G, Logan CV, Muzny DM, Young AC, Wheeler DA, Cruz P, Morgan M, Lewis LR, Cherukuri P, Maskeri B, Hansen NF, Mullikin JC, Blakesley RW, Bouffard GG; NISC Comparative Sequencing Program, Gyapay G, Rieger S, Tönshoff B, Kern I, Soliman NA, Neuhaus TJ, Swoboda KJ, Kayserili H, Gallagher TE, Lewis RA, Bergmann C, Otto EA, Saunier S, Scambler PJ, Beales PL, Gleeson JG, Maher ER, Attié-Bitach T, Dollfus H, Johnson CA, Green ED, Gibbs RA, Hildebrandt F, Pierce EA, Katsanis N
Citation:
Nat Genet. 2011 Jan 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ciliary dysfunction leads to a broad range of overlapping phenotypes, collectively termed ciliopathies. This grouping is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davis EE, Zhang Q, Liu Q, Diplas BH, Davey LM, Hartley J, Stoetzel C, Szymanska K, Ramaswami G, Logan CV, Muzny DM, Young AC, Wheeler DA, Cruz P, Morgan M, Lewis LR, Cherukuri P, Maskeri B, Hansen NF, Mullikin JC, Blakesley RW, Bouffard GG; NISC Comparative Sequencing Program, Gyapay G, Rieger S, Tönshoff B, Kern I, Soliman NA, Neuhaus TJ, Swoboda KJ, Kayserili H, Gallagher TE, Lewis RA, Bergmann C, Otto EA, Saunier S, Scambler PJ, Beales PL, Gleeson JG, Maher ER, Attié-Bitach T, Dollfus H, Johnson CA, Green ED, Gibbs RA, Hildebrandt F, Pierce EA, Katsanis N. TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum. Nat Genet. 2011 Jan 23. [Epub ahead of print].

Tubulogenesis in a simple cell cord requires the formation of bi-apical cells through two discrete Par domains

Authors:
Denker E, Boccina I, Jiang D
Citation:
Development. 2013 Jun 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Apico-basal polarization is a crucial step in the de novo formation of biological tubes. In Ciona notochord, tubulogenesis...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona
Citation Extract:
Denker E, Boccina I, Jiang D. Tubulogenesis in a simple cell cord requires the formation of bi-apical cells through two discrete Par domains. Development. 2013 Jun 12. [Epub ahead of print].

Vascular cell adhesion molecule 1 (VCAM-1) activation of endothelial cell matrix metalloproteinases: role of reactive oxygen species

Authors:
Deem TL, Cook-Mills JM
Citation:
Blood. 2004 Oct 15;104(8):2385-93. Epub 2004 Jul 20
Epub:
Not Epub
Abstract:
Lymphocytes bound at endothelial cell junctions extravasate within minutes. Lymphocyte-endothelial cell binding is mediated by...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: mouse mHEVc
Citation Extract:
Deem TL, Cook-Mills JM. Vascular cell adhesion molecule 1 (VCAM-1) activation of endothelial cell matrix metalloproteinases: role of reactive oxygen species. Blood. 2004 Oct 15;104(8):2385-93. Epub 2004 Jul 20.

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