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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle

Authors:
Dutton K, Abbas L, Spencer J, Brannon C, Mowbray C, Nikaido M, Kelsh RN, Whitfield TT
Citation:
Dis Model Mech. 2009 Jan;2(1-2):68-83. Epub 2008 Dec 22
Epub:
Not Epub
Abstract:
In humans, mutations in the SOX10 gene are a cause of the auditory-pigmentary disorder Waardenburg syndrome type IV (WS4) and...
Organism or Cell Type:
zebrafish
Citation Extract:
Dutton K, Abbas L, Spencer J, Brannon C, Mowbray C, Nikaido M, Kelsh RN, Whitfield TT. A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle. Dis Model Mech. 2009 Jan;2(1-2):68-83. Epub 2008 Dec 22.

Actinotrichia collagens and their role in fin formation

Authors:
Durán I, Marí-Beffa M, Santamaría JA, Becerra J, Santos-Ruiz L
Citation:
Dev Biol. 2011 Mar 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The skeleton of zebrafish fins consists of lepidotrichia and actinotrichia. Actinotrichia are fibrils located at the tip of...
Organism or Cell Type:
zebrafish
Citation Extract:
Durán I, Marí-Beffa M, Santamaría JA, Becerra J, Santos-Ruiz L. Actinotrichia collagens and their role in fin formation. Dev Biol. 2011 Mar 17. [Epub ahead of print].

Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum

Authors:
Du L, Kayali R, Bertoni C, Fike F, Hu H, Iversen PL, Gatti RA
Citation:
Hum Mol Genet. 2011 May 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense morpholino oligonucleotides (AMOs) can reprogram pre-mRNA splicing by complementarily binding to a target site and...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice
Citation Extract:
Du L, Kayali R, Bertoni C, Fike F, Hu H, Iversen PL, Gatti RA. Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum. Hum Mol Genet. 2011 May 16. [Epub ahead of print].

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation

Authors:
Ding Y, Xi Y, Chen T, Wang JY, Tao DL, Wu ZL, Li YP, Li C, Zeng R, Li L
Citation:
J Cell Biol. 2008 Sep 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The low-density lipoprotein receptor-related proteins 5 and 6 (LRP5/6) are coreceptors for Frizzled and transmit signals from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ding Y, Xi Y, Chen T, Wang JY, Tao DL, Wu ZL, Li YP, Li C, Zeng R, Li L. Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation. J Cell Biol. 2008 Sep 1. [Epub ahead of print].

Carboxypeptidase A5 identifies a novel mast cell lineage in the zebrafish providing new insight into mast cell fate determination

Authors:
Dobson JT, Seibert J, Teh EM, Daas S, Fraser RB, Paw BH, Lin TJ, Berman JN
Citation:
Blood. 2008 Jul 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mast cells (MCs) play critical roles in allergy and inflammation, yet their development remains controversial due to...
Organism or Cell Type:
zebrafish
Citation Extract:
Dobson JT, Seibert J, Teh EM, Daas S, Fraser RB, Paw BH, Lin TJ, Berman JN. Carboxypeptidase A5 identifies a novel mast cell lineage in the zebrafish providing new insight into mast cell fate determination. Blood. 2008 Jul 17. [Epub ahead of print].

Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion

Authors:
Duldulao NA, Lee S, Sun Z
Citation:
Development. 2009 Dec;136(23):4033-42
Epub:
Not Epub
Abstract:
arl13b was initially cloned as the novel cystic kidney gene scorpion (sco) in zebrafish and was shown to be required for cilia...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Duldulao NA, Lee S, Sun Z. Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion. Development. 2009 Dec;136(23):4033-42.

Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts

Authors:
Dumortier JG, Martin S, Meyer D, Rosa FM, David NB
Citation:
Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16945-50. doi: 10.1073/pnas.1205870109. Epub 2012 Oct 1
Epub:
Not Epub
Abstract:
Collective cell migration is key to morphogenesis, wound healing, or cancer cell migration. However, its cellular bases are...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dumortier JG, Martin S, Meyer D, Rosa FM, David NB. Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16945-50. doi: 10.1073/pnas.1205870109. Epub 2012 Oct 1.

Control of Directed Cell Migration In Vivo by Membrane-to-Cortex Attachment

Authors:
Diz-Muñoz A, Krieg M, Bergert M, Ibarlucea-Benitez I, Muller DJ, Paluch E, Heisenberg CP
Citation:
PLoS Biol. 2010;8(11):e1000544. doi:10.1371/journal.pbio.1000544
Epub:
Not Epub
Abstract:
Cell shape and motility are primarily controlled by cellular mechanics. The attachment of the plasma membrane to the underlying...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Diz-Muñoz A, Krieg M, Bergert M, Ibarlucea-Benitez I, Muller DJ, Paluch E, Heisenberg CP. Control of Directed Cell Migration In Vivo by Membrane-to-Cortex Attachment. PLoS Biol. 2010;8(11):e1000544. doi:10.1371/journal.pbio.1000544.

Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids

Authors:
Duffy KT, McAleer MF, Davidson WR, Kari L, Kari C, Liu CG, Farber SA, Cheng KC, Mest JR, Wickstrom E, Dicker AP, Rodeck U
Citation:
Nucleic Acids Res. 2005 Sep 2;33(15):4914-21. Print 2005
Epub:
Not Epub
Abstract:
During early zebrafish (Danio rerio) development zygotic transcription does not begin until the mid-blastula transition (MBT) 3...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Duffy KT, McAleer MF, Davidson WR, Kari L, Kari C, Liu CG, Farber SA, Cheng KC, Mest JR, Wickstrom E, Dicker AP, Rodeck U. Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids. Nucleic Acids Res. 2005 Sep 2;33(15):4914-21. Print 2005.

Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides

Authors:
Du L, Pollard JM, Gatti RA
Citation:
Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6007-12. Epub 2007 Mar 26.
Epub:
Not Epub
Abstract:
We used antisense morpholino oligonucleotides (AMOs) to redirect and restore normal splicing of three prototypic splicing...
Citation Extract:
Du L, Pollard JM, Gatti RA. Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6007-12. Epub 2007 Mar 26..

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