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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

MicroRNAs are essential for development and function of inner ear hair cells in vertebrates

Authors:
Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB
Citation:
Proc Natl Acad Sci U S A. 2009 Apr 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) inhibit the translation of target mRNAs and affect, directly or indirectly, the expression of a large...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB. MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 Apr 28. [Epub ahead of print] .

miR-126 regulates angiogenic signaling and vascular integrity

Authors:
Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D
Citation:
Dev Cell. 2008 Aug;15(2):272-84
Epub:
Not Epub
Abstract:
Precise regulation of the formation, maintenance, and remodeling of the vasculature is required for normal development, tissue...
Organism or Cell Type:
zebrafish
Citation Extract:
Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D. miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell. 2008 Aug;15(2):272-84.

miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos

Authors:
Flynt AS, Thatcher EJ, Burkewitz K, Li N, Liu Y, Patton JG
Citation:
J Cell Biol. 2009 Mar 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are highly conserved small RNAs that act as translational regulators of gene expression, exerting their...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Flynt AS, Thatcher EJ, Burkewitz K, Li N, Liu Y, Patton JG. miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos. J Cell Biol. 2009 Mar 30. [Epub ahead of print].

Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching

Authors:
Fragall CT, Adams AM, Johnsen RD, Kole R, Fletcher S, Wilton SD
Citation:
BMC Med Genet. 2011 Oct 20;12(1):141. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Antisense oligomer induced exon skipping aims to reduce the severity of Duchenne muscular dystrophy by redirecting...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: human myoblasts from fibroblasts
Citation Extract:
Fragall CT, Adams AM, Johnsen RD, Kole R, Fletcher S, Wilton SD. Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching. BMC Med Genet. 2011 Oct 20;12(1):141. [Epub ahead of print].

Modulation of total Akt kinase by increased expression of a single isoform: requirement of the sphingosine-1-phosphate receptor, Edg3/S1P3, for the VEGF-dependent expression of Akt3 in primary endothelial cells.

Authors:
Fieber CB, Eldridge J, Taha TA, Obeid LM, Muise-Helmericks RC.
Citation:
Exp Cell Res. 2006 Apr 15;312(7):1164-73. Epub 2006 Mar 9
Epub:
Not Epub
Abstract:
Akt kinase is an important downstream effector of VEGF in primary endothelial cells (EC), promoting angiogenesis by increased...
Delivery Method:
transfection
Organism or Cell Type:
Cell Culture: human umbilical vein endothelial cells (HUVECs)
Citation Extract:
Fieber CB, Eldridge J, Taha TA, Obeid LM, Muise-Helmericks RC.. Modulation of total Akt kinase by increased expression of a single isoform: requirement of the sphingosine-1-phosphate receptor, Edg3/S1P3, for the VEGF-dependent expression of Akt3 in primary endothelial cells.. Exp Cell Res. 2006 Apr 15;312(7):1164-73. Epub 2006 Mar 9.

Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle

Authors:
Fletcher S, Gebski BL, Mann CJ, Wilton SD
Citation:
Hum Mol Genet. 2003 Aug 1;12(15):1801-11
Epub:
Not Epub
Abstract:
The mdx mouse model of muscular dystrophy arose due to a nonsense mutation in exon 23 of the dystrophin gene. We have...
Delivery Method:
cationic lipoplex: a number of leash designs and chemistries
Organism or Cell Type:
mdx mice, cell culture: mdx
Citation Extract:
Fletcher S, Gebski BL, Mann CJ, Wilton SD. Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle. Hum Mol Genet. 2003 Aug 1;12(15):1801-11.

Morpholino Oligomer-Mediated Exon Skipping Averts the Onset of Dystrophic Pathology in the mdx Mouse

Authors:
Fletcher S, Honeyman K, Fall AM, Harding PL, Johnsen RD, Steinhaus JP, Moulton HM, Iversen PL, Wilton SD
Citation:
Mol Ther. 2007 Sep;15(9):1587-92. Epub 2007 Jun 19.
Epub:
Not Epub
Abstract:
Duchenne and Becker muscular dystrophies are allelic disorders arising from mutations in the dystrophin gene. Duchenne muscular...
Delivery Method:
peptide-coupled
Organism or Cell Type:
MDX mice
Citation Extract:
Fletcher S, Honeyman K, Fall AM, Harding PL, Johnsen RD, Steinhaus JP, Moulton HM, Iversen PL, Wilton SD. Morpholino Oligomer-Mediated Exon Skipping Averts the Onset of Dystrophic Pathology in the mdx Mouse. Mol Ther. 2007 Sep;15(9):1587-92. Epub 2007 Jun 19..

Morpholino phenocopies of sqt, oep, and ntl mutations

Authors:
Feldman B, Stemple DL
Citation:
Genesis. 2001 Jul;30(3):175-7
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feldman B, Stemple DL. Morpholino phenocopies of sqt, oep, and ntl mutations. Genesis. 2001 Jul;30(3):175-7.

Multiple functions of Cerberus cooperate to induce heart downstream of Nodal

Authors:
Foley AC, Korol O, Timmer AM, Mercola M
Citation:
Dev Biol. 2007 Mar 1;303(1):57-65. Epub 2006 Oct 26.
Epub:
Not Epub
Abstract:
The TGFbeta family member Nodal has been implicated in heart induction through misexpression of a dominant negative version of...
Organism or Cell Type:
Xenopus
Citation Extract:
Foley AC, Korol O, Timmer AM, Mercola M. Multiple functions of Cerberus cooperate to induce heart downstream of Nodal. Dev Biol. 2007 Mar 1;303(1):57-65. Epub 2006 Oct 26..

Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease

Authors:
Friedrich T, Lambert AM, Masino MA, Downes GB
Citation:
Dis Model Mech. 2012 Mar;5(2):248-58. Epub 2011 Nov 1
Epub:
Not Epub
Abstract:
Analysis of zebrafish mutants that demonstrate abnormal locomotive behavior can elucidate the molecular requirements for neural...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Friedrich T, Lambert AM, Masino MA, Downes GB. Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease. Dis Model Mech. 2012 Mar;5(2):248-58. Epub 2011 Nov 1.

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