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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish

Authors:
Epting D, Wendik B, Bennewitz K, Dietz CT, Driever W, Kroll J
Citation:
Circ Res. 2010 Jul 9;107(1):45-55. doi: 10.1161/CIRCRESAHA.109.213983. Epub 2010 May 13
Epub:
Not Epub
Abstract:
Rationale: Angiogenesis is regulated by the small GTPase Rac1. The ELMO1/DOCK180 complex forms a guanine nucleotide exchange...
Organism or Cell Type:
zebrafish
Citation Extract:
Epting D, Wendik B, Bennewitz K, Dietz CT, Driever W, Kroll J. The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish. Circ Res. 2010 Jul 9;107(1):45-55. doi: 10.1161/CIRCRESAHA.109.213983. Epub 2010 May 13.

The role of the ETS factor erg in zebrafish vasculogenesis

Authors:
Ellett F, Kile BT, Lieschke GJ
Citation:
Mech Dev. 2008 Nov 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Erg, a member of the ETS family of transcription factors, has been implicated by previous studies in endothelial and...
Organism or Cell Type:
zebrafish
Citation Extract:
Ellett F, Kile BT, Lieschke GJ. The role of the ETS factor erg in zebrafish vasculogenesis. Mech Dev. 2008 Nov 8. [Epub ahead of print].

The use of in vivo zebrafish assays in drug toxicity screening

Authors:
Eimon PM, Rubinstein AL
Citation:
Expert Opin Drug Metab Toxicol. 2009 Apr;5(4):393-401
Epub:
Not Epub
Abstract:
Anecdotal evidence has long suggested that zebrafish may be a good model to predict toxicity of human drugs. As summarized in...
Organism or Cell Type:
zebrafish
Citation Extract:
Eimon PM, Rubinstein AL. The use of in vivo zebrafish assays in drug toxicity screening. Expert Opin Drug Metab Toxicol. 2009 Apr;5(4):393-401.

TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3

Authors:
Espín R, Roca FJ, Candel S, Sepulcre MP, González-Rosa JM, Alcaraz-Pérez F, Meseguer J, Cayuela ML, Mercader N, Mulero V
Citation:
Dis Model Mech. 2013;6(2):383-96. doi:10.1242/dmm.010249
Epub:
Not Epub
Abstract:
Although it is known that tumor necrosis factor receptor (TNFR) signaling plays a crucial role in vascular integrity and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Espín R, Roca FJ, Candel S, Sepulcre MP, González-Rosa JM, Alcaraz-Pérez F, Meseguer J, Cayuela ML, Mercader N, Mulero V. TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3. Dis Model Mech. 2013;6(2):383-96. doi:10.1242/dmm.010249.

trpm7 Regulation of in Vivo Cation Homeostasis and Kidney Function Involves Stanniocalcin 1 and fgf23

Authors:
Elizondo MR, Budi EH, Parichy DM
Citation:
Endocrinology. 2010 Sep 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The transient receptor potential melastatin 7 (trpm7) channel kinase is a primary regulator of magnesium homeostasis in vitro....
Organism or Cell Type:
zebrafish
Citation Extract:
Elizondo MR, Budi EH, Parichy DM. trpm7 Regulation of in Vivo Cation Homeostasis and Kidney Function Involves Stanniocalcin 1 and fgf23. Endocrinology. 2010 Sep 29. [Epub ahead of print].

Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination

Authors:
Esguerra CV, Nelles L, Vermeire L, Ibrahimi A, Crawford AD, Derua R, Janssens E, Waelkens E, Carmeliet P, Collen D, Huylebroeck D
Citation:
Development. 2007 Dec;134(24):4381-93
Epub:
Not Epub
Abstract:
During vertebrate development, signaling by the TGFbeta ligand Nodal is critical for mesoderm formation, correct positioning of...
Organism or Cell Type:
zebrafish
Citation Extract:
Esguerra CV, Nelles L, Vermeire L, Ibrahimi A, Crawford AD, Derua R, Janssens E, Waelkens E, Carmeliet P, Collen D, Huylebroeck D. Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination. Development. 2007 Dec;134(24):4381-93.

Vertebrate development requires ARVCF and p120 catenins and their interplay with RhoA and Rac

Authors:
Fang X, Ji H, Kim SW, Park JI, Vaught TG, Anastasiadis PZ, Ciesiolka M, McCrea PD
Citation:
J Cell Biol. 2004 Apr 12;165(1):87-98.
Epub:
Not Epub
Abstract:
Using an animal model system and depletion-rescue strategies, we have addressed the requirement and functions of armadillo...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Fang X, Ji H, Kim SW, Park JI, Vaught TG, Anastasiadis PZ, Ciesiolka M, McCrea PD. Vertebrate development requires ARVCF and p120 catenins and their interplay with RhoA and Rac. J Cell Biol. 2004 Apr 12;165(1):87-98..

Visualization in zebrafish larvae of Na+ uptake in mitochondrion-rich cells whose differentiation is dependent on foxi3alpha

Authors:
Esaki M, Hoshijima K, Kobayashi S, Fukuda H, Kawakami K, Hirose S
Citation:
Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R470-80. Epub 2006 Aug 31.
Epub:
Not Epub
Abstract:
Uptake of Na(+) from the environment is an indispensable strategy for the survival of freshwater fish, as they easily lose Na...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Esaki M, Hoshijima K, Kobayashi S, Fukuda H, Kawakami K, Hirose S. Visualization in zebrafish larvae of Na+ uptake in mitochondrion-rich cells whose differentiation is dependent on foxi3alpha. Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R470-80. Epub 2006 Aug 31..

VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in Mice

Authors:
Enterlein S, Warfield KL, Swenson DL, Stein DA, Smith JL, Gamble CS, Kroeker AD, Iversen PL, Bavari S, Muhlberger E
Citation:
Antimicrob Agents Chemother. 2006 Mar;50(3):984-93
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMO) are a class of uncharged single-stranded DNA analogs modified such that each...
Link:
http://aac.asm.org/content/50/3/984.abstract
Delivery Method:
Peptide-coupled and oligo bathing
Organism or Cell Type:
mice and cell culture
Citation Extract:
Enterlein S, Warfield KL, Swenson DL, Stein DA, Smith JL, Gamble CS, Kroeker AD, Iversen PL, Bavari S, Muhlberger E. VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in Mice. Antimicrob Agents Chemother. 2006 Mar;50(3):984-93.

Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo

Authors:
Erter CE, Wilm TP, Basler N, Wright CV, Solnica-Krezel L
Citation:
Development. 2001 Sep;128(18):3571-83
Epub:
Not Epub
Abstract:
The dorsal ectoderm of the vertebrate gastrula was proposed by Nieuwkoop to be specified towards an anterior neural fate by an...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Erter CE, Wilm TP, Basler N, Wright CV, Solnica-Krezel L. Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo. Development. 2001 Sep;128(18):3571-83.

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