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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
scn1bb, a Zebrafish Ortholog of SCN1B Expressed in Excitable and Nonexcitable Cells, Affects Motor Neuron Axon Morphology and Touch Sensitivity
Citation:
J Neurosci. 2008 Nov 19;28(47):12510-12522 Epub:
Not Epub Abstract:
Voltage-gated Na(+) channels initiate and propagate action potentials in excitable cells. Mammalian Na(+) channels are composed... Organism or Cell Type:
zebrafish Citation Extract: Fein AJ, Wright MA, Slat EA, Ribera AB, Isom LL. scn1bb, a Zebrafish Ortholog of SCN1B Expressed in Excitable and Nonexcitable Cells, Affects Motor Neuron Axon Morphology and Touch Sensitivity. J Neurosci. 2008 Nov 19;28(47):12510-12522. |
Site-specific DICER and DROSHA RNA products control the DNA-damage response
Citation:
Nature. 2012;[epub ahead of print] doi:10.1038/nature11179 Epub:
Not Epub Abstract:
Non-coding RNAs (ncRNAs) are involved in an increasingly recognized number of cellular events. Some ncRNAs are processed by... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, Mione M, Carninci P, d’Adda di Fagagna F. Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature. 2012;[epub ahead of print] doi:10.1038/nature11179. |
Subfunctionalization of a retinoid-binding protein provides evidence for two parallel visual cycles in the cone-dominant zebrafish retina
Citation:
J Neurosci. 2008 Aug 13;28(33):8208-16 Epub:
Not Epub Abstract:
In vertebrates, the absorption of a photon results in an 11-cis to all-trans isomerization of the retinylidene chromophore of... Organism or Cell Type:
zebrafish Citation Extract: Fleisch VC, Schonthaler HB, von Lintig J, Neuhauss SC. Subfunctionalization of a retinoid-binding protein provides evidence for two parallel visual cycles in the cone-dominant zebrafish retina. J Neurosci. 2008 Aug 13;28(33):8208-16. |
Targeted Exon Skipping to Address \"Leaky\" Mutations in the Dystrophin Gene
Citation:
Mol Ther Nucleic Acids. 2012;1:e48 doi:/10.1038/mtna.2012.40 Epub:
Not Epub Abstract:
Protein-truncating mutations in the dystrophin gene lead to the progressive muscle wasting disorder Duchenne muscular dystrophy... Delivery Method:
peptide-coupled in mice, elecytroporation in cell culture Organism or Cell Type:
mice Citation Extract: Fletcher S, Adkin CF, Meloni P, Wong B, Muntoni F, Kole R, Fragall C, Greer K, Johnsen R, Wilton SD. Targeted Exon Skipping to Address \"Leaky\" Mutations in the Dystrophin Gene. Mol Ther Nucleic Acids. 2012;1:e48 doi:/10.1038/mtna.2012.40. |
The activation of membrane targeted CaMK-II in the zebrafish Kupffer's vesicle is required for left-right asymmetry
Citation:
Development. 2010 Jul 14. [Epub ahead of print] Epub:
Not Epub Abstract:
Intracellular calcium ion (Ca(2+)) elevation on the left side of the mouse embryonic node or zebrafish Kupffer's vesicle (... Organism or Cell Type:
zebrafish Citation Extract: Francescatto L, Rothschild SC, Myers AL, Tombes RM. The activation of membrane targeted CaMK-II in the zebrafish Kupffer's vesicle is required for left-right asymmetry. Development. 2010 Jul 14. [Epub ahead of print]. |
The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord
Citation:
Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4377-82. Epub:
Not Epub Abstract:
olig genes encode a previously unrecognized group of vertebrate-specific basic helix-loop-helix transcription factors. As shown... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Filippi A, Tiso N, Deflorian G, Zecchin E, Bortolussi M, Argenton F. The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4377-82.. |
The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes
Citation:
PLoS Genet. 2011;7(4): e1001361. doi:10.1371/journal.pgen.1001361 Epub:
Not Epub Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by formation of renal cysts that destroy the kidney.... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Fogelgren B, Lin S-Y, Zuo X, Jaffe KM, Park KM, Reichert RJ, Bell PD, Burdine RD, Lipschutz JH. The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes. PLoS Genet. 2011;7(4): e1001361. doi:10.1371/journal.pgen.1001361. |
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation
Citation:
EMBO J. 2007 Sep 19;26(18):4138-48. Epub 2007 Aug 30 Epub:
Not Epub Abstract:
Monocyte differentiation involves the participation of lineage-restricted transcription factors, although the mechanisms by... Organism or Cell Type:
cell culture: HL60 cells Citation Extract: Feinberg MW, Wara AK, Cao Z, Lebedeva MA, Rosenbauer F, Iwasaki H, Hirai H, Katz JP, Haspel RL, Gray S, Akashi K, Segre J, Kaestner KH, Tenen DG, Jain MK. The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. EMBO J. 2007 Sep 19;26(18):4138-48. Epub 2007 Aug 30. |
The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via Sirtuin1-mediated inactivation of FOXO1
Citation:
Am J Physiol Gastrointest Liver Physiol. 2012 Oct 18. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: Progranulin (PGRN), a secreted growth factor, regulates the proliferation of various epithelial cells. Its... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Frampton G, Ueno Y, Quinn M, McMillin M, Pae HY, Galindo C, Leyva-Illades D, Demorrow S. The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via Sirtuin1-mediated inactivation of FOXO1. Am J Physiol Gastrointest Liver Physiol. 2012 Oct 18. [Epub ahead of print]. |
The proneural bHLH gene ascl1a is required for retina regeneration
Citation:
J Neurosci. 2008 Jan 30;28(5):1109-17 Epub:
Not Epub Abstract:
Unlike mammals, teleost fish can regenerate an injured retina, restoring lost visual function. Little is known of the molecular... Organism or Cell Type:
zebrafish Citation Extract: Fausett BV, Gumerson JD, Goldman D. The proneural bHLH gene ascl1a is required for retina regeneration. J Neurosci. 2008 Jan 30;28(5):1109-17. |