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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
A role for GATA factors in Xenopus gastrulation movements
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Citation:
Mech Dev. 2006 Oct;123(10):730-45. Epub 2006 Jul 26. Epub:
Not Epub Abstract:
Gastrulation movements in Xenopus laevis are becoming increasingly well characterised, however the molecular mechanisms... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Fletcher G, Jones GE, Patient R, Snape A. A role for GATA factors in Xenopus gastrulation movements. Mech Dev. 2006 Oct;123(10):730-45. Epub 2006 Jul 26.. |
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish
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Citation:
Development. 2011 Apr;138(7):1409-19 Epub:
Not Epub Abstract:
Members of the Slit family of secreted ligands interact with Roundabout (Robo) receptors to provide guidance cues for many cell... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development. 2011 Apr;138(7):1409-19. |
A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway
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Citation:
Development. 2012 Jul;139(13):2416-25. doi: 10.1242/dev.063206 Epub:
Not Epub Abstract:
Multiple developmental processes require tightly controlled Wnt signaling, and its misregulation leads to congenital... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Flowers GP, Topczewska JM, Topczewski J. A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway. Development. 2012 Jul;139(13):2416-25. doi: 10.1242/dev.063206. |
Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos
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Citation:
BMC Biol. 2013 Jun 17;11:69. doi: 10.1186/1741-7007-11-69. PMID: 23773777; PMCID: PMC3765700 Epub:
Not Epub Abstract:
BACKGROUND: In mammals, ABCB1 constitutes a cellular \"first line of defense\" against a wide array of chemicals and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fischer S, Klüver N, Burkhardt-Medicke K, Pietsch M, Schmidt AM, Wellner P, Schirmer K, Luckenbach T. Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos. BMC Biol. 2013 Jun 17;11:69. doi: 10.1186/1741-7007-11-69. PMID: 23773777; PMCID: PMC3765700. |
Altered Chondrocyte Differentiation and Extracellular Matrix Homeostasis in a Zebrafish Model for Mucolipidosis II
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Citation:
Am J Pathol. 2009 Oct 15. [Epub ahead of print] Epub:
Not Epub Abstract:
Mucolipidosis II (ML-II) is a pediatric disorder caused by defects in the biosynthesis of mannose 6-phosphate, the carbohydrate... Organism or Cell Type:
zebrafish Citation Extract: Flanagan-Steet H, Sias C, Steet R. Altered Chondrocyte Differentiation and Extracellular Matrix Homeostasis in a Zebrafish Model for Mucolipidosis II. Am J Pathol. 2009 Oct 15. [Epub ahead of print]. |
An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases
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Citation:
BMC Mol Biol. 2012;13:6 doi:10.1186/1471-2199-13-6 Epub:
Not Epub Abstract:
RNA interference (RNAi) and antisense strategies provide experimental therapeutic agents for numerous diseases, including... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary human fibroblasts, Huntington disease Citation Extract: Fiszer A, Olejniczak M, Switonski PM, Wroblewska JP, Wisniewska-Kruk JW, Mykowska A, Krzyzosiak WJ. An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases. BMC Mol Biol. 2012;13:6 doi:10.1186/1471-2199-13-6. |
Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish
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Citation:
Neurogastroenterol Motil. 2009 Mar;21(3):304-12. Epub 2008 Dec 31 Epub:
Not Epub Abstract:
Gastrointestinal function depends upon coordinated contractions to mix and propel food through the gut. Deregulation of these... Organism or Cell Type:
zebrafish Citation Extract: Field HA, Kelley KA, Martell L, Goldstein AM, Serluca FC. Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish. Neurogastroenterol Motil. 2009 Mar;21(3):304-12. Epub 2008 Dec 31. |
Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development
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Citation:
Dev Biol. 2012 Jun 20. [Epub ahead of print] Epub:
Not Epub Abstract:
Distinct groups of dopaminergic neurons develop at defined anatomical sites in the brain to modulate function of a large... Organism or Cell Type:
zebrafish Citation Extract: Filippi A, Jainok C, Driever W. Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development. Dev Biol. 2012 Jun 20. [Epub ahead of print]. |
Anti-infectives: Post-exposure antisense protection against lethal filoviruses?
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Citation:
Nat Rev Drug Discov. 2010 Oct;9(10):764-5 Epub:
Not Epub Abstract:
No abstract available. Delivery Method:
PMO+ Citation Extract: Flemming A. Anti-infectives: Post-exposure antisense protection against lethal filoviruses?. Nat Rev Drug Discov. 2010 Oct;9(10):764-5. |
Antisense suppression of donor splice site mutations in the dystrophin gene transcript
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Citation:
Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13. PMID: 24498612; PMCID: PMC3865583 Epub:
Not Epub Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: human primary fibroblasts and myogenic cells (subsequently differentiated) Citation Extract: Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13. PMID: 24498612; PMCID: PMC3865583. |