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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Targeted Exon Skipping to Address \"Leaky\" Mutations in the Dystrophin Gene
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Citation:
Mol Ther Nucleic Acids. 2012;1:e48 doi:/10.1038/mtna.2012.40 Epub:
Not Epub Abstract:
Protein-truncating mutations in the dystrophin gene lead to the progressive muscle wasting disorder Duchenne muscular dystrophy... Delivery Method:
peptide-coupled in mice, elecytroporation in cell culture Organism or Cell Type:
mice Citation Extract: Fletcher S, Adkin CF, Meloni P, Wong B, Muntoni F, Kole R, Fragall C, Greer K, Johnsen R, Wilton SD. Targeted Exon Skipping to Address \"Leaky\" Mutations in the Dystrophin Gene. Mol Ther Nucleic Acids. 2012;1:e48 doi:/10.1038/mtna.2012.40. |
The activation of membrane targeted CaMK-II in the zebrafish Kupffer's vesicle is required for left-right asymmetry
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Citation:
Development. 2010 Jul 14. [Epub ahead of print] Epub:
Not Epub Abstract:
Intracellular calcium ion (Ca(2+)) elevation on the left side of the mouse embryonic node or zebrafish Kupffer's vesicle (... Organism or Cell Type:
zebrafish Citation Extract: Francescatto L, Rothschild SC, Myers AL, Tombes RM. The activation of membrane targeted CaMK-II in the zebrafish Kupffer's vesicle is required for left-right asymmetry. Development. 2010 Jul 14. [Epub ahead of print]. |
The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord
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Citation:
Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4377-82. Epub:
Not Epub Abstract:
olig genes encode a previously unrecognized group of vertebrate-specific basic helix-loop-helix transcription factors. As shown... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Filippi A, Tiso N, Deflorian G, Zecchin E, Bortolussi M, Argenton F. The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4377-82.. |
The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes
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Citation:
PLoS Genet. 2011;7(4): e1001361. doi:10.1371/journal.pgen.1001361 Epub:
Not Epub Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by formation of renal cysts that destroy the kidney.... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Fogelgren B, Lin S-Y, Zuo X, Jaffe KM, Park KM, Reichert RJ, Bell PD, Burdine RD, Lipschutz JH. The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes. PLoS Genet. 2011;7(4): e1001361. doi:10.1371/journal.pgen.1001361. |
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation
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Citation:
EMBO J. 2007 Sep 19;26(18):4138-48. Epub 2007 Aug 30 Epub:
Not Epub Abstract:
Monocyte differentiation involves the participation of lineage-restricted transcription factors, although the mechanisms by... Organism or Cell Type:
cell culture: HL60 cells Citation Extract: Feinberg MW, Wara AK, Cao Z, Lebedeva MA, Rosenbauer F, Iwasaki H, Hirai H, Katz JP, Haspel RL, Gray S, Akashi K, Segre J, Kaestner KH, Tenen DG, Jain MK. The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. EMBO J. 2007 Sep 19;26(18):4138-48. Epub 2007 Aug 30. |
The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via Sirtuin1-mediated inactivation of FOXO1
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Citation:
Am J Physiol Gastrointest Liver Physiol. 2012 Oct 18. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: Progranulin (PGRN), a secreted growth factor, regulates the proliferation of various epithelial cells. Its... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Frampton G, Ueno Y, Quinn M, McMillin M, Pae HY, Galindo C, Leyva-Illades D, Demorrow S. The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via Sirtuin1-mediated inactivation of FOXO1. Am J Physiol Gastrointest Liver Physiol. 2012 Oct 18. [Epub ahead of print]. |
The proneural bHLH gene ascl1a is required for retina regeneration
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Citation:
J Neurosci. 2008 Jan 30;28(5):1109-17 Epub:
Not Epub Abstract:
Unlike mammals, teleost fish can regenerate an injured retina, restoring lost visual function. Little is known of the molecular... Organism or Cell Type:
zebrafish Citation Extract: Fausett BV, Gumerson JD, Goldman D. The proneural bHLH gene ascl1a is required for retina regeneration. J Neurosci. 2008 Jan 30;28(5):1109-17. |
The recombination activation gene 1 (Rag1) is expressed in a subset of zebrafish olfactory neurons but is not essential for axon targeting or amino acid detection
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Citation:
BMC Neurosci. 2005 Jul 15;6:46. Epub:
Not Epub Abstract:
BACKGROUND: Rag1 (Recombination activation gene-1) mediates genomic rearrangement and is essential for adaptive immunity in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Feng B, Bulchand S, Yaksi E, Friedrich RW, Jesuthasan SJ. The recombination activation gene 1 (Rag1) is expressed in a subset of zebrafish olfactory neurons but is not essential for axon targeting or amino acid detection. BMC Neurosci. 2005 Jul 15;6:46.. |
The role of CYP1A inhibition in the embryotoxic interactions between hypoxia and polycyclic aromatic hydrocarbons (PAHs) and PAH mixtures in zebrafish (Danio rerio)
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Citation:
Ecotoxicology. 2011 Jun 26. [Epub ahead of print] Epub:
Not Epub Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants with elevated concentrations in waters that may... Organism or Cell Type:
zebrafish Citation Extract: Fleming CR, Di Giulio RT. The role of CYP1A inhibition in the embryotoxic interactions between hypoxia and polycyclic aromatic hydrocarbons (PAHs) and PAH mixtures in zebrafish (Danio rerio). Ecotoxicology. 2011 Jun 26. [Epub ahead of print]. |
The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus
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Citation:
Dev Dyn. 2008 May;237(5):1243-54 Epub:
Not Epub Abstract:
FGF signaling is important for the formation of mesoderm in vertebrates, and when it is perturbed in Xenopus, most trunk and... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Fletcher RB, Harland RM. The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus. Dev Dyn. 2008 May;237(5):1243-54. |