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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching
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Citation:
BMC Med Genet. 2011 Oct 20;12(1):141. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: Antisense oligomer induced exon skipping aims to reduce the severity of Duchenne muscular dystrophy by redirecting... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: human myoblasts from fibroblasts Citation Extract: Fragall CT, Adams AM, Johnsen RD, Kole R, Fletcher S, Wilton SD. Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching. BMC Med Genet. 2011 Oct 20;12(1):141. [Epub ahead of print]. |
Modulation of total Akt kinase by increased expression of a single isoform: requirement of the sphingosine-1-phosphate receptor, Edg3/S1P3, for the VEGF-dependent expression of Akt3 in primary endothelial cells.
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Citation:
Exp Cell Res. 2006 Apr 15;312(7):1164-73. Epub 2006 Mar 9 Epub:
Not Epub Abstract:
Akt kinase is an important downstream effector of VEGF in primary endothelial cells (EC), promoting angiogenesis by increased... Delivery Method:
transfection Organism or Cell Type:
Cell Culture: human umbilical vein endothelial cells (HUVECs) Citation Extract: Fieber CB, Eldridge J, Taha TA, Obeid LM, Muise-Helmericks RC.. Modulation of total Akt kinase by increased expression of a single isoform: requirement of the sphingosine-1-phosphate receptor, Edg3/S1P3, for the VEGF-dependent expression of Akt3 in primary endothelial cells.. Exp Cell Res. 2006 Apr 15;312(7):1164-73. Epub 2006 Mar 9. |
Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle
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Citation:
Hum Mol Genet. 2003 Aug 1;12(15):1801-11 Epub:
Not Epub Abstract:
The mdx mouse model of muscular dystrophy arose due to a nonsense mutation in exon 23 of the dystrophin gene. We have... Delivery Method:
cationic lipoplex: a number of leash designs and chemistries Organism or Cell Type:
mdx mice, cell culture: mdx Citation Extract: Fletcher S, Gebski BL, Mann CJ, Wilton SD. Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle. Hum Mol Genet. 2003 Aug 1;12(15):1801-11. |
Morpholino Oligomer-Mediated Exon Skipping Averts the Onset of Dystrophic Pathology in the mdx Mouse
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Citation:
Mol Ther. 2007 Sep;15(9):1587-92. Epub 2007 Jun 19. Epub:
Not Epub Abstract:
Duchenne and Becker muscular dystrophies are allelic disorders arising from mutations in the dystrophin gene. Duchenne muscular... Delivery Method:
peptide-coupled Organism or Cell Type:
MDX mice Citation Extract: Fletcher S, Honeyman K, Fall AM, Harding PL, Johnsen RD, Steinhaus JP, Moulton HM, Iversen PL, Wilton SD. Morpholino Oligomer-Mediated Exon Skipping Averts the Onset of Dystrophic Pathology in the mdx Mouse. Mol Ther. 2007 Sep;15(9):1587-92. Epub 2007 Jun 19.. |
Morpholino phenocopies of sqt, oep, and ntl mutations
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Citation:
Genesis. 2001 Jul;30(3):175-7 Epub:
Not Epub Abstract:
No abstract available. Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Feldman B, Stemple DL. Morpholino phenocopies of sqt, oep, and ntl mutations. Genesis. 2001 Jul;30(3):175-7. |
Multiple functions of Cerberus cooperate to induce heart downstream of Nodal
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Citation:
Dev Biol. 2007 Mar 1;303(1):57-65. Epub 2006 Oct 26. Epub:
Not Epub Abstract:
The TGFbeta family member Nodal has been implicated in heart induction through misexpression of a dominant negative version of... Organism or Cell Type:
Xenopus Citation Extract: Foley AC, Korol O, Timmer AM, Mercola M. Multiple functions of Cerberus cooperate to induce heart downstream of Nodal. Dev Biol. 2007 Mar 1;303(1):57-65. Epub 2006 Oct 26.. |
Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease
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Citation:
Dis Model Mech. 2012 Mar;5(2):248-58. Epub 2011 Nov 1 Epub:
Not Epub Abstract:
Analysis of zebrafish mutants that demonstrate abnormal locomotive behavior can elucidate the molecular requirements for neural... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Friedrich T, Lambert AM, Masino MA, Downes GB. Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease. Dis Model Mech. 2012 Mar;5(2):248-58. Epub 2011 Nov 1. |
Neonatal growth and regeneration of beta cells are regulated by the Wnt/beta-catenin signaling in normal and diabetic rats
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Citation:
Am J Physiol Endocrinol Metab. 2009 Nov 17. [Epub ahead of print] Epub:
Not Epub Abstract:
Wnt/beta-catenin signaling is critical for a variety of fondamental cellular processes. Here we investigated the implication of... Delivery Method:
Endo-Porter in culture, s.c. injection in vivo Organism or Cell Type:
cell culture: INS-1 cells (clone 368) and Wistar rat pups Citation Extract: Figeac F, Uzan B, Faro M, Chelali N, Portha B, Movassat J. Neonatal growth and regeneration of beta cells are regulated by the Wnt/beta-catenin signaling in normal and diabetic rats. Am J Physiol Endocrinol Metab. 2009 Nov 17. [Epub ahead of print]. |
Neuropilin-1a is involved in trunk motor axon outgrowth in embryonic zebrafish
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Citation:
Dev Dyn. 2005 Nov;234(3):535-49. Epub:
Not Epub Abstract:
Neuropilin-1, a receptor for axon-repellent semaphorins and vascular endothelial growth factor (VEGF), functions both in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Feldner J, Becker T, Goishi K, Schweitzer J, Lee P, Schachner M, Klagsbrun M, Becker CG. Neuropilin-1a is involved in trunk motor axon outgrowth in embryonic zebrafish. Dev Dyn. 2005 Nov;234(3):535-49.. |
Nodal/activin signaling establishes oral-aboral polarity in the early sea urchin embryo
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Citation:
Dev Dyn. 2004 Dec;231(4):727-40. Epub:
Not Epub Abstract:
Components of the Wnt signaling pathway are involved in patterning the sea urchin primary or animal-vegetal (AV) axis, but the... Delivery Method:
Microinjection Organism or Cell Type:
L. variegatus Citation Extract: Flowers VL, Courteau GR, Poustka AJ, Weng W, Venuti JM. Nodal/activin signaling establishes oral-aboral polarity in the early sea urchin embryo. Dev Dyn. 2004 Dec;231(4):727-40.. |