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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin function
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Citation:
Development. 2010 Oct;137(19):3215-20. Epub 2010 Aug 19 Epub:
Not Epub Abstract:
Heart formation requires the fusion of bilateral cardiomyocyte populations as they move towards the embryonic midline. The bHLH... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Garavito-Aguilar ZV, Riley HE, Yelon D. Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin function. Development. 2010 Oct;137(19):3215-20. Epub 2010 Aug 19. |
Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly
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Citation:
Dev Cell. 2008 Aug;15(2):236-47 Epub:
Not Epub Abstract:
Holoprosencephaly (HPE), the most common forebrain malformation, is characterized by an incomplete separation of the cerebral... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Geng X, Speirs C, Lagutin O, Inbal A, Liu W, Solnica-Krezel L, Jeong Y, Epstein DJ, Oliver G. Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell. 2008 Aug;15(2):236-47. |
Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos
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Citation:
Dev Cell. 2005 Mar;8(3):389-400 Epub:
Not Epub Abstract:
Studies with embryonic explants and embryonic stem cells have suggested a role for Hedgehog (Hh) signaling in hematopoiesis.... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Gering M, Patient R. Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos. Dev Cell. 2005 Mar;8(3):389-400. |
Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary
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Citation:
Development. 2004 May;131(9):1993-2006. Epub 2004 Mar 31 Epub:
Not Epub Abstract:
Neurogenesis in both vertebrates and invertebrates is tightly controlled in time and space involving both positive and negative... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Geling A, Plessy C, Rastegar S, Strähle U, Bally-Cuif L. Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary. Development. 2004 May;131(9):1993-2006. Epub 2004 Mar 31. |
Homer regulates calcium signalling in growth cone turning
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Citation:
Neural Dev. 2009 Aug 3;4:29 Epub:
Not Epub Abstract:
BACKGROUND: Homer proteins are post-synaptic density proteins with known functions in receptor trafficking and calcium... Delivery Method:
syringe loading Organism or Cell Type:
Dorsal root ganglia (DRG) sensory neurons from Wistar rats Citation Extract: Gasperini R, Choi-Lundberg D, Thompson MJ, Mitchell CB, Foa L. Homer regulates calcium signalling in growth cone turning. Neural Dev. 2009 Aug 3;4:29. |
HpSulf, a heparan sulfate 6-O-endosulfatase, is involved in the regulation of VEGF signaling during sea urchin development
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Citation:
Mech Dev. 2009 Dec 24. [Epub ahead of print] Epub:
Not Epub Abstract:
Cell surface heparan sulfate proteoglycans (HSPGs) play significant roles in the regulation of developmental signaling,... Delivery Method:
Microinjection Organism or Cell Type:
Sea urchin, Hemicentrotus pulcherrimus Citation Extract: Fujita K, Takechi E, Sakamoto N, Sumiyoshi N, Izumi S, Miyamoto T, Matsuura S, Tsurugaya T, Akasaka K, Yamamoto T. HpSulf, a heparan sulfate 6-O-endosulfatase, is involved in the regulation of VEGF signaling during sea urchin development. Mech Dev. 2009 Dec 24. [Epub ahead of print]. |
Human retinopathy-associated ciliary protein Retinitis Pigmentosa GTPase Regulator (RPGR) regulates cilia-dependent vertebrate development
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Citation:
Hum Mol Genet. 2009 Oct 8. [Epub ahead of print] Epub:
Not Epub Abstract:
Dysfunction of primary cilia is associated with tissue-specific or syndromic disorders. RPGR is a ciliary protein, mutations in... Organism or Cell Type:
zebrafish Citation Extract: Ghosh AK, Murga-Zamalloa CA, Chan L, Hitchcock PF, Swaroop A, Khanna H. Human retinopathy-associated ciliary protein Retinitis Pigmentosa GTPase Regulator (RPGR) regulates cilia-dependent vertebrate development. Hum Mol Genet. 2009 Oct 8. [Epub ahead of print]. |
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis
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Citation:
J Clin Invest. 2010 Oct 25. pii: 42980. doi: 10.1172/JCI42980. [Epub ahead of print] Epub:
Not Epub Abstract:
Adaptive changes to oxygen availability are critical for cell survival and tissue homeostasis. Prolonged oxygen deprivation due... Delivery Method:
Endo-Porter Organism or Cell Type:
Cell Culture: human umbilical vein endothelial cells (HUVECs) Citation Extract: Ghosh G, Subramanian IV, Adhikari N, Zhang X, Joshi HP, Basi D, Chandrashekhar YS, Hall JL, Roy S, Zeng Y, Ramakrishnan S. Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis. J Clin Invest. 2010 Oct 25. pii: 42980. doi: 10.1172/JCI42980. [Epub ahead of print]. |
Identification of direct T-box target genes in the developing zebrafish mesoderm
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Citation:
Development. 2009 Mar;136(5):749-60. Epub 2009 Jan 21 Epub:
Not Epub Abstract:
The zebrafish genes spadetail (spt) and no tail (ntl) encode T-box transcription factors that are important for early mesoderm... Organism or Cell Type:
zebrafish Citation Extract: Garnett AT, Han TM, Gilchrist MJ, Smith JC, Eisen MB, Wardle FC, Amacher SL. Identification of direct T-box target genes in the developing zebrafish mesoderm. Development. 2009 Mar;136(5):749-60. Epub 2009 Jan 21. |
In Vivo T-Box Transcription Factor Profiling Reveals Joint Regulation of Embryonic Neuromesodermal Bipotency
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Citation:
Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.08.012 Epub:
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The design of effective cell replacement therapies requires detailed knowledge of how embryonic stem cells form primary tissues... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Gentsch GE, Owens NDL, Martin SR, Piccinelli P, Faial T, Trotter MWB, Gilchrist MJ, Smith JC. In Vivo T-Box Transcription Factor Profiling Reveals Joint Regulation of Embryonic Neuromesodermal Bipotency. Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.08.012. |