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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

NPHP4 Variants Are Associated With Pleiotropic Heart Malformations

Authors:
French VM, van de Laar IMBH, Wessels MW, Christan Rohe C, Roos-Hesselink JW, Wang W, Frohn-Mulder IME Severijnen L-A, de Graaf BM, Schot R, Breedveld G, Mientjes E, van Tienhoven M, Jadot E, Jiang Z, Verkerk A, Swagemakers S, Venselaar H, Rahimi Z, Najmabadi H, Meijers-Heijboer H, de Graaff E, Helbing WA, Willemsen R, Devriendt K, Belmont JW, Oostra BA, Amack JD, Bertoli-Avella AM
Citation:
Circ Res. 2012;[Epub ahead of print] doi:10.1161/CIRCRESAHA.112.269795
Epub:
Not Epub
Abstract:
Rationale: Congenital heart malformations are a major cause of morbidity and mortality, especially in young children. Failure...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
French VM, van de Laar IMBH, Wessels MW, Christan Rohe C, Roos-Hesselink JW, Wang W, Frohn-Mulder IME Severijnen L-A, de Graaf BM, Schot R, Breedveld G, Mientjes E, van Tienhoven M, Jadot E, Jiang Z, Verkerk A, Swagemakers S, Venselaar H, Rahimi Z, Najmabadi H, Meijers-Heijboer H, de Graaff E, Helbing WA, Willemsen R, Devriendt K, Belmont JW, Oostra BA, Amack JD, Bertoli-Avella AM. NPHP4 Variants Are Associated With Pleiotropic Heart Malformations. Circ Res. 2012;[Epub ahead of print] doi:10.1161/CIRCRESAHA.112.269795.

p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death

Authors:
Feng X, Liu X, Zhang W, Xiao W
Citation:
EMBO J. 2011 Jul 26;30(16):3397-415. doi: 10.1038/emboj.2011.248
Epub:
Not Epub
Abstract:
Hypoxia stabilizes the tumour suppressor p53, allowing it to function primarily as a transrepressor; however, the function of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feng X, Liu X, Zhang W, Xiao W. p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death. EMBO J. 2011 Jul 26;30(16):3397-415. doi: 10.1038/emboj.2011.248.

Pbx homeodomain proteins pattern both the zebrafish retina and tectum

Authors:
French CR, Erickson T, Callander D, Berry KM, Koss R, Hagey DW, Stout J, Wuennenberg-Stapleton K, Ngai J, Moens CB, Waskiewicz AJ
Citation:
BMC Dev Biol. 2007 Jul 16;7:85
Epub:
Not Epub
Abstract:
BACKGROUND: Pbx genes encode TALE class homeodomain transcription factors that pattern the developing neural tube, pancreas,...
Organism or Cell Type:
zebrafish
Citation Extract:
French CR, Erickson T, Callander D, Berry KM, Koss R, Hagey DW, Stout J, Wuennenberg-Stapleton K, Ngai J, Moens CB, Waskiewicz AJ. Pbx homeodomain proteins pattern both the zebrafish retina and tectum. BMC Dev Biol. 2007 Jul 16;7:85.

Pivotal role of hmx2 and hmx3 in zebrafish inner ear and lateral line development

Authors:
Feng Y, Xu Q
Citation:
Dev Biol. 2009 Dec 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
hmx2 (nkx5.2) and hmx3 (nkx5.1) are highly conserved homeobox transcription factors required for mouse inner ear development....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feng Y, Xu Q. Pivotal role of hmx2 and hmx3 in zebrafish inner ear and lateral line development. Dev Biol. 2009 Dec 28. [Epub ahead of print].

PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish

Authors:
Feldner J, Reimer MM, Schweitzer J, Wendik B, Meyer D, Becker T, Becker CG
Citation:
J Neurosci. 2007 May 2;27(18):4978-83
Epub:
Not Epub
Abstract:
The pioneering primary motor axons in the zebrafish trunk are guided by multiple cues along their pathways. Plexins are...
Organism or Cell Type:
zebrafish
Citation Extract:
Feldner J, Reimer MM, Schweitzer J, Wendik B, Meyer D, Becker T, Becker CG. PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish. J Neurosci. 2007 May 2;27(18):4978-83.

Regulator of g protein signaling 3 modulates wnt5b calcium dynamics and somite patterning

Authors:
Freisinger CM, Fisher RA, Slusarski DC
Citation:
PLoS Genet. 2010 Jul 8;6(7):e1001020
Epub:
Not Epub
Abstract:
Vertebrate development requires communication among cells of the embryo in order to define the body axis, and the Wnt-signaling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Freisinger CM, Fisher RA, Slusarski DC. Regulator of g protein signaling 3 modulates wnt5b calcium dynamics and somite patterning. PLoS Genet. 2010 Jul 8;6(7):e1001020.

Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects

Authors:
Franzosa JA, Bugel SM, Tal TL, La Du JK, Tilton SC, Waters KM, Tanguay RL
Citation:
FASEB J. 2013 Dec;27(12):4866-76. doi: 10.1096/fj.12-225524. Epub 2013 Aug 23
Epub:
Not Epub
Abstract:
Retinoic acid (RA) is involved in multifarious and complex functions necessary for vertebrate development. RA signaling is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Franzosa JA, Bugel SM, Tal TL, La Du JK, Tilton SC, Waters KM, Tanguay RL. Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB J. 2013 Dec;27(12):4866-76. doi: 10.1096/fj.12-225524. Epub 2013 Aug 23.

scn1bb, a Zebrafish Ortholog of SCN1B Expressed in Excitable and Nonexcitable Cells, Affects Motor Neuron Axon Morphology and Touch Sensitivity

Authors:
Fein AJ, Wright MA, Slat EA, Ribera AB, Isom LL
Citation:
J Neurosci. 2008 Nov 19;28(47):12510-12522
Epub:
Not Epub
Abstract:
Voltage-gated Na(+) channels initiate and propagate action potentials in excitable cells. Mammalian Na(+) channels are composed...
Organism or Cell Type:
zebrafish
Citation Extract:
Fein AJ, Wright MA, Slat EA, Ribera AB, Isom LL. scn1bb, a Zebrafish Ortholog of SCN1B Expressed in Excitable and Nonexcitable Cells, Affects Motor Neuron Axon Morphology and Touch Sensitivity. J Neurosci. 2008 Nov 19;28(47):12510-12522.

Site-specific DICER and DROSHA RNA products control the DNA-damage response

Authors:
Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, Mione M, Carninci P, d’Adda di Fagagna F
Citation:
Nature. 2012;[epub ahead of print] doi:10.1038/nature11179
Epub:
Not Epub
Abstract:
Non-coding RNAs (ncRNAs) are involved in an increasingly recognized number of cellular events. Some ncRNAs are processed by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, Mione M, Carninci P, d’Adda di Fagagna F. Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature. 2012;[epub ahead of print] doi:10.1038/nature11179.

Subfunctionalization of a retinoid-binding protein provides evidence for two parallel visual cycles in the cone-dominant zebrafish retina

Authors:
Fleisch VC, Schonthaler HB, von Lintig J, Neuhauss SC
Citation:
J Neurosci. 2008 Aug 13;28(33):8208-16
Epub:
Not Epub
Abstract:
In vertebrates, the absorption of a photon results in an 11-cis to all-trans isomerization of the retinylidene chromophore of...
Organism or Cell Type:
zebrafish
Citation Extract:
Fleisch VC, Schonthaler HB, von Lintig J, Neuhauss SC. Subfunctionalization of a retinoid-binding protein provides evidence for two parallel visual cycles in the cone-dominant zebrafish retina. J Neurosci. 2008 Aug 13;28(33):8208-16.

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