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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
A mild neurofibromatosis type 1 phenotype produced by the combination of the benign nature of a leaky NF1-splice mutation and the presence of a complex mosaicism
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Citation:
Hum Mutat. 2011 Mar 10. doi: 10.1002/humu.21500. [Epub ahead of print] Epub:
Not Epub Abstract:
Here we analyze the genetic and molecular basis responsible for a very benign phenotype observed in a NF1 patient.... Citation Extract: Fernández-Rodríguez J, Castellsagué J, Benito L, Benavente Y, Capellà G, Blanco I, Serra E, Lázaro C. A mild neurofibromatosis type 1 phenotype produced by the combination of the benign nature of a leaky NF1-splice mutation and the presence of a complex mosaicism. Hum Mutat. 2011 Mar 10. doi: 10.1002/humu.21500. [Epub ahead of print]. |
A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition
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Citation:
PLoS ONE. 2008;3(12):e4109. Epub 2008 Dec 31 Epub:
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BACKGROUND: Compared to the emerging embryonic stem cell (ESC) gene network, little is known about the dynamic gene network... Delivery Method:
Microinjection Organism or Cell Type:
Mouse embryo Citation Extract: Foygel K, Choi B, Jun S, Leong DE, Lee A, Wong CC, Zuo E, Eckart M, Reijo Pera RA, Wong WH, Yao MW. A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition. PLoS ONE. 2008;3(12):e4109. Epub 2008 Dec 31. |
A role for GATA factors in Xenopus gastrulation movements
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Citation:
Mech Dev. 2006 Oct;123(10):730-45. Epub 2006 Jul 26. Epub:
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Gastrulation movements in Xenopus laevis are becoming increasingly well characterised, however the molecular mechanisms... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Fletcher G, Jones GE, Patient R, Snape A. A role for GATA factors in Xenopus gastrulation movements. Mech Dev. 2006 Oct;123(10):730-45. Epub 2006 Jul 26.. |
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish
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Citation:
Development. 2011 Apr;138(7):1409-19 Epub:
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Members of the Slit family of secreted ligands interact with Roundabout (Robo) receptors to provide guidance cues for many cell... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development. 2011 Apr;138(7):1409-19. |
A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway
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Citation:
Development. 2012 Jul;139(13):2416-25. doi: 10.1242/dev.063206 Epub:
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Multiple developmental processes require tightly controlled Wnt signaling, and its misregulation leads to congenital... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Flowers GP, Topczewska JM, Topczewski J. A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway. Development. 2012 Jul;139(13):2416-25. doi: 10.1242/dev.063206. |
Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos
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Citation:
BMC Biol. 2013 Jun 17;11(1):69. [Epub ahead of print] Epub:
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BACKGROUND: In mammals, ABCB1 constitutes a cellular \"first line of defense\" against a wide array of chemicals and... Organism or Cell Type:
zebrafish Citation Extract: Fischer S, Klüver N, Burkhardt-Medicke K, Pietsch M, Schmidt AM, Wellner P, Schirmer K, Luckenbach T. Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos. BMC Biol. 2013 Jun 17;11(1):69. [Epub ahead of print]. |
Altered Chondrocyte Differentiation and Extracellular Matrix Homeostasis in a Zebrafish Model for Mucolipidosis II
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Citation:
Am J Pathol. 2009 Oct 15. [Epub ahead of print] Epub:
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Mucolipidosis II (ML-II) is a pediatric disorder caused by defects in the biosynthesis of mannose 6-phosphate, the carbohydrate... Organism or Cell Type:
zebrafish Citation Extract: Flanagan-Steet H, Sias C, Steet R. Altered Chondrocyte Differentiation and Extracellular Matrix Homeostasis in a Zebrafish Model for Mucolipidosis II. Am J Pathol. 2009 Oct 15. [Epub ahead of print]. |
An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases
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Citation:
BMC Mol Biol. 2012;13:6 doi:10.1186/1471-2199-13-6 Epub:
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RNA interference (RNAi) and antisense strategies provide experimental therapeutic agents for numerous diseases, including... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary human fibroblasts, Huntington disease Citation Extract: Fiszer A, Olejniczak M, Switonski PM, Wroblewska JP, Wisniewska-Kruk JW, Mykowska A, Krzyzosiak WJ. An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases. BMC Mol Biol. 2012;13:6 doi:10.1186/1471-2199-13-6. |
Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish
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Citation:
Neurogastroenterol Motil. 2009 Mar;21(3):304-12. Epub 2008 Dec 31 Epub:
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Gastrointestinal function depends upon coordinated contractions to mix and propel food through the gut. Deregulation of these... Organism or Cell Type:
zebrafish Citation Extract: Field HA, Kelley KA, Martell L, Goldstein AM, Serluca FC. Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish. Neurogastroenterol Motil. 2009 Mar;21(3):304-12. Epub 2008 Dec 31. |
Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development
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Citation:
Dev Biol. 2012 Jun 20. [Epub ahead of print] Epub:
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Distinct groups of dopaminergic neurons develop at defined anatomical sites in the brain to modulate function of a large... Organism or Cell Type:
zebrafish Citation Extract: Filippi A, Jainok C, Driever W. Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development. Dev Biol. 2012 Jun 20. [Epub ahead of print]. |