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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

Authors:
Hinkes B, Wiggins RC, Gbadegesin R, Vlangos CN, Seelow D, Nurnberg G, Garg P, Verma R, Chaib H, Hoskins BE, Ashraf S, Becker C, Hennies HC, Goyal M, Wharram BL, Schachter AD, Mudumana S, Drummond I, Kerjaschki D, Waldherr R, Dietrich A, Ozaltin F, Bakkaloglu A, Cleper R, Basel-Vanagaite L, Pohl M, Griebel M, Tsygin AN, Soylu A, Muller D, Sorli CS, Bunney TD, Katan M, Liu J, Attanasio M, O'toole JF, Hasselbacher K, Mucha B, Otto EA, Airik R, Kispert A, Kelley GG, Smrcka AV, Gudermann T, Holzman LB, Nurnberg P, Hildebrandt F
Citation:
Nat Genet. 2006 Dec;38(12):1397-405. Epub 2006 Nov 5.
Epub:
Not Epub
Abstract:
Nephrotic syndrome, a malfunction of the kidney glomerular filter, leads to proteinuria, edema and, in steroid-resistant...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hinkes B, Wiggins RC, Gbadegesin R, Vlangos CN, Seelow D, Nurnberg G, Garg P, Verma R, Chaib H, Hoskins BE, Ashraf S, Becker C, Hennies HC, Goyal M, Wharram BL, Schachter AD, Mudumana S, Drummond I, Kerjaschki D, Waldherr R, Dietrich A, Ozaltin F, Bakkaloglu A, Cleper R, Basel-Vanagaite L, Pohl M, Griebel M, Tsygin AN, Soylu A, Muller D, Sorli CS, Bunney TD, Katan M, Liu J, Attanasio M, O'toole JF, Hasselbacher K, Mucha B, Otto EA, Airik R, Kispert A, Kelley GG, Smrcka AV, Gudermann T, Holzman LB, Nurnberg P, Hildebrandt F. Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.. Nat Genet. 2006 Dec;38(12):1397-405. Epub 2006 Nov 5..

Pregnenolone stabilizes microtubules and promotes zebrafish embryonic cell movement

Authors:
Hsu HJ, Liang MR, Chen CT, Chung BC
Citation:
Nature. 2006 Jan 26;439(7075):480-3
Epub:
Not Epub
Abstract:
Embryonic cell movement is essential for morphogenesis and the establishment of body shapes, but little is known about its...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsu HJ, Liang MR, Chen CT, Chung BC. Pregnenolone stabilizes microtubules and promotes zebrafish embryonic cell movement. Nature. 2006 Jan 26;439(7075):480-3.

PSF controls expression of histone variants and cellular viability in thymocytes

Authors:
Heyd F, Lynch KW
Citation:
Biochem Biophys Res Commun. 2011 Nov 4;414(4):743-9. doi: 10.1016/j.bbrc.2011.09.149. Epub 2011 Oct 6
Epub:
Not Epub
Abstract:
Even with the availability of tissue-restricted knockouts, studying the role of essential, multifunctional proteins in vivo is...
Organism or Cell Type:
cell culture: human JSL1 T-cell line
Citation Extract:
Heyd F, Lynch KW. PSF controls expression of histone variants and cellular viability in thymocytes. Biochem Biophys Res Commun. 2011 Nov 4;414(4):743-9. doi: 10.1016/j.bbrc.2011.09.149. Epub 2011 Oct 6.

PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function

Authors:
Hill MM, Bastiani M, Luetterforst R, Kirkham M, Kirkham A, Nixon SJ, Walser P, Abankwa D, Oorschot VM, Martin S, Hancock JF, Parton RG
Citation:
Cell. 2008 Jan 11;132(1):113-24
Epub:
Not Epub
Abstract:
Caveolae are abundant cell-surface organelles involved in lipid regulation and endocytosis. We used comparative proteomics to...
Organism or Cell Type:
zebrafish
Citation Extract:
Hill MM, Bastiani M, Luetterforst R, Kirkham M, Kirkham A, Nixon SJ, Walser P, Abankwa D, Oorschot VM, Martin S, Hancock JF, Parton RG. PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell. 2008 Jan 11;132(1):113-24.

Quantitative assay for TALEN activity at endogenous genomic loci

Authors:
Hisano Y, Ota S, Arakawa K, Muraki M, Kono N, Oshita K, Sakuma T, Tomita M, Yamamoto T, Okada Y, Kawahara A
Citation:
Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133871
Epub:
Not Epub
Abstract:
Artificially designed nucleases such as zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (...
Organism or Cell Type:
zebrafish
Citation Extract:
Hisano Y, Ota S, Arakawa K, Muraki M, Kono N, Oshita K, Sakuma T, Tomita M, Yamamoto T, Okada Y, Kawahara A. Quantitative assay for TALEN activity at endogenous genomic loci. Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133871 .

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

Authors:
Hofmann TG, Moller A, Sirma H, Zentgraf H, Taya Y, Droge W, Will H, Schmitz ML
Citation:
Nat Cell Biol. 2002 Jan;4(1):1-10
Epub:
Not Epub
Abstract:
Transcriptional activity of p53, a central regulatory switch in a network controlling cell proliferation and apoptosis, is...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: U2OS cells
Citation Extract:
Hofmann TG, Moller A, Sirma H, Zentgraf H, Taya Y, Droge W, Will H, Schmitz ML. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol. 2002 Jan;4(1):1-10.

Regulation of TCF3 by Wnt-Dependent Phosphorylation during Vertebrate Axis Specification

Authors:
Hikasa H, Ezan J, Itoh K, Li X, Klymkowsky MW, Sokol SY
Citation:
Dev Cell. 2010 Oct 19;19(4):521-32
Epub:
Not Epub
Abstract:
A commonly accepted model of Wnt/β-catenin signaling involves target gene activation by a complex of β-catenin with a T-cell...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Hikasa H, Ezan J, Itoh K, Li X, Klymkowsky MW, Sokol SY. Regulation of TCF3 by Wnt-Dependent Phosphorylation during Vertebrate Axis Specification. Dev Cell. 2010 Oct 19;19(4):521-32.

Regulation of TGF-{beta} signalling by N-acetylgalactosaminyltransferase-like 1

Authors:
Herr P, Korniychuk G, Yamamoto Y, Grubisic K, Oelgeschläger M
Citation:
Development. 2008 May;135(10):1813-22. Epub 2008 Apr 16.
Epub:
Not Epub
Abstract:
The TGF-beta superfamily of secreted signalling molecules plays a pivotal role in the regulation of early embryogenesis,...
Organism or Cell Type:
Xenopus
Citation Extract:
Herr P, Korniychuk G, Yamamoto Y, Grubisic K, Oelgeschläger M. Regulation of TGF-{beta} signalling by N-acetylgalactosaminyltransferase-like 1. Development. 2008 May;135(10):1813-22. Epub 2008 Apr 16..

Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish

Authors:
Holzschuh J, Wada N, Wada C, Schaffer A, Javidan Y, Tallafuss A, Bally-Cuif L, Schilling TF
Citation:
Development. 2005 Aug;132(16):3731-42
Epub:
Not Epub
Abstract:
Cranial sensory neurons largely derive from neurogenic placodes (epibranchial and dorsolateral), which are ectodermal...
Organism or Cell Type:
zebrafish
Citation Extract:
Holzschuh J, Wada N, Wada C, Schaffer A, Javidan Y, Tallafuss A, Bally-Cuif L, Schilling TF. Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish. Development. 2005 Aug;132(16):3731-42.

Restaging the spindle assembly checkpoint in female mammalian meiosis I

Authors:
Homer HA, McDougall A, Levasseur M, Herbert M
Citation:
Cell Cycle. 2005 May;4(5):650-3. Epub 2005 May 14.
Epub:
Not Epub
Abstract:
In mammalian somatic cells, the spindle assembly checkpoint (SAC) is indispensable for ensuring the fidelity of chromosome...
Delivery Method:
not applicable
Organism or Cell Type:
mouse oocytes
Citation Extract:
Homer HA, McDougall A, Levasseur M, Herbert M. Restaging the spindle assembly checkpoint in female mammalian meiosis I. Cell Cycle. 2005 May;4(5):650-3. Epub 2005 May 14..

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