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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Asymmetric PI(3,4,5)P3 and Akt signaling mediates chemotaxis of axonal growth cones

Authors:
Henle SJ, Wang G, Liang E, Wu M, Poo MM, Henley JR
Citation:
J Neurosci. 2011 May 11;31(19):7016-27
Epub:
Not Epub
Abstract:
The action of many extracellular guidance cues on axon pathfinding requires Ca2+ influx at the growth cone (Hong et al., 2000;...
Delivery Method:
Microinjection
Organism or Cell Type:
cell culture: Xenopus laevis spinal neurons
Citation Extract:
Henle SJ, Wang G, Liang E, Wu M, Poo MM, Henley JR. Asymmetric PI(3,4,5)P3 and Akt signaling mediates chemotaxis of axonal growth cones. J Neurosci. 2011 May 11;31(19):7016-27.

Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization

Authors:
Hernandez-Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D, Knight M, Beales PL
Citation:
Hum Mol Genet. 2013 Oct 1;22(19):3858-68. doi: 10.1093/hmg/ddt241. Epub 2013 May 27
Epub:
Not Epub
Abstract:
Primary cilia are cellular appendages important for signal transduction and sensing the environment. Bardet–Biedl syndrome...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hernandez-Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D, Knight M, Beales PL. Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization. Hum Mol Genet. 2013 Oct 1;22(19):3858-68. doi: 10.1093/hmg/ddt241. Epub 2013 May 27.

beta-Catenin is required for the establishment of vegetal embryonic fates in the nemertean, Cerebratulus lacteus

Authors:
Henry JQ, Perry KJ, Wever J, Seaver E, Martindale MQ
Citation:
Dev Biol. 2008 May 1;317(1):368-79. Epub 2008 Mar 5.
Epub:
Not Epub
Abstract:
Downstream components of the canonical Wnt signaling pathway that result in the nuclear localization of beta-catenin are...
Organism or Cell Type:
Cerebratulus lacteus
Citation Extract:
Henry JQ, Perry KJ, Wever J, Seaver E, Martindale MQ. beta-Catenin is required for the establishment of vegetal embryonic fates in the nemertean, Cerebratulus lacteus. Dev Biol. 2008 May 1;317(1):368-79. Epub 2008 Mar 5..

Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach

Authors:
Heasman J, Kofron M, and Wylie C
Citation:
Developmental Biology 2000 222: 124-134
Epub:
Not Epub
Abstract:
Xenopus embryos develop dorsal/ventral and anterior/posterior axes as a result of the activity of a maternal Xwnt pathway, in...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Heasman J, Kofron M, and Wylie C. Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach. Developmental Biology 2000 222: 124-134.

Changes in retinoic acid signaling alter otic patterning

Authors:
Hans S, Westerfield M
Citation:
Development. 2007 Jul;134(13):2449-58. Epub 2007 May 23.
Epub:
Not Epub
Abstract:
Retinoic acid (RA) has pleiotropic functions during embryogenesis. In zebrafish, increasing or blocking RA signaling results in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hans S, Westerfield M. Changes in retinoic acid signaling alter otic patterning. Development. 2007 Jul;134(13):2449-58. Epub 2007 May 23..

Characterization of the heme synthesis enzyme coproporphyrinogen oxidase (CPO) in zebrafish erythrogenesis

Authors:
Hanaoka R, Katayama S, Dawid IB, Kawahara A
Citation:
Genes Cells. 2006 Mar;11(3):293-303
Epub:
Not Epub
Abstract:
Hemoglobin consists of heme and globin proteins and is essential for oxygen transport in all vertebrates. Although biochemical...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hanaoka R, Katayama S, Dawid IB, Kawahara A. Characterization of the heme synthesis enzyme coproporphyrinogen oxidase (CPO) in zebrafish erythrogenesis. Genes Cells. 2006 Mar;11(3):293-303.

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

Authors:
Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Özen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F
Citation:
J. Clin. Invest. 2011;[Epub ahead of print] doi:10.1172/JCI45693
Epub:
Not Epub
Abstract:
Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of end-stage renal failure. Identification of single-gene...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Özen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F. COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J. Clin. Invest. 2011;[Epub ahead of print] doi:10.1172/JCI45693.

Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation

Authors:
Haunhorst P, Hanschmann EM, Bräutigam L, Stehling O, Hoffmann B, Mühlenhoff U, Lill R, Berndt C, Lillig CH
Citation:
Mol Biol Cell. 2013 Jun;24(12):1895-903. doi: 10.1091/mbc.E12-09-0648. Epub 2013 Apr 24
Epub:
Not Epub
Abstract:
The mechanisms by which eukaryotic cells handle and distribute the essential micronutrient iron within the cytosol and other...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Haunhorst P, Hanschmann EM, Bräutigam L, Stehling O, Hoffmann B, Mühlenhoff U, Lill R, Berndt C, Lillig CH. Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation. Mol Biol Cell. 2013 Jun;24(12):1895-903. doi: 10.1091/mbc.E12-09-0648. Epub 2013 Apr 24.

Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development

Authors:
Hernandez RE, Putzke AP, Myers JP, Margaretha L, Moens CB
Citation:
Development. 2007 Jan;134(1):177-87
Epub:
Not Epub
Abstract:
Retinoic acid (RA) is essential for normal vertebrate development, including the patterning of the central nervous system....
Organism or Cell Type:
zebrafish
Citation Extract:
Hernandez RE, Putzke AP, Myers JP, Margaretha L, Moens CB. Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development. 2007 Jan;134(1):177-87.

Deficient Zebrafish Ether-a-Go-Go-Related Gene Channel Gating Causes Short-QT Syndrome in Zebrafish Reggae Mutants.

Authors:
Hassel D, Scholz EP, Trano N, Friedrich O, Just S, Meder B, Weiss DL, Zitron E, Marquart S, Vogel B, Karle CA, Seemann G, Fishman MC, Katus HA, Rottbauer W
Citation:
Circulation, 2008 Feb 19;117(7):866-75. Epub 2008 Feb 4.
Epub:
Not Epub
Abstract:
BACKGROUND: -Genetic predisposition is believed to be responsible for most clinically significant arrhythmias; however,...
Organism or Cell Type:
zebrafish
Citation Extract:
Hassel D, Scholz EP, Trano N, Friedrich O, Just S, Meder B, Weiss DL, Zitron E, Marquart S, Vogel B, Karle CA, Seemann G, Fishman MC, Katus HA, Rottbauer W. Deficient Zebrafish Ether-a-Go-Go-Related Gene Channel Gating Causes Short-QT Syndrome in Zebrafish Reggae Mutants. . Circulation, 2008 Feb 19;117(7):866-75. Epub 2008 Feb 4..

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