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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure

Authors:
Holden KL, Stein DA, Pierson TC, Ahmed AA, Clyde K, Iversen PL, Harris E
Citation:
Virology. 2006 Jan 20;344(2):439-52. Epub 2005 Oct 7.
Epub:
Not Epub
Abstract:
Dengue virus (DEN) is a major public health problem worldwide and causes a spectrum of diseases, for which no antiviral...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: BHK cells
Citation Extract:
Holden KL, Stein DA, Pierson TC, Ahmed AA, Clyde K, Iversen PL, Harris E. Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. Virology. 2006 Jan 20;344(2):439-52. Epub 2005 Oct 7..

Inhibition of germ cell proliferation by the medaka male determining gene Dmrt1bY

Authors:
Herpin A, Schindler D, Kraiss A, Hornung U, Winkler C, Schartl M
Citation:
BMC Dev Biol. 2007 Aug 30;7(1):99 [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Dmrt1 is a highly conserved gene involved in the determination and early differentiation phase of the...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Herpin A, Schindler D, Kraiss A, Hornung U, Winkler C, Schartl M. Inhibition of germ cell proliferation by the medaka male determining gene Dmrt1bY. BMC Dev Biol. 2007 Aug 30;7(1):99 [Epub ahead of print].

Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia

Authors:
Hoffmann S, Berger IM, Glaser A, Bacon C, Li L, Gretz N, Steinbeisser H, Rottbauer W, Just S, Rappold G
Citation:
Basic Res Cardiol. 2013 Mar;108(2):339. doi: 10.1007/s00395-013-0339-z. Epub 2013 Mar 1
Epub:
Not Epub
Abstract:
The heart’s rhythm is initiated and regulated by a group of specialized cells in the sinoatrial node (SAN), the primary...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoffmann S, Berger IM, Glaser A, Bacon C, Li L, Gretz N, Steinbeisser H, Rottbauer W, Just S, Rappold G. Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia. Basic Res Cardiol. 2013 Mar;108(2):339. doi: 10.1007/s00395-013-0339-z. Epub 2013 Mar 1.

Knockdown of V-ATPase subunit A (alphatp6v1alpha) impairs acid secretion and ion balance in zebrafish Danio rerio

Authors:
Horng JL, Lin LY, Huang CJ, Katoh F, Kaneko T, Hwang PP
Citation:
Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R2068-76. Epub 2007 Feb 1.
Epub:
Not Epub
Abstract:
In the skin of zebrafish embryo, the vacuolar H(+)-ATPase (V-ATPase, H(+) pump) distributed mainly in the apical membrane of H...
Organism or Cell Type:
zebrafish
Citation Extract:
Horng JL, Lin LY, Huang CJ, Katoh F, Kaneko T, Hwang PP. Knockdown of V-ATPase subunit A (alphatp6v1alpha) impairs acid secretion and ion balance in zebrafish Danio rerio. Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R2068-76. Epub 2007 Feb 1..

Left-sided embryonic expression of the BCL-6 corepressor, BCOR, is required for vertebrate laterality determination

Authors:
Hilton EN, Manson FD, Urquhart JE, Johnston JJ, Slavotinek AM, Hedera P, Stattin EL, Nordgren A, Biesecker LG, Black GC
Citation:
Hum Mol Genet. 2007 Jul 15;16(14):1773-82. Epub 2007 May 21.
Epub:
Not Epub
Abstract:
Oculofaciocardiodental (OFCD) syndrome is an X-linked male lethal condition encompassing cardiac septal defects, as well as...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Hilton EN, Manson FD, Urquhart JE, Johnston JJ, Slavotinek AM, Hedera P, Stattin EL, Nordgren A, Biesecker LG, Black GC. Left-sided embryonic expression of the BCL-6 corepressor, BCOR, is required for vertebrate laterality determination. Hum Mol Genet. 2007 Jul 15;16(14):1773-82. Epub 2007 May 21..

Loss of ribosomal RNA modification causes developmental defects in zebrafish

Authors:
Higa-Nakamine S, Suzuki T, Uechi T, Chakraborty A, Nakajima Y, Nakamura M, Hirano N, Suzuki T, Naoya Kenmochi N
Citation:
Nucl. Acids Res. 2012 Jan;40(1):391-8. doi: 10.1093/nar/gkr700. Epub 2011 Sep 8
Epub:
Not Epub
Abstract:
Non-coding RNAs (ncRNAs) play key roles in diverse cellular activities, and efficient ncRNA function requires extensive...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Higa-Nakamine S, Suzuki T, Uechi T, Chakraborty A, Nakajima Y, Nakamura M, Hirano N, Suzuki T, Naoya Kenmochi N. Loss of ribosomal RNA modification causes developmental defects in zebrafish. Nucl. Acids Res. 2012 Jan;40(1):391-8. doi: 10.1093/nar/gkr700. Epub 2011 Sep 8.

Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes

Authors:
Homer HA, McDougall A, Levasseur M, Murdoch AP, Herbert M
Citation:
Reproduction. 2005 Dec;130(6):829-43
Epub:
Not Epub
Abstract:
Mad2 is a pivotal component of the spindle assembly checkpoint (SAC) which inhibits anaphase promoting complex/cyclo-some (APC/...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Homer HA, McDougall A, Levasseur M, Murdoch AP, Herbert M. Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes. Reproduction. 2005 Dec;130(6):829-43.

Mad2 prevents aneuploidy and premature proteolysis of cyclin B and securin during meiosis I in mouse oocytes

Authors:
Homer HA, McDougall A, Levasseur M, Yallop K, Murdoch AP, Herbert M
Citation:
Genes Dev. 2005 Jan 15;19(2):202-7
Epub:
Not Epub
Abstract:
In mitosis, the spindle checkpoint protein Mad2 averts aneuploidy by delaying anaphase onset until chromosomes align. Here we...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Homer HA, McDougall A, Levasseur M, Yallop K, Murdoch AP, Herbert M. Mad2 prevents aneuploidy and premature proteolysis of cyclin B and securin during meiosis I in mouse oocytes. Genes Dev. 2005 Jan 15;19(2):202-7.

Manipulation of Gene Expression During Zebrafish Embryonic Development Using Transient Approaches

Authors:
Hogan BM, Verkade H, Lieschke GJ, Heath JK
Citation:
Methods Mol Biol. 2009;469:273-300
Epub:
Not Epub
Abstract:
The rapid embryonic development and high fecundity of zebrafish contribute to the great advantages of this model for the study...
Organism or Cell Type:
zebrafish
Citation Extract:
Hogan BM, Verkade H, Lieschke GJ, Heath JK. Manipulation of Gene Expression During Zebrafish Embryonic Development Using Transient Approaches. Methods Mol Biol. 2009;469:273-300.

Manipulation of hedgehog signaling in Xenopus by means of embryo microinjection and application of chemical inhibitors

Authors:
Hollemann T, Tadjuidje E, Koebernick K, Pieler T
Citation:
Methods Mol Biol. 2007;397:35-46
Epub:
Not Epub
Abstract:
Xenopus embryos provide a powerful model system to investigate the complex molecular mechanisms, which are controlled by or...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Hollemann T, Tadjuidje E, Koebernick K, Pieler T. Manipulation of hedgehog signaling in Xenopus by means of embryo microinjection and application of chemical inhibitors. Methods Mol Biol. 2007;397:35-46.

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