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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Neuropilins are positive regulators of Hedgehog signal transduction

Authors:
Hillman RT, Feng BY, Ni J, Woo WM, Milenkovic L, Hayden Gephart MG, Teruel MN, Oro AE, Chen JK, Scott MP
Citation:
Genes Dev. 2011 Nov 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Hedgehog (Hh) pathway is essential for vertebrate embryogenesis, and excessive Hh target gene activation can cause cancer...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hillman RT, Feng BY, Ni J, Woo WM, Milenkovic L, Hayden Gephart MG, Teruel MN, Oro AE, Chen JK, Scott MP. Neuropilins are positive regulators of Hedgehog signal transduction. Genes Dev. 2011 Nov 3. [Epub ahead of print].

New approaches to treatment of primary immunodeficiencies: fixing mutations with chemicals

Authors:
Hu H, Gatti RA
Citation:
Curr Opin Allergy Clin Immunol. 2008 Dec;8(6):540-6
Epub:
Not Epub
Abstract:
PURPOSE OF REVIEW: This review is to highlight the most current mutation-targeted therapeutic approaches and provide insights...
Citation Extract:
Hu H, Gatti RA. New approaches to treatment of primary immunodeficiencies: fixing mutations with chemicals. Curr Opin Allergy Clin Immunol. 2008 Dec;8(6):540-6.

nlz Gene family is required for hindbrain patterning in the zebrafish

Authors:
Hoyle J, Tang YP, Wiellette EL, Wardle FC, Sive H
Citation:
Dev Dyn. 2004 Apr;229(4):835-46
Epub:
Not Epub
Abstract:
This study describes the conserved nlz gene family whose members encode unusual zinc finger proteins. In the zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoyle J, Tang YP, Wiellette EL, Wardle FC, Sive H. nlz Gene family is required for hindbrain patterning in the zebrafish. Dev Dyn. 2004 Apr;229(4):835-46.

Novel intronic microRNA represses zebrafish myf5 promoter activity through silencing dickkopf-3 gene

Authors:
Hsu RJ, Lin CY, Hoi HS, Zheng SK, Lin CC, Tsai HJ
Citation:
Nucleic Acids Res. 2010 Mar 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
A strong, negative cis-element located at the first intron +502/+835 (I300) of zebrafish myf5 has been reported. To elucidate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsu RJ, Lin CY, Hoi HS, Zheng SK, Lin CC, Tsai HJ. Novel intronic microRNA represses zebrafish myf5 promoter activity through silencing dickkopf-3 gene. Nucleic Acids Res. 2010 Mar 17. [Epub ahead of print].

On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis

Authors:
Holmborn K, Habicher J, Kasza Z, Eriksson AS, Filipek-Gorniok B, Gopal S, Couchman JR, Ahlberg P, Wiweger M, Spillman D, Kreuger J, Ledin J
Citation:
J. Biol. Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M112.401646
Epub:
Not Epub
Abstract:
The present study addresses the roles of heparan sulfate (HS) proteoglycans and chondroitin sulfate (CS) proteoglycans in the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Holmborn K, Habicher J, Kasza Z, Eriksson AS, Filipek-Gorniok B, Gopal S, Couchman JR, Ahlberg P, Wiweger M, Spillman D, Kreuger J, Ledin J. On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. J. Biol. Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M112.401646.

Overexpression or knockdown of rat tryptophan hyroxylase-2 has opposing effects on anxiety behavior in an estrogen-dependent manner

Authors:
Hiroi R, McDevitt RA, Morcos PA, Clark MS, Neumaier JF
Citation:
Neuroscience. 2011 Mar 10;176:120-31. Epub 2010 Dec 20.
Epub:
Not Epub
Abstract:
Previous studies showed that chronic estrogen treatment increases tryptophan hydroxylase-2 (TpH2) mRNA in the caudal dorsal...
Delivery Method:
caudal DRN infusion
Organism or Cell Type:
Rat
Citation Extract:
Hiroi R, McDevitt RA, Morcos PA, Clark MS, Neumaier JF. Overexpression or knockdown of rat tryptophan hyroxylase-2 has opposing effects on anxiety behavior in an estrogen-dependent manner. Neuroscience. 2011 Mar 10;176:120-31. Epub 2010 Dec 20..

Parallel early development of zebrafish interrenal glands and pronephros: differential control by wt1 and ff1b

Authors:
Hsu HJ, Lin G, Chung BC
Citation:
Development 2003 May;130(10):2107-16
Epub:
Not Epub
Abstract:
Steroids are synthesized mainly from the adrenal cortex. Adrenal deficiencies are often associated with problems related to its...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsu HJ, Lin G, Chung BC. Parallel early development of zebrafish interrenal glands and pronephros: differential control by wt1 and ff1b. Development 2003 May;130(10):2107-16.

Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish

Authors:
Hong JR, Lin GH, Lin CJ, Wang WP, Lee CC, Lin TL, Wu JL
Citation:
Development. 2004 Nov;131(21):5417-27. Epub 2004 Oct 6.
Epub:
Not Epub
Abstract:
During development, the role of the phosphatidylserine receptor (PSR) in the removal of apoptotic cells that have died is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hong JR, Lin GH, Lin CJ, Wang WP, Lee CC, Lin TL, Wu JL. Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish. Development. 2004 Nov;131(21):5417-27. Epub 2004 Oct 6..

Phosphorylation-Dependent Regulation of PSF by GSK3 Controls CD45 Alternative Splicing

Authors:
Heyd F, Lynch KW
Citation:
Molecular Cell. 2010 Oct 8;40(1):126-37
Epub:
Not Epub
Abstract:
Signal-induced alternative splicing of the CD45 gene in human T cells is essential for proper immune function. Skipping of the...
Delivery Method:
Electroporation
Organism or Cell Type:
cell culture: JSL1 (lineage from Jurkat cells)
Citation Extract:
Heyd F, Lynch KW. Phosphorylation-Dependent Regulation of PSF by GSK3 Controls CD45 Alternative Splicing. Molecular Cell. 2010 Oct 8;40(1):126-37.

Photoporation of Biomolecules into Single Cells in Living Vertebrate Embryos Induced by a Femtosecond Laser Amplifier

Authors:
Hosokawa Y, Ochi H, Iino T, Hiraoka A, Tanaka M
Citation:
PLoS ONE. 2011;6(11):e27677. doi:10.1371/journal.pone.0027677
Epub:
Not Epub
Abstract:
Introduction of biomolecules into cells in living animals is one of the most important techniques in molecular and...
Delivery Method:
Photoporation
Organism or Cell Type:
zebrafish
Citation Extract:
Hosokawa Y, Ochi H, Iino T, Hiraoka A, Tanaka M. Photoporation of Biomolecules into Single Cells in Living Vertebrate Embryos Induced by a Femtosecond Laser Amplifier. PLoS ONE. 2011;6(11):e27677. doi:10.1371/journal.pone.0027677.

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