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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex

Authors:
Ishitani T, Hirao T, Suzuki M, Isoda M, Ishitani S, Harigaya K, Kitagawa M, Matsumoto K, Itoh M
Citation:
Nat Cell Biol. 2010 Mar;12(3):278-85. doi: 10.1038/ncb2028. Epub 2010 Jan 31.
Epub:
Not Epub
Abstract:
The Notch signalling pathway has a crucial function in determining cell fates in multiple tissues within metazoan organisms. On...
Organism or Cell Type:
zebrafish
Citation Extract:
Ishitani T, Hirao T, Suzuki M, Isoda M, Ishitani S, Harigaya K, Kitagawa M, Matsumoto K, Itoh M. Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex. Nat Cell Biol. 2010 Mar;12(3):278-85. doi: 10.1038/ncb2028. Epub 2010 Jan 31..

Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability

Authors:
Ishitani T, Matsumoto K, Chitnis AB, Itoh M
Citation:
Nat Cell Biol. 2005 Nov;7(11):1106-12
Epub:
Not Epub
Abstract:
Nrarp (Notch-regulated ankyrin repeat protein) is a small protein that has two ankyrin repeats. Although Nrarp is known to be...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ishitani T, Matsumoto K, Chitnis AB, Itoh M. Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability. Nat Cell Biol. 2005 Nov;7(11):1106-12.

Phosphorodiamidate morpholino oligomers: favorable properties for sequence-specific gene inactivation

Authors:
Iversen PL
Citation:
Curr Opin Mol Ther 2001 Jun;3(3):235-8
Epub:
Not Epub
Abstract:
The phosphorodiamidate morpholino oligomers (PMOs) are a distinct class of oligonucleotide analogs. They bind to RNA and...
Citation Extract:
Iversen PL. Phosphorodiamidate morpholino oligomers: favorable properties for sequence-specific gene inactivation. Curr Opin Mol Ther 2001 Jun;3(3):235-8.

Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells

Authors:
Ishioka S, Ezaka Y, Umemura K, Hayashi T, Endo T, Saito T
Citation:
Int J Med Sci. 2006 Dec 29;4(1):36-44
Epub:
Not Epub
Abstract:
Preeclampsia is often accompanied by hypoxia of the placenta and this condition induces apoptosis in trophoblastic cells. The...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: Human JAR choriocarcinoma
Citation Extract:
Ishioka S, Ezaka Y, Umemura K, Hayashi T, Endo T, Saito T. Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells. Int J Med Sci. 2006 Dec 29;4(1):36-44.

PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis

Authors:
Izaguirre DI, Zhu W, Hai T, Cheung HC, Krahe R, Cote GJ
Citation:
Mol Carcinog. 2012 Nov;51(11):895-906. doi: 10.1002/mc.20859. Epub 2011 Oct 4.
Epub:
Not Epub
Abstract:
Aberrant RNA splicing is thought to play a key role in tumorigenesis. The assessment of its specific contributions is limited...
Organism or Cell Type:
cell culture: glioblastoma (GBM) cell line
Citation Extract:
Izaguirre DI, Zhu W, Hai T, Cheung HC, Krahe R, Cote GJ. PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis. Mol Carcinog. 2012 Nov;51(11):895-906. doi: 10.1002/mc.20859. Epub 2011 Oct 4..

RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome

Authors:
Isken A, Golczak M, Oberhauser V, Hunzelmann S, Driever W, Imanishi Y, Palczewski K, von Lintig J
Citation:
Cell Metab. 2008 Mar;7(3):258-68
Epub:
Not Epub
Abstract:
The cellular uptake of vitamin A from its RBP4-bound circulating form (holo-RBP4) is a homeostatic process that evidently...
Organism or Cell Type:
zebrafish
Citation Extract:
Isken A, Golczak M, Oberhauser V, Hunzelmann S, Driever W, Imanishi Y, Palczewski K, von Lintig J. RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome. Cell Metab. 2008 Mar;7(3):258-68.

Self-regulation of the head-inducing properties of the Spemann organizer

Authors:
Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S
Citation:
Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15354-9. Epub 2012 Sep 4.
Epub:
Not Epub
Abstract:
The Spemann organizer stands out from other signaling centers of the embryo because of its broad patterning effects. It defines...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S. Self-regulation of the head-inducing properties of the Spemann organizer. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15354-9. Epub 2012 Sep 4..

Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo

Authors:
Isken A, Holzschuh J, Lampert JM, Fischer L, Oberhauser V, Palczewski K, von Lintig J
Citation:
J Biol Chem. 2007 Jan 12;282(2):1144-51. Epub 2006 Nov 10
Epub:
Not Epub
Abstract:
For vertebrate development, vitamin A (all-trans retinol) is required in quantitative different amounts and spatiotemporal...
Organism or Cell Type:
zebrafish
Citation Extract:
Isken A, Holzschuh J, Lampert JM, Fischer L, Oberhauser V, Palczewski K, von Lintig J. Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo. J Biol Chem. 2007 Jan 12;282(2):1144-51. Epub 2006 Nov 10.

The extracellular signal-regulated kinase-mitogen-activated protein kinase pathway phosphorylates and targets Cdc25A for SCF beta-TrCP-dependent degradation for cell cycle arrest

Authors:
Isoda M, Kanemori Y, Nakajo N, Uchida S, Yamashita K, Ueno H, Sagata N
Citation:
Mol Biol Cell. 2009 Apr;20(8):2186-95. Epub 2009 Feb 25
Epub:
Not Epub
Abstract:
The extracellular signal-regulated kinase (ERK) pathway is generally mitogenic, but, upon strong activation, it causes cell...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Isoda M, Kanemori Y, Nakajo N, Uchida S, Yamashita K, Ueno H, Sagata N. The extracellular signal-regulated kinase-mitogen-activated protein kinase pathway phosphorylates and targets Cdc25A for SCF beta-TrCP-dependent degradation for cell cycle arrest. Mol Biol Cell. 2009 Apr;20(8):2186-95. Epub 2009 Feb 25.

Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake

Authors:
Isenberg JS, Jia Y, Fukuyama J, Switzer CH, Wink DA, Roberts DD
Citation:
J. Biol. Chem., May 2007; 282: 15404 - 15415.
Epub:
Not Epub
Abstract:
Although CD36 is generally recognized to be an inhibitory signaling receptor for thrombospondin-1 (TSP1), the molecular...
Citation Extract:
Isenberg JS, Jia Y, Fukuyama J, Switzer CH, Wink DA, Roberts DD. Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake. J. Biol. Chem., May 2007; 282: 15404 - 15415..

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