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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
ATF6α/β-mediated Adjustment of ER Chaperone Levels Is Essential for Development of the Notochord in Medaka Fish
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Citation:
Mol Biol Cell. 2013 May;24(9):1387-95. doi: 10.1091/mbc.E12-11-0830. Epub 2013 Feb 27. Epub:
Not Epub Abstract:
ATF6α and ATF6β are membrane-bound transcription factors which are activated by regulated intramembrane proteolysis in response... Delivery Method:
Microinjection Organism or Cell Type:
medaka Citation Extract: Ishikawa T, Okada T, Ishikawa-Fujiwara T, Todo T, Kamei Y, Shigenobu S, Tanaka M, Saito TL, Yoshimura J, Morishita S, Toyoda A, Sakaki Y, Taniguchi Y, Takeda S, Mori K. ATF6α/β-mediated Adjustment of ER Chaperone Levels Is Essential for Development of the Notochord in Medaka Fish. Mol Biol Cell. 2013 May;24(9):1387-95. doi: 10.1091/mbc.E12-11-0830. Epub 2013 Feb 27.. |
BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carboplatin
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Citation:
Oral Oncol. 2002 Dec;38(8):752-6 Epub:
Not Epub Abstract:
Carboplatin (CBDCA) has been widely used for the treatment of oral squamous cell carcinoma (SCC). The Bcl-2 family member Bcl-... Delivery Method:
Scrape Delivery Organism or Cell Type:
cell culture: squamous cell carcinoma Citation Extract: Itoh M, Noutomi T, Chiba H, Mizuguchi J. BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carboplatin. Oral Oncol. 2002 Dec;38(8):752-6. |
Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts.
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Citation:
Ann. Surg. 247(1):180-190, 2008. Epub:
Not Epub Abstract:
BACKGROUND: Skin graft survival and healing requires rapid restoration of blood flow to the avascular graft. Failure or delay... Delivery Method:
in vivo: injection Organism or Cell Type:
mice Citation Extract: Isenberg JS, Pappan LK, Romeo MJ, Abu-Asab M, Tsokos M, Wink DA, Frazier WA, Roberts DD. Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts.. Ann. Surg. 247(1):180-190, 2008.. |
Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia.
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Citation:
Arterioscler. Thromb. Vasc. Biol. 27:2582-2588, 2007 Epub:
Not Epub Abstract:
OBJECTIVE: Decreased blood flow secondary to peripheral vascular disease underlies a significant number of chronic diseases... Delivery Method:
In vitro: transfection; in vivo: intramuscular injection Organism or Cell Type:
mice Citation Extract: Isenberg JS, Hyodo F, Pappan LK, Abu-Asab M, Tsokos M, Krishna MC, Frazier WA, Roberts DD. Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia.. Arterioscler. Thromb. Vasc. Biol. 27:2582-2588, 2007. |
Cellular Uptake of Neutral Phosphorodiamidate Morpholino Oligomers
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Citation:
Curr Pharm Biotechnol. 2009 Sep;10(6):579-88. Epub 2009 Sep 1. Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMO), which have a neutral chemistry, are extensively being used as tools for... Organism or Cell Type:
cell culture Citation Extract: Iversen PL, Aird KM, Wu R, Morse MM, Devi GR. Cellular Uptake of Neutral Phosphorodiamidate Morpholino Oligomers. Curr Pharm Biotechnol. 2009 Sep;10(6):579-88. Epub 2009 Sep 1.. |
Close association of carbonic anhydrase (CA2a & CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake
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Citation:
Frontiers in Physiology. 2013;4(59) doi:10.3389/fphys.2013.00059 Epub:
Not Epub Abstract:
Freshwater (FW) fishes actively absorb salt from their environment to tolerate low salinities. We previously reported that... Organism or Cell Type:
zebrafish Citation Extract: Ito Y, Kobayashi S, Nakamura N, Esaki M, Miyagi H, Hoshijima K, Hirose S. Close association of carbonic anhydrase (CA2a & CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake. Frontiers in Physiology. 2013;4(59) doi:10.3389/fphys.2013.00059. |
Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation
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Citation:
Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769. Epub 2010 Aug 16. Epub:
Not Epub Abstract:
Hypopigmentation is a feature of copper deficiency in humans, as caused by mutation of the copper (Cu(2+)) transporter ATP7A in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ishizaki H, Spitzer M, Wildenhain J, Anastasaki C, Zeng Z, Dolma S, Shaw M, Madsen E, Gitlin J, Marais R, Tyers M, Patton EE. Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769. Epub 2010 Aug 16.. |
Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses
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Citation:
J Biol Chem. 2009 Jan 9;284(2):1116-25. Epub 2008 Nov 11 Epub:
Not Epub Abstract:
Thrombospondin-1 regulates nitric oxide (NO) signaling in vascular cells via CD47. Because CD47 binding motifs are conserved in... Organism or Cell Type:
cell culture: primary TSP1-null vascular cells Citation Extract: Isenberg JS, Annis DS, Pendrak ML, Ptaszynska M, Frazier WA, Mosher DF, Roberts DD. Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses. J Biol Chem. 2009 Jan 9;284(2):1116-25. Epub 2008 Nov 11. |
Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections
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Citation:
Viruses. 2012;4(11):2806-2830. doi:10.3390/v4112806 Epub:
Not Epub Abstract:
There are no currently approved treatments for filovirus infections. In this study we report the discovery process which led to... Organism or Cell Type:
Ebola and Marburg virus, various hosts Citation Extract: Iversen PL, Warren TK, Wells JB, Garza NL, Mourich DV, Welch LS, Panchal RG, Bavari S. Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections. Viruses. 2012;4(11):2806-2830. doi:10.3390/v4112806. |
Effect of morpholino antisense oligonucleotide against lumican mRNA in human embryonic kidney (HEK) 293 cells
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Citation:
Pathol Int. 2004 Feb; 54(2): 77-81 Epub:
Not Epub Abstract:
Lumican is a member of the small-leucine-rich proteoglycan (SLRP) family and is overexpressed during wound healing of the... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: human embryonic kidney (HEK 293) Citation Extract: Ishiwata T, Fujii T, Ishiwata S, Ikegawa S, Naito Z. Effect of morpholino antisense oligonucleotide against lumican mRNA in human embryonic kidney (HEK) 293 cells. Pathol Int. 2004 Feb; 54(2): 77-81. |