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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Identification of a primary target of thalidomide teratogenicity
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Citation:
Science. 2010 Mar 12;327(5971):1345-50 Epub:
Not Epub Abstract:
Half a century ago, thalidomide was widely prescribed to pregnant women as a sedative but was found to be teratogenic, causing... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ito T, Ando H, Suzuki T, Ogura T, Hotta K, Imamura Y, Yamaguchi Y, Handa H. Identification of a primary target of thalidomide teratogenicity. Science. 2010 Mar 12;327(5971):1345-50. |
In vivo Applications of Morpholino Oligonucleotides
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Citation:
Gene and Cell Therapy: Therapeutic Mechanisms and Strategies 3rd ed., Ed: Templeton NS; CRC Press, 2008 Epub:
Not Epub Abstract:
Abstract not available Citation Extract: Isenberg JS, Frazier WA, Roberts DD. In vivo Applications of Morpholino Oligonucleotides. Gene and Cell Therapy: Therapeutic Mechanisms and Strategies 3rd ed., Ed: Templeton NS; CRC Press, 2008. |
Increasing survival of ischemic tissue by targeting CD47
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Citation:
Circ. Res. 100:712-720, 2007 Epub:
Not Epub Abstract:
Thrombospondin-1 (TSP1) limits the angiogenic and vasodilator activities of NO. This activity of TSP1 can be beneficial in some... Delivery Method:
in vivo: injection Organism or Cell Type:
mice and cell culture Citation Extract: Isenberg JS, Romeo MJ, Abu-Asab M, Tsokos M, Oldenborg A, Pappan L, Wink DA, Frazier WA, Roberts DD. Increasing survival of ischemic tissue by targeting CD47. Circ. Res. 100:712-720, 2007. |
Local application of antisense for prevention of restenosis
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Citation:
Methods Mol Med. 2004;106:37-50 Epub:
Not Epub Abstract:
In 1977, percutaneous transluminal coronary angioplasty (PTCA) was first introduced, and it has become an effective treatment... Citation Extract: Iversen PL, Kipshidze N, Moses JW, Leon MB. Local application of antisense for prevention of restenosis. Methods Mol Med. 2004;106:37-50. |
Logic functions of the genomic cis-regulatory code
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Citation:
Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):4954-9. Epub 2005 Mar 23. Review Epub:
Not Epub Abstract:
cis-Regulatory modules that control developmental gene expression process the regulatory inputs provided by the transcription... Citation Extract: Istrail S, Davidson EH. Logic functions of the genomic cis-regulatory code. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):4954-9. Epub 2005 Mar 23. Review. |
Macrophage migration inhibitory factor (MIF) is essential for development of zebrafish, Danio rerio
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Citation:
Dev Comp Immunol. 2008;32(6):664-72. Epub 2007 Nov 20. Epub:
Not Epub Abstract:
Macrophage migration inhibitory factor (MIF) was discovered as the first cytokine that inhibited the random migration of... Organism or Cell Type:
zebrafish Citation Extract: Ito K, Yoshiura Y, Ototake M, Nakanishi T. Macrophage migration inhibitory factor (MIF) is essential for development of zebrafish, Danio rerio. Dev Comp Immunol. 2008;32(6):664-72. Epub 2007 Nov 20. . |
Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling
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Citation:
Development. 2006 Oct;133(19):3919-28. Epub 2006 Aug 30 Epub:
Not Epub Abstract:
A growing number of integral inner nuclear membrane (INM) proteins have been implicated in diverse cellular functions. Man1, an... Organism or Cell Type:
Xenopus Citation Extract: Ishimura A, Ng JK, Taira M, Young SG, Osada S. Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. Development. 2006 Oct;133(19):3919-28. Epub 2006 Aug 30. |
Manipulation of zebrafish embryogenesis by phosphorodiamidate morpholino oligomers indicates minimal non-specific teratogenesis
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Citation:
Curr Opin Mol Ther 2005 7(2):104-8 Epub:
Not Epub Abstract:
The incidence of teratogenicity caused by therapeutic agents is a significant concern in drug development. Approaches to... Organism or Cell Type:
zebrafish Citation Extract: Iversen PL, Newbry S. Manipulation of zebrafish embryogenesis by phosphorodiamidate morpholino oligomers indicates minimal non-specific teratogenesis. Curr Opin Mol Ther 2005 7(2):104-8. |
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta
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Citation:
Dev Cell. 2003 Jan;4(1):67-82 Epub:
Not Epub Abstract:
Lateral inhibition, mediated by Notch signaling, leads to the selection of cells that are permitted to become neurons within... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Itoh M, Kim CH, Palardy G, Oda T, Jiang YJ, Maust D, Yeo SY, Lorick K, Wright GJ, Ariza-McNaughton L, Weissman AM, Lewis J, Chandrasekharappa SC, Chitnis AB. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev Cell. 2003 Jan;4(1):67-82. |
Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins
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Citation:
Dev Biol. 2005 Feb 1;278(1):208-19. Epub:
Not Epub Abstract:
Mechanisms that regulate the size and shape of bony structures are largely unknown. The molecular identification of the fin... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Iovine MK, Higgins EP, Hindes A, Coblitz B, Johnson SL. Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins. Dev Biol. 2005 Feb 1;278(1):208-19.. |