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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function

Authors:
Hyvarinen J, Parikka M, Sormunen R, Ramet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P
Citation:
J Biol Chem. 2010 Dec 31;285(53):42023-32. doi: 10.1074/jbc.M110.145904. Epub 2010 Oct 15.
Epub:
Not Epub
Abstract:
Prolyl 4-hydroxylases (P4Hs) catalyze the hydroxylation of collagens and hypoxia inducible factor (HIF) α subunits. We studied...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hyvarinen J, Parikka M, Sormunen R, Ramet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P. Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function. J Biol Chem. 2010 Dec 31;285(53):42023-32. doi: 10.1074/jbc.M110.145904. Epub 2010 Oct 15..

Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism

Authors:
Incardona JP, Day HL, Collier TK, Scholz NL
Citation:
Toxicol Appl Pharmacol. 2006 Dec 15;217(3):308-21. Epub 2006 Oct 7
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) derived from fossil fuels are ubiquitous contaminants and occur in aquatic habitats as...
Delivery Method:
in which tissue uptake is dependent solely on hydrophobicity and toxicity is mediated through non-specific partitioning into lipid bilayers. As part of a systematic analysis of mechanisms of PAH developmental toxicity in zebrafish
Organism or Cell Type:
we show here that three tetracyclic PAHs (pyrene
Citation Extract:
Incardona JP, Day HL, Collier TK, Scholz NL. Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism. Toxicol Appl Pharmacol. 2006 Dec 15;217(3):308-21. Epub 2006 Oct 7.

Different roles for KIF17 and kinesin II in photoreceptor development and maintenance

Authors:
Insinna C, Humby M, Sedmak T, Wolfrum U, Besharse JC
Citation:
Dev Dyn. 2009 Sep;238(9):2211-22
Epub:
Not Epub
Abstract:
Kinesin 2 family members are involved in transport along ciliary microtubules. In Caenorhabditis elegans channel cilia, kinesin...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Humby M, Sedmak T, Wolfrum U, Besharse JC. Different roles for KIF17 and kinesin II in photoreceptor development and maintenance. Dev Dyn. 2009 Sep;238(9):2211-22.

Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notochord in Ciona savignyi embryos

Authors:
Imai KS, Satoh N, Satou Y
Citation:
Development. 2002 Apr 1;129(7):1729-38
Epub:
Not Epub
Abstract:
In early Ciona savignyi embryos, nuclear localization of beta-catenin is the first step of endodermal cell specification, and...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona savignyi
Citation Extract:
Imai KS, Satoh N, Satou Y. Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notochord in Ciona savignyi embryos. Development. 2002 Apr 1;129(7):1729-38.

Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis

Authors:
Idris MM, Thorndyke MC, Brown ER
Citation:
Invert Neurosci. 2013 Jun 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington's...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Idris MM, Thorndyke MC, Brown ER. Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis. Invert Neurosci. 2013 Jun 25. [Epub ahead of print].

Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks

Authors:
Imai KS, Hino K, Yagi K, Satoh N, Satou Y
Citation:
Development. 2004 Aug;131(16):4047-58.
Epub:
Not Epub
Abstract:
Achieving a real understanding of animal development obviously requires a comprehensive rather than partial identification of...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Imai KS, Hino K, Yagi K, Satoh N, Satou Y. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Development. 2004 Aug;131(16):4047-58..

Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system

Authors:
Imai KS, Stolfi A, Levine M, Satou Y
Citation:
Development. 2009 Jan;136(2):285-93. Epub 2008 Dec 15
Epub:
Not Epub
Abstract:
The tripartite organization of the central nervous system (CNS) may be an ancient character of the bilaterians. However, the...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis and Ciona savignyi
Citation Extract:
Imai KS, Stolfi A, Levine M, Satou Y. Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system. Development. 2009 Jan;136(2):285-93. Epub 2008 Dec 15.

Identification and characterization of the zebrafish pharyngeal arch-specific enhancer for the basic helix-loop-helix transcription factor Hand2

Authors:
Iklé JM, Artinger KB, Clouthier DE
Citation:
Dev Biol. 2012 Aug 1;368(1):118-26. doi: 10.1016/j.ydbio.2012.05.003. Epub 2012 May 14.
Epub:
Not Epub
Abstract:
The development of the vertebrate jaw relies on a network of transcription factors that patterns the dorsal-ventral axis of the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iklé JM, Artinger KB, Clouthier DE. Identification and characterization of the zebrafish pharyngeal arch-specific enhancer for the basic helix-loop-helix transcription factor Hand2. Dev Biol. 2012 Aug 1;368(1):118-26. doi: 10.1016/j.ydbio.2012.05.003. Epub 2012 May 14..

In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin

Authors:
Hyde DR, Godwin AR, Thummel R
Citation:
J Vis Exp. 2012;(61):e3632 DOI: 10.3791/3632
Epub:
Not Epub
Abstract:
<snip – database limit> The zebrafish fin is a relatively simple appendage that is easily manipulated to study multiple...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Hyde DR, Godwin AR, Thummel R. In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin. J Vis Exp. 2012;(61):e3632 DOI: 10.3791/3632.

Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors

Authors:
Insinna C, Besharse JC
Citation:
Dev Dyn. 2008 Aug;237(8):1982-92. Review
Epub:
Not Epub
Abstract:
Analysis of the other segments of rod and cone photoreceptors in vertebrates has provided a rich molecular understanding of how...
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Besharse JC. Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors. Dev Dyn. 2008 Aug;237(8):1982-92. Review.

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