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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses

Authors:
Je HS, Yang F, Ji Y, Nagappan G, Hempstead BL, Lu B
Citation:
Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15924-9. Epub 2012 Sep 10.
Epub:
Not Epub
Abstract:
Formation of specific neuronal connections often involves competition between adjacent axons, leading to stabilization of the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Je HS, Yang F, Ji Y, Nagappan G, Hempstead BL, Lu B. Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15924-9. Epub 2012 Sep 10..

Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression

Authors:
Jin H, Li L, Xu J, Zhen F, Zhu L, Liu PP, Zhang M, Zhang W, Wen Z
Citation:
Blood. 2012;119(22):5239-49. doi: 10.1182/blood-2011-12-398362
Epub:
Not Epub
Abstract:
Proper cell fate choice in myelopoiesis is essential for generating correct numbers of distinct myeloid subsets manifesting a...
Organism or Cell Type:
zebrafish
Citation Extract:
Jin H, Li L, Xu J, Zhen F, Zhu L, Liu PP, Zhang M, Zhang W, Wen Z. Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood. 2012;119(22):5239-49. doi: 10.1182/blood-2011-12-398362.

Scube activity is necessary for Hedgehog signal transduction in vivo

Authors:
Johnson JL, Hall T, Dyson J, Sonntag C, Ayers K, Berger S, Gautier P, Mitchell C, Hollway GE, Currie PD
Citation:
Dev Biol. 2012 Aug 15;368(2):193-202. doi: 10.1016/j.ydbio.2012.05.007. Epub 2012 May 17.
Epub:
Not Epub
Abstract:
The Hedgehog (HH) signaling pathway is a central regulator of embryonic development, controlling the pattern and proliferation...
Organism or Cell Type:
zebrafish
Citation Extract:
Johnson JL, Hall T, Dyson J, Sonntag C, Ayers K, Berger S, Gautier P, Mitchell C, Hollway GE, Currie PD. Scube activity is necessary for Hedgehog signal transduction in vivo. Dev Biol. 2012 Aug 15;368(2):193-202. doi: 10.1016/j.ydbio.2012.05.007. Epub 2012 May 17..

Shp2 Knockdown and Noonan/LEOPARD Mutant Shp2-Induced Gastrulation Defects

Authors:
Jopling C, van Geemen D, den Hertog J
Citation:
PLoS Genet. 2007 Dec 21;3(12):e225 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Shp2 is a cytoplasmic protein-tyrosine phosphatase that is essential for normal development. Activating and inactivating...
Organism or Cell Type:
zebrafish
Citation Extract:
Jopling C, van Geemen D, den Hertog J. Shp2 Knockdown and Noonan/LEOPARD Mutant Shp2-Induced Gastrulation Defects. PLoS Genet. 2007 Dec 21;3(12):e225 [Epub ahead of print] .

Smad2 and Smad3 are required for mesendoderm induction by TGF-beta /Nodal signals in zebrafish

Authors:
Jia S, Ren Z, Li X, Zheng Y, Meng A
Citation:
J Biol Chem. 2007 Nov 19; [Epub ahead of print]
Epub:
Not Epub
Abstract:
The TGF-beta ligands Nodal, Activin, and Vg1 play important roles in mesendoderm induction and patterning during vertebrate...
Organism or Cell Type:
zebrafish
Citation Extract:
Jia S, Ren Z, Li X, Zheng Y, Meng A. Smad2 and Smad3 are required for mesendoderm induction by TGF-beta /Nodal signals in zebrafish. J Biol Chem. 2007 Nov 19; [Epub ahead of print].

Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene regulation in Xenopus

Authors:
Jallow Z, Jacobi UG, Weeks DL, Dawid IB, Veenstra GJ
Citation:
Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13525-30.
Epub:
Not Epub
Abstract:
The general transcription factor TATA-binding protein (TBP) is a key initiation factor involved in transcription by all three...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Jallow Z, Jacobi UG, Weeks DL, Dawid IB, Veenstra GJ. Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene regulation in Xenopus. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13525-30..

Suppression of ADAM 10-induced Delta-1 Shedding Inhibits Cell Proliferation During the Chondro-Inhibitory Action of TGF-beta3

Authors:
Jin EJ, Choi YA, Sonn JK, Kang SS
Citation:
Mol Cells. 2007 Aug 31;24(1):139-47
Epub:
Not Epub
Abstract:
Although transforming growth factors (TGFs) are implicated in the process of endochondral ossification, which is initiated by...
Delivery Method:
Electroporation
Organism or Cell Type:
cell culture: chick leg bud mesenchyme
Citation Extract:
Jin EJ, Choi YA, Sonn JK, Kang SS. Suppression of ADAM 10-induced Delta-1 Shedding Inhibits Cell Proliferation During the Chondro-Inhibitory Action of TGF-beta3. Mol Cells. 2007 Aug 31;24(1):139-47.

Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligomers in the Muscles of mdx Mice

Authors:
Jearawiriyapaisarn N, Moulton HM, Buckley B, Roberts J, Sazani P, Fucharoen S, Iversen PL, Kole R
Citation:
Mol Ther. 2008 Sep;16(9):1624-9. Epub 2008 Jun 10
Epub:
Not Epub
Abstract:
Cell-penetrating peptides (CPPs), containing arginine (R), 6-aminohexanoic acid (X), and/or beta-alanine (B) conjugated to...
Delivery Method:
peptide-coupled
Organism or Cell Type:
MDX mice
Citation Extract:
Jearawiriyapaisarn N, Moulton HM, Buckley B, Roberts J, Sazani P, Fucharoen S, Iversen PL, Kole R. Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligomers in the Muscles of mdx Mice. Mol Ther. 2008 Sep;16(9):1624-9. Epub 2008 Jun 10.

Switching from single-stranded to double-stranded DNA limits the unwinding processivity of ring-shaped T7 DNA helicase

Authors:
Jeong YJ, Rajagopal V, Patel SS
Citation:
Nucl Acids Res. 2013;[Epub ahead of print] doi:10.1093/nar/gkt133
Epub:
Not Epub
Abstract:
Phage T7 helicase unwinds double-stranded DNA (dsDNA) by encircling one strand while excluding the complementary strand from...
Delivery Method:
in vitro: enzymology
Organism or Cell Type:
Bacteriophage T7
Citation Extract:
Jeong YJ, Rajagopal V, Patel SS. Switching from single-stranded to double-stranded DNA limits the unwinding processivity of ring-shaped T7 DNA helicase. Nucl Acids Res. 2013;[Epub ahead of print] doi:10.1093/nar/gkt133 .

The 48 kDa alternative translation isoform of PP2A:B56epsilon is required for Wnt Signaling during Midbrain-Hindbrain Boundary Formation

Authors:
Jin Z, Shi J, Saraf A, Mei W, Zhu GZ, Strack S, Yang J
Citation:
J Biol Chem. 2009 Mar 13;284(11):7190-200. doi: 10.1074/jbc.M807907200. Epub 2009 Jan 7.
Epub:
Not Epub
Abstract:
Alternative translation is an underappreciated post-transcriptional regulation mechanism. Although only a small number of genes...
Organism or Cell Type:
Xenopus
Citation Extract:
Jin Z, Shi J, Saraf A, Mei W, Zhu GZ, Strack S, Yang J. The 48 kDa alternative translation isoform of PP2A:B56epsilon is required for Wnt Signaling during Midbrain-Hindbrain Boundary Formation. J Biol Chem. 2009 Mar 13;284(11):7190-200. doi: 10.1074/jbc.M807907200. Epub 2009 Jan 7..

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