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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

An essential role of a FoxD gene in notochord induction in Ciona embryos

Authors:
Imai KS, Satoh N, Satou Y
Citation:
Development. 2002 Jul;129(14):3441-53
Epub:
Not Epub
Abstract:
A key issue for understanding the early development of the chordate body plan is how the endoderm induces notochord formation....
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona savignyi
Citation Extract:
Imai KS, Satoh N, Satou Y. An essential role of a FoxD gene in notochord induction in Ciona embryos. Development. 2002 Jul;129(14):3441-53.

Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development

Authors:
Insinna C, Baye LM, Amsterdam A, Besharse JC, Link BA
Citation:
Neural Dev. 2010 Apr 22;5(1):12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Photoreceptors of the retina are highly compartmentalized cells that function as the primary sensory...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Baye LM, Amsterdam A, Besharse JC, Link BA. Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. Neural Dev. 2010 Apr 22;5(1):12. [Epub ahead of print].

Aryl Hydrocarbon Receptor-Independent Toxicity Of Weathered Crude Oil During Fish Development

Authors:
Incardona JP, Carls MG, Teraoka H, Sloan CA, Collier TK, Scholz NL
Citation:
Environ Health Perspect. 2005 Dec;113(12):1755-62.
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs), derived largely from fossil fuels and their combustion, are pervasive contaminants in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Incardona JP, Carls MG, Teraoka H, Sloan CA, Collier TK, Scholz NL. Aryl Hydrocarbon Receptor-Independent Toxicity Of Weathered Crude Oil During Fish Development. Environ Health Perspect. 2005 Dec;113(12):1755-62..

Cis-acting transcriptional repression establishes a sharp boundary in chordate embryos

Authors:
Imai KS, Daido Y, Kusakabe TG, Satou Y
Citation:
Science. 2012 Aug 24;337(6097):964-7
Epub:
Not Epub
Abstract:
The function of bone morphogenetic protein (BMP) signaling in dorsoventral (DV) patterning of animal embryos is conserved among...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Imai KS, Daido Y, Kusakabe TG, Satou Y. Cis-acting transcriptional repression establishes a sharp boundary in chordate embryos. Science. 2012 Aug 24;337(6097):964-7.

colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis

Authors:
Ignatius MS, Moose HE, El-Hodiri HM, Henion PD
Citation:
Dev Biol. 2008 Jan 15;313(2):568-83. Epub 2007 Nov 9
Epub:
Not Epub
Abstract:
Neural crest-derived pigment cell development has been used extensively to study cell fate specification, migration,...
Organism or Cell Type:
zebrafish
Citation Extract:
Ignatius MS, Moose HE, El-Hodiri HM, Henion PD. colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis. Dev Biol. 2008 Jan 15;313(2):568-83. Epub 2007 Nov 9.

Cytokine knockouts in reproduction: the use of gene ablation to dissect roles of cytokines in reproductive biology.

Authors:
Ingman WV, Jones RL
Citation:
Hum Reprod Update 2008 Mar-Apr;14(2):179-92. Epub 2007 Dec 6.
Epub:
Not Epub
Abstract:
Cytokines play many diverse and important roles in reproductive biology, and dissecting the complex interactions between these...
Citation Extract:
Ingman WV, Jones RL. Cytokine knockouts in reproduction: the use of gene ablation to dissect roles of cytokines in reproductive biology. . Hum Reprod Update 2008 Mar-Apr;14(2):179-92. Epub 2007 Dec 6..

Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons.

Authors:
Incardona JP, Collier TK, Scholz NL
Citation:
Toxicol Appl Pharmacol. 2004 Apr 15;196(2):191-205
Epub:
Not Epub
Abstract:
Fish embryos exposed to complex mixtures of polycyclic aromatic hydrocarbons (PAHs) from petrogenic sources show a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Incardona JP, Collier TK, Scholz NL. Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons.. Toxicol Appl Pharmacol. 2004 Apr 15;196(2):191-205.

Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function

Authors:
Hyvarinen J, Parikka M, Sormunen R, Ramet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P
Citation:
J Biol Chem. 2010 Dec 31;285(53):42023-32. doi: 10.1074/jbc.M110.145904. Epub 2010 Oct 15.
Epub:
Not Epub
Abstract:
Prolyl 4-hydroxylases (P4Hs) catalyze the hydroxylation of collagens and hypoxia inducible factor (HIF) α subunits. We studied...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hyvarinen J, Parikka M, Sormunen R, Ramet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P. Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function. J Biol Chem. 2010 Dec 31;285(53):42023-32. doi: 10.1074/jbc.M110.145904. Epub 2010 Oct 15..

Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism

Authors:
Incardona JP, Day HL, Collier TK, Scholz NL
Citation:
Toxicol Appl Pharmacol. 2006 Dec 15;217(3):308-21. Epub 2006 Oct 7
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) derived from fossil fuels are ubiquitous contaminants and occur in aquatic habitats as...
Delivery Method:
in which tissue uptake is dependent solely on hydrophobicity and toxicity is mediated through non-specific partitioning into lipid bilayers. As part of a systematic analysis of mechanisms of PAH developmental toxicity in zebrafish
Organism or Cell Type:
we show here that three tetracyclic PAHs (pyrene
Citation Extract:
Incardona JP, Day HL, Collier TK, Scholz NL. Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism. Toxicol Appl Pharmacol. 2006 Dec 15;217(3):308-21. Epub 2006 Oct 7.

Different roles for KIF17 and kinesin II in photoreceptor development and maintenance

Authors:
Insinna C, Humby M, Sedmak T, Wolfrum U, Besharse JC
Citation:
Dev Dyn. 2009 Sep;238(9):2211-22
Epub:
Not Epub
Abstract:
Kinesin 2 family members are involved in transport along ciliary microtubules. In Caenorhabditis elegans channel cilia, kinesin...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Humby M, Sedmak T, Wolfrum U, Besharse JC. Different roles for KIF17 and kinesin II in photoreceptor development and maintenance. Dev Dyn. 2009 Sep;238(9):2211-22.

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