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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties
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Citation:
Transl Oncol. 2018;12(1):134-42. doi:10.1016/j.tranon.2018.09.001 Epub:
Not Epub Abstract:
The oncogene ERG encodes an ETS family transcription factor and is implicated in blood, vascular, and bone development and in... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: MG63 ( human osteoblast-like osteosarcoma) and VCaP (human prostate cancer vertebral metastasis) Citation Extract: Jumbe SL, Porazinski SR, Oltean S, Mansell JP, Vahabi B, Wilson ID, Ladomery MR. The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties. Transl Oncol. 2018;12(1):134-42. doi:10.1016/j.tranon.2018.09.001. |
Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88
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Citation:
Nat Commun. 2018 Oct 5;9(1):4099. doi: 10.1038/s41467-018-06658-4 Epub:
Not Epub Abstract:
Host pathways mediating changes in immune states elicited by intestinal microbial colonization are incompletely characterized.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koch BEV, Yang S, Lamers G, Stougaard J, Spaink HP. Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88. Nat Commun. 2018 Oct 5;9(1):4099. doi: 10.1038/s41467-018-06658-4. |
Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus
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Citation:
Development. 2018:dev.166710 doi: 10.1242/dev.166710 Epub:
Not Epub Abstract:
The pre-placodal ectoderm (PPE) is a specialized ectodermal region which gives rise to the sensory organs and other systems.... Organism or Cell Type:
Xenopus laevis Citation Extract: Watanabe T, Yamamoto T, Tsukano K, Hirano S, Horikawa A, Michiue T. Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus. Development. 2018:dev.166710 doi: 10.1242/dev.166710. |
4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish
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Citation:
PLoS One. 2018 Oct 4;13(10):e0205255. doi: 10.1371/journal.pone.0205255 Epub:
Not Epub Abstract:
During the process of synapse formation, thousands of proteins assemble at prospective sites of cell-cell communication.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fierro J Jr, Haynes DR, Washbourne P. 4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish. PLoS One. 2018 Oct 4;13(10):e0205255. doi: 10.1371/journal.pone.0205255. |
CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii
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Citation:
Front Cell Infect Microbiol. 2018;[Epub] doi:10.3389/fcimb.2018.00352 Epub:
Yes Abstract:
Toxoplasma gondii, an Apicomplexan parasite, causes significant morbidity and mortality, including severe disease in... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Toxoplasma gondii (Apicomplexan) Citation Extract: Lykins JD, Filippova EV, Halavaty AS, Minasov G, Zhou Y, Dubrovska I, Flores KJ, Ludmilla A Shuvalova LA, Ruan J, El Bissati K, Dovgin S, Roberts CW, Woods S, Moulton JD, Moulton H, McPhillie M, Muench SP, Fishwick CWG, Sabini E, Shanmugam D, Roos DS, McLeod R, Anderson WF, Ngô H. CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. Front Cell Infect Microbiol. 2018;[Epub] doi:10.3389/fcimb.2018.00352. |
Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signaling activity in leading cells
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Citation:
PNAS USA. 2018 Oct 16;115(42):E9812-E9821. doi: 10.1073/pnas.1812016115. Epub 2018 Oct 3. Epub:
Yes Abstract:
The ability of cells to collectively interpret surrounding environmental signals underpins their capacity to coordinate their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roussigné M, Wei L, Tsingos E, Kuchling F, Alkobtawi M, Tsalavouta M, Wittbrodt J, Carl M, Blader P, Wilson SW. Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signaling activity in leading cells. PNAS USA. 2018 Oct 16;115(42):E9812-E9821. doi: 10.1073/pnas.1812016115. Epub 2018 Oct 3.. |
CCAAT/enhancer-binding protein-β functions as a negative regulator of Wnt/β-catenin signaling through activation of AXIN1 gene expression
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Citation:
Cell Death & Disease. 2018;9:1023. doi:10.1038/s41419-018-1072-1 Epub:
Not Epub Abstract:
Axin1, a concentration-limiting component of the β-catenin destruction complex, negatively regulates the Wnt/β-catenin pathway... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Park S, Lee M-S, Gwak J, Choi T-I, Lee Y, Ju BG, Kim C-H, Oh S. CCAAT/enhancer-binding protein-β functions as a negative regulator of Wnt/β-catenin signaling through activation of AXIN1 gene expression. Cell Death & Disease. 2018;9:1023. doi:10.1038/s41419-018-1072-1. |
Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment
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Citation:
Hum Mol Genet. 2018 Oct 2. doi: 10.1093/hmg/ddy346. [Epub ahead of print] Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature... Delivery Method:
peptide-linked Organism or Cell Type:
mice mdx Citation Extract: Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment. Hum Mol Genet. 2018 Oct 2. doi: 10.1093/hmg/ddy346. [Epub ahead of print]. |
Poor Splice-Site Recognition in a Humanized Zebrafish Knockin Model for the Recurrent Deep-Intronic c.7595-2144A>G Mutation in USH2A
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Citation:
Zebrafish. 2018 Oct 3. doi: 10.1089/zeb.2018.1613. [Epub ahead of print] Epub:
Yes Abstract:
The frequent deep-intronic c.7595-2144A>G mutation in intron 40 of USH2A generates a high-quality splice donor site,... Organism or Cell Type:
zebrafish Citation Extract: Slijkerman R, Goloborodko A, Broekman S, de Vrieze E, Hetterschijt L, Peters T, Gerits M, Kremer H, van Wijk E. Poor Splice-Site Recognition in a Humanized Zebrafish Knockin Model for the Recurrent Deep-Intronic c.7595-2144A>G Mutation in USH2A. Zebrafish. 2018 Oct 3. doi: 10.1089/zeb.2018.1613. [Epub ahead of print]. |
Regulatory cocktail for dopaminergic neurons in a protovertebrate identified by whole-embryo single-cell transcriptomics
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Citation:
Genes Dev. 2018 Sep 18. doi: 10.1101/gad.317669.118. [Epub ahead of print] Epub:
Yes Abstract:
The CNS of the protovertebrate Ciona intestinalis contains a single cluster of dopaminergic (DA) neurons, the coronet cells,... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Horie T, Horie R, Chen K, Cao C, Nakagawa M, Kusakabe TG, Satoh N, Sasakura Y, Levine M. Regulatory cocktail for dopaminergic neurons in a protovertebrate identified by whole-embryo single-cell transcriptomics. Genes Dev. 2018 Sep 18. doi: 10.1101/gad.317669.118. [Epub ahead of print]. |