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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The Rx-like Homeobox Gene (Rx-L) Is Necessary for Normal Photoreceptor Development

Authors:
Pan Y, Nekkalapudi S, Kelly LE, El-Hodiri HM
Citation:
Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4245-4253
Epub:
Not Epub
Abstract:
PURPOSE: The retinal homeobox (Rx) gene plays an essential role in retinal development. An Rx-like (Rx-L) gene from Xenopus...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pan Y, Nekkalapudi S, Kelly LE, El-Hodiri HM. The Rx-like Homeobox Gene (Rx-L) Is Necessary for Normal Photoreceptor Development. Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4245-4253.

The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish

Authors:
Osborne N, Brand-Arzamendi K, Ober EA, Jin SW, Verkade H, Holtzman NG, Yelon D, Stainier DY
Citation:
Curr Biol. 2008 Dec 9;18(23):1882-8
Epub:
Not Epub
Abstract:
The bioactive lipid sphingosine 1-phosphate (S1P) and its G protein-coupled receptors play critical roles in cardiovascular,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborne N, Brand-Arzamendi K, Ober EA, Jin SW, Verkade H, Holtzman NG, Yelon D, Stainier DY. The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. Curr Biol. 2008 Dec 9;18(23):1882-8.

The transcription factor Snail regulates osteogenic differentiation by repressing Runx2 expression

Authors:
Park SJ, Jung SH, Jogeswar G, Ryoo HM, Yook JI, Choi HS, Rhee Y, Kim CH, Lim SK
Citation:
Bone. 2010 Mar 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Osteoblasts originate from mesenchymal stem cells by the coordinated activities of different signaling pathways that regulate...
Organism or Cell Type:
zebrafish
Citation Extract:
Park SJ, Jung SH, Jogeswar G, Ryoo HM, Yook JI, Choi HS, Rhee Y, Kim CH, Lim SK. The transcription factor Snail regulates osteogenic differentiation by repressing Runx2 expression. Bone. 2010 Mar 6. [Epub ahead of print].

The transcription factors, Scl and Lmo2, act together during development of the haemangioblast in zebrafish

Authors:
Patterson LJ, Gering M, Eckfeldt CE, Green AR, Verfaillie CM, Ekker SC, Patient R
Citation:
Blood. 2007 Mar 15;109(6):2389-98. Epub 2006 Nov 7
Epub:
Not Epub
Abstract:
The transcription factors Scl and Lmo2 are crucial for development of all blood. An important early requirement for Scl in...
Organism or Cell Type:
zebrafish
Citation Extract:
Patterson LJ, Gering M, Eckfeldt CE, Green AR, Verfaillie CM, Ekker SC, Patient R. The transcription factors, Scl and Lmo2, act together during development of the haemangioblast in zebrafish. Blood. 2007 Mar 15;109(6):2389-98. Epub 2006 Nov 7.

The zebrafish as a model for human disease

Authors:
Penberthy WT, Shafizadeh E, Lin S
Citation:
Front Biosci. 2002 Jun 1;7:D1439-53
Epub:
Not Epub
Abstract:
Much of our current understanding of the function of genes modulating the normal process of embryonic development has come from...
Organism or Cell Type:
zebrafish
Citation Extract:
Penberthy WT, Shafizadeh E, Lin S. The zebrafish as a model for human disease. Front Biosci. 2002 Jun 1;7:D1439-53.

The Zebrafish fleer Gene Encodes an Essential Regulator of Cilia Tubulin Polyglutamylation

Authors:
Pathak N, Obara T, Mangos S, Liu Y, Drummond IA
Citation:
Mol Biol Cell. 2007 Nov;18(11):4353-64. Epub 2007 Aug 29
Epub:
Not Epub
Abstract:
Monitoring Editor: Stephen Doxsey Cilia and basal bodies are essential organelles for a broad spectrum of functions including...
Organism or Cell Type:
zebrafish
Citation Extract:
Pathak N, Obara T, Mangos S, Liu Y, Drummond IA. The Zebrafish fleer Gene Encodes an Essential Regulator of Cilia Tubulin Polyglutamylation. Mol Biol Cell. 2007 Nov;18(11):4353-64. Epub 2007 Aug 29.

Transdermal delivery of phosphorodiamidate Morpholino oligomers across hairless mouse skin.

Authors:
Pannier AK, Arora V, Iversen PL, Brand RM
Citation:
Int J Pharm. 2004 May 4;275(1-2):217-26.
Epub:
Not Epub
Abstract:
The skin is the largest organ in the body and an obvious route for both local and systemic drug delivery. Antisense oligomers...
Citation Extract:
Pannier AK, Arora V, Iversen PL, Brand RM. Transdermal delivery of phosphorodiamidate Morpholino oligomers across hairless mouse skin.. Int J Pharm. 2004 May 4;275(1-2):217-26..

Tubulin tyrosine ligase like genes TTLL3 and TTLL6 maintain zebrafish cilia structure and motility

Authors:
Pathak N, Austin CA, Drummond IA
Citation:
J Biol Chem. 2011 Apr 1;286(13):11685-95. Epub 2011 Jan 24.
Epub:
Not Epub
Abstract:
Tubulin posttranslational modifications generate microtubule heterogeneity and modulate microtubule function, and are catalyzed...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pathak N, Austin CA, Drummond IA. Tubulin tyrosine ligase like genes TTLL3 and TTLL6 maintain zebrafish cilia structure and motility. J Biol Chem. 2011 Apr 1;286(13):11685-95. Epub 2011 Jan 24..

Two Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Paralogs are Required for Normal Development in Zebrafish

Authors:
Ott LE, McDowell ZT, Turner PM, Law JM, Adler KB, Yoder JA, Jones SL
Citation:
Anat Rec (Hoboken). 2011 Aug 1. doi: 10.1002/ar.21453. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Myristoylated alanine-rich C-kinase substrate (MARCKS) is an actin binding protein substrate of protein kinase C (PKC) and...
Organism or Cell Type:
zebrafish
Citation Extract:
Ott LE, McDowell ZT, Turner PM, Law JM, Adler KB, Yoder JA, Jones SL. Two Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Paralogs are Required for Normal Development in Zebrafish. Anat Rec (Hoboken). 2011 Aug 1. doi: 10.1002/ar.21453. [Epub ahead of print].

Two zebrafish Notch-dependent hairy/Enhancer-of-split-related genes, her6 and her4, are required to maintain the coordination of cyclic gene expression in the presomitic mesoderm

Authors:
Pasini A, Jiang YJ, Wilkinson DG
Citation:
Development. 2004 Apr;131(7):1529-1541
Epub:
Not Epub
Abstract:
Alterations of the Delta/Notch signalling pathway cause multiple morphogenetic abnormalities in somitogenesis, including...
Delivery Method:
Microinjection and cell-free system
Organism or Cell Type:
zebrafish
Citation Extract:
Pasini A, Jiang YJ, Wilkinson DG. Two zebrafish Notch-dependent hairy/Enhancer-of-split-related genes, her6 and her4, are required to maintain the coordination of cyclic gene expression in the presomitic mesoderm. Development. 2004 Apr;131(7):1529-1541.

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