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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Role of Chd7 in Zebrafish: A Model for CHARGE Syndrome

Authors:
Patten SA, Jacobs-McDaniels NL, Zaouter C, Drapeau P, Albertson RC, Moldovan F
Citation:
PLoS ONE. 2012;7(2):e31650. doi:10.1371/journal.pone.0031650
Epub:
Not Epub
Abstract:
CHARGE syndrome is caused by mutations in the CHD7 gene. Several organ systems including the retina, cranial nerves, inner ear...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patten SA, Jacobs-McDaniels NL, Zaouter C, Drapeau P, Albertson RC, Moldovan F. Role of Chd7 in Zebrafish: A Model for CHARGE Syndrome. PLoS ONE. 2012;7(2):e31650. doi:10.1371/journal.pone.0031650.

Role of G protein-coupled estrogen receptor 1, GPER, in inhibition of oocyte maturation by endogenous estrogens in zebrafish

Authors:
Pang Y, Thomas P
Citation:
Dev Biol. 2010 Jun 15;342(2):194-206. Epub 2010 Apr 9
Epub:
Not Epub
Abstract:
Estrogen inhibition of oocyte maturation (OM) and the role of GPER (formerly known as GPR30) were investigated in zebrafish....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pang Y, Thomas P. Role of G protein-coupled estrogen receptor 1, GPER, in inhibition of oocyte maturation by endogenous estrogens in zebrafish. Dev Biol. 2010 Jun 15;342(2):194-206. Epub 2010 Apr 9.

Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling

Authors:
Park DS, Seo JH, Hong M, Choi SC
Citation:
Biochem Biophys Res Commun. 2013 Jun 3. doi:pii: S0006-291X(13)00911-X. 10.1016/j.bbrc.2013.05.104. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Wnt/β-catenin signaling pathway plays critical roles in early embryonic development, stem cell biology and human diseases...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park DS, Seo JH, Hong M, Choi SC. Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling. Biochem Biophys Res Commun. 2013 Jun 3. doi:pii: S0006-291X(13)00911-X. 10.1016/j.bbrc.2013.05.104. [Epub ahead of print].

Role of X-Delta-2 in the early neural development of Xenopus laevis

Authors:
Peres JN, Durston AJ
Citation:
Dev Dyn. 2006 Mar;235(3):802-10.
Epub:
Not Epub
Abstract:
The Drosophila Delta gene and its vertebrate homologues are ligands for the Notch receptor and are involved in a variety of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Peres JN, Durston AJ. Role of X-Delta-2 in the early neural development of Xenopus laevis. Dev Dyn. 2006 Mar;235(3):802-10..

Scl is required for dorsal aorta as well as blood formation in zebrafish embryos

Authors:
Patterson LJ, Gering M, Patient R
Citation:
Blood. 2005; 105(9): p. 3502-3511
Epub:
Not Epub
Abstract:
Blood and endothelial cells arise in close association in developing embryos, possibly from a shared precursor, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patterson LJ, Gering M, Patient R. Scl is required for dorsal aorta as well as blood formation in zebrafish embryos. Blood. 2005; 105(9): p. 3502-3511.

Sesn1 is a novel gene for left-right asymmetry and mediating nodal signaling.

Authors:
Peeters H, Voz ML, Verschueren K, De Cat B, Pendeville H, Thienpont B, Schellens A, Belmont JW, David G, Van De Ven WJ, Fryns JP, Gewillig M, Huylebroeck D, Peers B, Devriendt K.
Citation:
Hum Mol Genet. 2006 Nov 15;15(22):3369-77. Epub 2006 Oct 12.
Epub:
Not Epub
Abstract:
Remarkable progress has been made in understanding the molecular mechanisms underlying left-right asymmetry in vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peeters H, Voz ML, Verschueren K, De Cat B, Pendeville H, Thienpont B, Schellens A, Belmont JW, David G, Van De Ven WJ, Fryns JP, Gewillig M, Huylebroeck D, Peers B, Devriendt K.. Sesn1 is a novel gene for left-right asymmetry and mediating nodal signaling.. Hum Mol Genet. 2006 Nov 15;15(22):3369-77. Epub 2006 Oct 12..

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

Authors:
Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, Sandre-Giovannoli AD, Freije JM, Lévy N, López-Otín C
Citation:
Sci. Transl. Med. 2011;3:106ra107 doi:10.1126/scitranslmed.3002847
Epub:
Not Epub
Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is caused by a point mutation in the LMNA gene that activates a cryptic donor...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, Sandre-Giovannoli AD, Freije JM, Lévy N, López-Otín C. Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging. Sci. Transl. Med. 2011;3:106ra107 doi:10.1126/scitranslmed.3002847.

Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing

Authors:
Penn AC, Balik A, Greger IH
Citation:
Nucleic Acids Res. 2012 Nov 20. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Adenosine-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the transcriptome in...
Delivery Method:
Endo-Porter or electroporation
Organism or Cell Type:
cell culture
Citation Extract:
Penn AC, Balik A, Greger IH. Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing. Nucleic Acids Res. 2012 Nov 20. [Epub ahead of print].

Suppression and Epigenetic Regulation of MiR-9 Contributes to Ethanol Teratology: Evidence from Zebrafish and Murine Fetal Neural Stem Cell Models

Authors:
Pappalardo-Carter DL, Balaraman S, Sathyan P, Carter ES, Chen WJ, Miranda RC
Citation:
Alcohol Clin Exp Res. 2013 Jun 25. doi: 10.1111/acer.12139. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Fetal alcohol exposure produces multiorgan defects, making it difficult to identify underlying etiological...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pappalardo-Carter DL, Balaraman S, Sathyan P, Carter ES, Chen WJ, Miranda RC. Suppression and Epigenetic Regulation of MiR-9 Contributes to Ethanol Teratology: Evidence from Zebrafish and Murine Fetal Neural Stem Cell Models. Alcohol Clin Exp Res. 2013 Jun 25. doi: 10.1111/acer.12139. [Epub ahead of print].

Synthesis of 5-alkynylated uracil-morpholino monomers using Sonogashira coupling

Authors:
Paul S, Nandi B, Pattanayak S, Sinha S
Citation:
Tetrahed Lett. 2012;53(32):4179-83. doi:10.1016/j.tetlet.2012.05.141
Epub:
Not Epub
Abstract:
Sonogashira coupling of 5-iodo uracil–morpholino monomer with different terminal alkynes has been achieved for first time in...
Citation Extract:
Paul S, Nandi B, Pattanayak S, Sinha S. Synthesis of 5-alkynylated uracil-morpholino monomers using Sonogashira coupling. Tetrahed Lett. 2012;53(32):4179-83. doi:10.1016/j.tetlet.2012.05.141.

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