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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Potential role of bone morphogenetic protein-15 in zebrafish follicle development and oocyte maturation

Authors:
Peng C, Clelland E, Tan Q
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2008 Oct 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP)-15 is a member of the transforming growth factor beta (TGF-beta) superfamily and is closely...
Organism or Cell Type:
zebrafish
Citation Extract:
Peng C, Clelland E, Tan Q. Potential role of bone morphogenetic protein-15 in zebrafish follicle development and oocyte maturation. Comp Biochem Physiol A Mol Integr Physiol. 2008 Oct 12. [Epub ahead of print].

Protein kinase Cgamma is a signaling molecule required for the developmental speeding of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor kinetics

Authors:
Patten SA, Roy B, Cunningham ME, Stafford JL, Ali DW
Citation:
Eur J Neurosci. 2010 May;31(9):1561-73
Epub:
Not Epub
Abstract:
A key step in the maturation of glutamate synapses is the developmental speeding of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patten SA, Roy B, Cunningham ME, Stafford JL, Ali DW. Protein kinase Cgamma is a signaling molecule required for the developmental speeding of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor kinetics. Eur J Neurosci. 2010 May;31(9):1561-73.

Pseudoexon exclusion by antisense therapy in methylmalonic aciduria (MMAuria)

Authors:
Pérez B, Rincón A, Jorge-Finnigan A, Richard E, Merinero B, Ugarte M, Desviat LR
Citation:
Hum Mutat. 2009 Dec;30(12):1676-82
Epub:
Not Epub
Abstract:
Development of pseudoexon exclusion therapies by antisense modification of pre-mRNA splicing represents a type of personalized...
Delivery Method:
Vivo-Morpholinos and seperately Endo-Porter & bare Morpholinos
Organism or Cell Type:
cell culture: human patient primary fibroblasts
Citation Extract:
Pérez B, Rincón A, Jorge-Finnigan A, Richard E, Merinero B, Ugarte M, Desviat LR. Pseudoexon exclusion by antisense therapy in methylmalonic aciduria (MMAuria). Hum Mutat. 2009 Dec;30(12):1676-82.

PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

Authors:
Peradziryi H, Kaplan NA, Podleschny M, Liu X, Wehner P, Borchers A, Tolwinski NS
Citation:
EMBO J. 2011 Jul 19;30(18):3729-40. doi: 10.1038/emboj.2011.236
Epub:
Not Epub
Abstract:
Wnt signalling is an evolutionarily conserved pathway that directs cell-fate determination and morphogenesis during metazoan...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Peradziryi H, Kaplan NA, Podleschny M, Liu X, Wehner P, Borchers A, Tolwinski NS. PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling. EMBO J. 2011 Jul 19;30(18):3729-40. doi: 10.1038/emboj.2011.236.

Pur alpha and Sp8 as opposing regulators of neural gata2 expression

Authors:
Penberthy WT, Zhao C, Zhang Y, Jessen JR, Yang Z, Bricaud O, Collazo A, Meng A, Lin S
Citation:
Dev Biol. 2004 Nov 1;275(1):225-34
Epub:
Not Epub
Abstract:
Gata2 is an essential hematopoietic transcriptional factor that is also expressed prominently in the nervous system. The early...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Penberthy WT, Zhao C, Zhang Y, Jessen JR, Yang Z, Bricaud O, Collazo A, Meng A, Lin S. Pur alpha and Sp8 as opposing regulators of neural gata2 expression. Dev Biol. 2004 Nov 1;275(1):225-34.

Radixin is a constituent of stereocilia in hair cells

Authors:
Pataky F, Pironkova R, Hudspeth AJ
Citation:
Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2601-6
Epub:
Not Epub
Abstract:
Proteins of the ezrin-radixin-moesin family are ubiquitous constituents of the submembrane cortex, especially in epithelial...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pataky F, Pironkova R, Hudspeth AJ. Radixin is a constituent of stereocilia in hair cells. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2601-6.

Real-Time Whole-Body Visualization of Chikungunya Virus Infection and Host Interferon Response in Zebrafish

Authors:
Palha N, Guivel-Benhassine F, Briolat V, Lutfalla G, Sourisseau M, Ellett F, Wang C-H, Lieschke GJ, Herbomel P, Schwartz O, Levraud J-P
Citation:
PLoS Pathog. 2013;9(9):e1003619. doi:10.1371/journal.ppat.1003619
Epub:
Not Epub
Abstract:
Chikungunya Virus (CHIKV), a re-emerging arbovirus that may cause severe disease, constitutes an important public health...
Link:
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003619
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Palha N, Guivel-Benhassine F, Briolat V, Lutfalla G, Sourisseau M, Ellett F, Wang C-H, Lieschke GJ, Herbomel P, Schwartz O, Levraud J-P. Real-Time Whole-Body Visualization of Chikungunya Virus Infection and Host Interferon Response in Zebrafish. PLoS Pathog. 2013;9(9):e1003619. doi:10.1371/journal.ppat.1003619.

Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme Cyp11a2

Authors:
Parajes S, Griffin A, Taylor AE, Rose IT, Miguel-Escalada I, Hadzhiev Y, Arlt W, Shackleton C, Müller F, Krone N
Citation:
Endocrinology. 2013 May 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Zebrafish are emerging as a model to study steroid hormone action and associated disease. However, steroidogenesis in zebrafish...
Organism or Cell Type:
zebrafish
Citation Extract:
Parajes S, Griffin A, Taylor AE, Rose IT, Miguel-Escalada I, Hadzhiev Y, Arlt W, Shackleton C, Müller F, Krone N. Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme Cyp11a2. Endocrinology. 2013 May 13. [Epub ahead of print].

Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis

Authors:
Panchal RG, Ulrich RL, Bradfute SB, Lane D, Ruthel G, Kenny TA, Iversen PL, Anderson AO, Gussio R, Raschke WC, Bavari S
Citation:
J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6.
Epub:
Not Epub
Abstract:
The modulation of cellular processes by small molecule inhibitors, gene inactivation or targeted knock-down strategies combined...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice and cell culture: macrophage J774A.1 cells
Citation Extract:
Panchal RG, Ulrich RL, Bradfute SB, Lane D, Ruthel G, Kenny TA, Iversen PL, Anderson AO, Gussio R, Raschke WC, Bavari S. Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis. J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6..

Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2

Authors:
Pannicke U, Hönig M, Hess I, Friesen C, Holzmann K, Rump EM, Barth TF, Rojewski MT, Schulz A, Boehm T, Friedrich W, Schwarz K
Citation:
Nat Genet. 2009 Jan;41(1):101-5. Epub 2008 Nov 30
Epub:
Not Epub
Abstract:
Human severe combined immunodeficiencies (SCID) are phenotypically and genotypically heterogeneous diseases. Reticular...
Organism or Cell Type:
zebrafish
Citation Extract:
Pannicke U, Hönig M, Hess I, Friesen C, Holzmann K, Rump EM, Barth TF, Rojewski MT, Schulz A, Boehm T, Friedrich W, Schwarz K. Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. Nat Genet. 2009 Jan;41(1):101-5. Epub 2008 Nov 30.

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