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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death
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Citation:
Antivir Ther. 2009;14(7):899-909 Epub:
Not Epub Abstract:
BACKGROUND: Porcine reproductive and respiratory syndrome (PRRS) causes extensive economic losses in the swine industry.... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: porcine pulmonary alveolar macrophages Citation Extract: Patel D, Stein DA, Zhang YJ. Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death. Antivir Ther. 2009;14(7):899-909. |
Morpholino-Mediated Increase in Soluble Flt-1 Expression Results in Decreased Ocular and Tumor Neovascularization
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Citation:
PLoS ONE. 2012;7(3):e33576. doi:10.1371/journal.pone.0033576 Epub:
Not Epub Abstract:
Background Angiogenesis is a key process in several ocular disorders and cancers. Soluble Flt-1 is an alternatively spliced... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice, nude Citation Extract: Owen LA, Uehara H, Cahoon J, Huang W, Simonis J, Ambati BK. Morpholino-Mediated Increase in Soluble Flt-1 Expression Results in Decreased Ocular and Tumor Neovascularization. PLoS ONE. 2012;7(3):e33576. doi:10.1371/journal.pone.0033576. |
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
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Citation:
Nat Genet. 2003 Aug;34(4):413-20 Epub:
Not Epub Abstract:
Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease, leads to chronic renal failure in children. The genes... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Otto EA, Schermer B, Obara T, O'Toole JF, Hiller KS, Mueller AM, Ruf RG, Hoefele J, Beekmann F, Landau D, Foreman JW, Goodship JA, Strachan T, Kispert A, Wolf MT, Gagnadoux MF, Nivet H, Antignac C, Walz G, Drummond IA, Benzing T, Hildebrandt F. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat Genet. 2003 Aug;34(4):413-20. |
Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development
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Citation:
Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10202-7. Epub 2011 Jun 1 Epub:
Not Epub Abstract:
What makes embryogenesis a robust and canalized process is an important question in developmental biology. A bone morphogenetic... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Paulsen M, Legewie S, Eils R, Karaulanov E, Niehrs C. Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10202-7. Epub 2011 Jun 1. |
Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish
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Citation:
Development. 2011;138:4499-509; doi:10.1242/dev.067454 Epub:
Not Epub Abstract:
The extracellular matrix is crucial for organogenesis. It is a complex and dynamic component that regulates cell behavior by... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Patra C, Diehl F, Ferrazzi F, van Amerongen MJ, Novoyatleva T, Schaefer L, Mühlfeld C, Jungblut J, Engel FB. Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish. Development. 2011;138:4499-509; doi:10.1242/dev.067454. |
Neural crest specification by noncanonical Wnt signaling and PAR-1
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Citation:
Development. 2011;138:5441-50. doi:10.1242/dev.067280 Epub:
Not Epub Abstract:
Neural crest (NC) cells are multipotent progenitors that form at the neural plate border, undergo epithelial-mesenchymal... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Ossipova O, Sokol SY. Neural crest specification by noncanonical Wnt signaling and PAR-1. Development. 2011;138:5441-50. doi:10.1242/dev.067280 . |
New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia
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Citation:
Development, Mar 2007; 134: 921 - 931. Epub:
Not Epub Abstract:
Human ARHGEF11, a PDZ-domain-containing Rho guanine nucleotide exchange factor (RhoGEF), has been studied primarily in tissue... Organism or Cell Type:
zebrafish Citation Extract: Panizzi JR, Jessen JR, Drummond IA, Solnica-Krezel L. New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia. Development, Mar 2007; 134: 921 - 931.. |
NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells
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Citation:
EMBO J. 2012;[Epub ahead of print] doi:10.1038/emboj.2012.46 Epub:
Not Epub Abstract:
Nemo-like kinase (NLK/Nlk) is an evolutionarily conserved protein kinase involved in Wnt/β-catenin signalling. However, the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ota S, Ishitani S, Shimizu N, Matsumoto K, Itoh M, Ishitani T. NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells. EMBO J. 2012;[Epub ahead of print] doi:10.1038/emboj.2012.46. |
Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish
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Citation:
PLoS One. 2013 Jun 28;8(6):e68021. doi: 10.1371/journal.pone.0068021. Print 2013. Epub:
Not Epub Abstract:
BACKGROUND: Accurate regulation of Notch signalling is central for developmental processes in a variety of tissues, but its... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pascoal S, Esteves de Lima J, Leslie JD, Hughes SM, Saúde L. Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish. PLoS One. 2013 Jun 28;8(6):e68021. doi: 10.1371/journal.pone.0068021. Print 2013.. |
Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen
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Citation:
Circulation. 2011 Jan 4;123(1):23-30. Epub 2010 Nov 15. Epub:
Not Epub Abstract:
Background- Genetic long QT (LQT) syndrome is a life-threatening disorder caused by mutations that result in prolongation of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ. Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen. Circulation. 2011 Jan 4;123(1):23-30. Epub 2010 Nov 15.. |