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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes

Authors:
Pearl EJ, Jarikji Z, Horb ME
Citation:
Dev Biol. 2011 Mar 1;351(1):135-45. Epub 2011 Jan 4
Epub:
Not Epub
Abstract:
Mutations in rfx6 were recently associated with Mitchell-Riley syndrome, which involves neonatal diabetes, and other digestive...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pearl EJ, Jarikji Z, Horb ME. Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. Dev Biol. 2011 Mar 1;351(1):135-45. Epub 2011 Jan 4.

Functional conservation of erythropoietin signaling in zebrafish

Authors:
Paffett-Lugassy N, Hsia N, Fraenkel PG, Paw B, Leschinsky I, Barut B, Bahary N, Caro J, Handin R, Zon LI
Citation:
Blood. 2007 Oct 1;110(7):2718-26. Epub 2007 Jun 19
Epub:
Not Epub
Abstract:
Erythropoietin (Epo) and its cognate receptor (EpoR) are required for maintaining adequate levels of circulating erythrocytes...
Organism or Cell Type:
zebrafish
Citation Extract:
Paffett-Lugassy N, Hsia N, Fraenkel PG, Paw B, Leschinsky I, Barut B, Bahary N, Caro J, Handin R, Zon LI. Functional conservation of erythropoietin signaling in zebrafish. Blood. 2007 Oct 1;110(7):2718-26. Epub 2007 Jun 19.

Functional Knowledge Transfer for High-accuracy Prediction of Under-studied Biological Processes

Authors:
Park CY, Wong AK, Greene CS, Rowland J, Guan Y, Bongo LA, Burdine RD, Troyanskaya OG
Citation:
PLoS Comput Biol. 2013;9(3):e1002957. doi:10.1371/journal.pcbi.1002957
Epub:
Not Epub
Abstract:
A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics techniques (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Park CY, Wong AK, Greene CS, Rowland J, Guan Y, Bongo LA, Burdine RD, Troyanskaya OG. Functional Knowledge Transfer for High-accuracy Prediction of Under-studied Biological Processes. PLoS Comput Biol. 2013;9(3):e1002957. doi:10.1371/journal.pcbi.1002957.

Genetic modeling of Li-Fraumeni syndrome in zebrafish

Authors:
Parant JM, George SA, Holden JA, Yost HJ
Citation:
Dis Model Mech. 2010 Jan-Feb;3(1-2):45-56
Epub:
Not Epub
Abstract:
Li-Fraumeni syndrome (LFS) is a highly penetrant, autosomal dominant, human familial cancer predisposition. Although a key role...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Parant JM, George SA, Holden JA, Yost HJ. Genetic modeling of Li-Fraumeni syndrome in zebrafish. Dis Model Mech. 2010 Jan-Feb;3(1-2):45-56.

Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function

Authors:
Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, et al
Citation:
PLoS Genet. 2012;8(3):e1002584. doi:10.1371/journal.pgen.1002584
Epub:
Not Epub
Abstract:
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, et al. Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function. PLoS Genet. 2012;8(3):e1002584. doi:10.1371/journal.pgen.1002584.

Germ cells in the crustacean Parhyale hawaiensis depend on Vasa protein for their maintenance but not for their formation

Authors:
Ozhan-Kizil G, Havemann J, Gerberding M
Citation:
Dev Biol. 2009 Mar 1;327(1):230-9. Epub 2008 Nov 5
Epub:
Not Epub
Abstract:
Germ cells are a population of cells that do not differentiate to form somatic tissue but form the egg and sperm that ensure...
Organism or Cell Type:
Parhyale hawaiensis
Citation Extract:
Ozhan-Kizil G, Havemann J, Gerberding M. Germ cells in the crustacean Parhyale hawaiensis depend on Vasa protein for their maintenance but not for their formation. Dev Biol. 2009 Mar 1;327(1):230-9. Epub 2008 Nov 5.

GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness

Authors:
Peachey NS, Ray TA, Florijn R, Rowe LB, Sjoerdsma T, Contreras-Alcantara S, Baba K, Tosini G, Pozdeyev N, Iuvone PM, Bojang P Jr, Pearring JN, Simonsz HJ, van Genderen M, Birch DG, Traboulsi EI, Dorfman A, Lopez I, Ren H, Goldberg AF, Nishina PM, Lachapelle P, McCall MA, Koenekoop RK, Bergen AA, Kamermans M, Gregg RG.
Citation:
Am J Hum Genet. 2012 Feb 10;90(2):331-9
Epub:
Not Epub
Abstract:
Complete congenital stationary night blindness (cCSNB) is a clinically and genetically heterogeneous group of retinal disorders...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peachey NS, Ray TA, Florijn R, Rowe LB, Sjoerdsma T, Contreras-Alcantara S, Baba K, Tosini G, Pozdeyev N, Iuvone PM, Bojang P Jr, Pearring JN, Simonsz HJ, van Genderen M, Birch DG, Traboulsi EI, Dorfman A, Lopez I, Ren H, Goldberg AF, Nishina PM, Lachapelle P, McCall MA, Koenekoop RK, Bergen AA, Kamermans M, Gregg RG.. GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet. 2012 Feb 10;90(2):331-9.

Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation

Authors:
Passeri MJ, Cinaroglu A, Gao C, Sadler KC
Citation:
Hepatology. 2009 Feb;49(2):443-52.
Epub:
Not Epub
Abstract:
Steatosis is the most common consequence of acute alcohol abuse and may predispose to more severe hepatic disease. Increased...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Passeri MJ, Cinaroglu A, Gao C, Sadler KC. Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation. Hepatology. 2009 Feb;49(2):443-52..

Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus

Authors:
Park BY, Saint-Jeannet JP
Citation:
Dev Biol. 2008 Dec 1;324(1):108-21. Epub 2008 Sep 19
Epub:
Not Epub
Abstract:
Induction of the otic placode, the rudiment of the inner ear, is believed to depend on signals derived from surrounding tissues...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park BY, Saint-Jeannet JP. Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus. Dev Biol. 2008 Dec 1;324(1):108-21. Epub 2008 Sep 19.

Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia

Authors:
Pei W, Feldman B
Citation:
Dev Biol. 2009 Feb 1;326(1):201-11. Epub 2008 Nov 19
Epub:
Not Epub
Abstract:
Loss of the zebrafish Nodal-related protein Squint causes a spectrum of phenotypes including cyclopia and midline bifurcations...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pei W, Feldman B. Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia. Dev Biol. 2009 Feb 1;326(1):201-11. Epub 2008 Nov 19.

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