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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

Authors:
Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J, Lopez I, Washburn J, Macdonald J, Hu J, Yamashita Y, Maher ER, Guay-Woodford LM, Neumann HP, Obermüller N, Koenekoop RK, Bergmann C, Bei X, Lewis RA, Katsanis N, Lopes V, Williams DS, Lyons RH, Dang CV, Brito DA, Dias MB, Zhang X, Cavalcoli JD, Nürnberg G, Nürnberg P, Pierce EA, Jackson PK, Antignac C, Saunier S, Roepman R, Dollfus H, Khanna H, Hildebrandt F.
Citation:
Nat Genet. 2010 Oct;42(10):840-50. Epub 2010 Sep 12.
Epub:
Not Epub
Abstract:
Nephronophthisis-related ciliopathies (NPHP-RC) are recessive disorders that feature dysplasia or degeneration occurring...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J, Lopez I, Washburn J, Macdonald J, Hu J, Yamashita Y, Maher ER, Guay-Woodford LM, Neumann HP, Obermüller N, Koenekoop RK, Bergmann C, Bei X, Lewis RA, Katsanis N, Lopes V, Williams DS, Lyons RH, Dang CV, Brito DA, Dias MB, Zhang X, Cavalcoli JD, Nürnberg G, Nürnberg P, Pierce EA, Jackson PK, Antignac C, Saunier S, Roepman R, Dollfus H, Khanna H, Hildebrandt F. . Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet. 2010 Oct;42(10):840-50. Epub 2010 Sep 12..

Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI

Authors:
Padmanabhan A, Lee JS, Ismat FA, Lu MM, Lawson ND, Kanki JP, Look AT, Epstein JA
Citation:
Proc Natl Acad Sci U S A. 2009 Dec 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Von Recklinghausen neurofibromatosis is a common autosomal dominant genetic disorder characterized by benign and malignant...
Organism or Cell Type:
zebrafish
Citation Extract:
Padmanabhan A, Lee JS, Ismat FA, Lu MM, Lawson ND, Kanki JP, Look AT, Epstein JA. Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI. Proc Natl Acad Sci U S A. 2009 Dec 4. [Epub ahead of print].

CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms

Authors:
Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, Gupta A, Kramer-Zucker A, Olale F, Burdine RD, Schier AF, O'Callaghan C, Chung EM, Reinhardt R, Mitchison HM, King SM, Omran H, Drummond IA
Citation:
Nat Genet. 2012 May 13. doi: 10.1038/ng.2277. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cilia are essential for fertilization, respiratory clearance, cerebrospinal fluid circulation and establishing laterality....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, Gupta A, Kramer-Zucker A, Olale F, Burdine RD, Schier AF, O'Callaghan C, Chung EM, Reinhardt R, Mitchison HM, King SM, Omran H, Drummond IA. CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nat Genet. 2012 May 13. doi: 10.1038/ng.2277. [Epub ahead of print].

Cdkn1c drives muscle differentiation through a positive feedback loop with Myod

Authors:
Osborn DP, Li K, Hinits Y, Hughes SM
Citation:
Dev Biol. 2011 Feb 15;350(2):464-75. Epub 2010 Dec 11
Epub:
Not Epub
Abstract:
Differentiation often requires conversion of analogue signals to a stable binary output through positive feedback. Hedgehog (Hh...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborn DP, Li K, Hinits Y, Hughes SM. Cdkn1c drives muscle differentiation through a positive feedback loop with Myod. Dev Biol. 2011 Feb 15;350(2):464-75. Epub 2010 Dec 11.

CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis

Authors:
Pan W, Pham VN, Stratman AN, Castranova D, Kamei M, Kidd KR, Lo BD, Shaw KM, Torres-Vazquez J, Mikelis CM, Gutkind JS, Davis GE, Weinstein BM
Citation:
Blood. 2012 Jul 12;120(2):489-98. doi: 10.1182/blood-2012-02-408328. Epub 2012 May 30.
Epub:
Not Epub
Abstract:
Understanding the mechanisms that regulate angiogenesis and translating these into effective therapies are of enormous...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pan W, Pham VN, Stratman AN, Castranova D, Kamei M, Kidd KR, Lo BD, Shaw KM, Torres-Vazquez J, Mikelis CM, Gutkind JS, Davis GE, Weinstein BM. CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood. 2012 Jul 12;120(2):489-98. doi: 10.1182/blood-2012-02-408328. Epub 2012 May 30..

Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo

Authors:
Panagiotaki N, Dajas-Bailador F, Amaya E, Papalopulu N, Dorey K
Citation:
Development. 2010 Dec;137(23):4005-15
Epub:
Not Epub
Abstract:
During development, many organs, including the kidney, lung and mammary gland, need to branch in a regulated manner to be...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Panagiotaki N, Dajas-Bailador F, Amaya E, Papalopulu N, Dorey K. Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo. Development. 2010 Dec;137(23):4005-15.

Chondroitin sulfate expression is required for cardiac atrioventricular canal formation

Authors:
Peal DS, Burns CG, Macrae CA, Milan D
Citation:
Dev Dyn. 2009 Dec;238(12):3103-10
Epub:
Not Epub
Abstract:
Defects in cardiac valvulogenesis are a common cause of congenital heart disease, and the study of this process promises to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peal DS, Burns CG, Macrae CA, Milan D. Chondroitin sulfate expression is required for cardiac atrioventricular canal formation. Dev Dyn. 2009 Dec;238(12):3103-10.

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

Authors:
Park TJ, Haigo SL, Wallingford JB
Citation:
Nat Genet. 2006 Mar;38(3):303-11. Epub 2006 Feb 19
Epub:
Not Epub
Abstract:
The vertebrate planar cell polarity (PCP) pathway has previously been found to control polarized cell behaviors rather than...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Park TJ, Haigo SL, Wallingford JB. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet. 2006 Mar;38(3):303-11. Epub 2006 Feb 19.

Clinical, biochemical, and molecular studies in pyridoxine-dependent epilepsy. Antisense therapy as possible new therapeutic option

Authors:
Pérez B, Gutiérrez-Solana LG, Verdú A, Merinero B, Yuste-Checa P, Ruiz-Sala P, Calvo R, Jalan A, Marín LL, Campos O, Ruiz MA, Miguel MS, Vázquez M, Castro M, Ferrer I, Navarrete R, Desviat LR, Lapunzina P, Ugarte M, Pérez-Cerdá C
Citation:
Epilepsia. 2013 Jan 25. doi: 10.1111/epi.12083. [Epub ahead of print]
Epub:
Not Epub
Abstract:
<edited for length> PURPOSE: Pyridoxine-dependent epilepsy seizure (PDE; OMIM 266100) is a disorder associated with...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary human lymphoblasts
Citation Extract:
Pérez B, Gutiérrez-Solana LG, Verdú A, Merinero B, Yuste-Checa P, Ruiz-Sala P, Calvo R, Jalan A, Marín LL, Campos O, Ruiz MA, Miguel MS, Vázquez M, Castro M, Ferrer I, Navarrete R, Desviat LR, Lapunzina P, Ugarte M, Pérez-Cerdá C. Clinical, biochemical, and molecular studies in pyridoxine-dependent epilepsy. Antisense therapy as possible new therapeutic option. Epilepsia. 2013 Jan 25. doi: 10.1111/epi.12083. [Epub ahead of print].

Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis

Authors:
Peng Y, Yang PH, Tanner JA, Huang JD, Li M, Lee HF, Xu RH, Kung HF, Lin MC
Citation:
Biochem Biophys Res Commun. 2006 May 26;344(1):416-24. Epub 2006 Mar 24.
Epub:
Not Epub
Abstract:
We have previously shown that the Xenopus homologue of cold-inducible RNA binding protein, XCIRP-1, is required for the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Peng Y, Yang PH, Tanner JA, Huang JD, Li M, Lee HF, Xu RH, Kung HF, Lin MC. Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis. Biochem Biophys Res Commun. 2006 May 26;344(1):416-24. Epub 2006 Mar 24..

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