You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3

Authors:
Pei W, Kratz LE, Bernardini I, Sood R, Yokogawa T, Dorward H, Ciccone C, Kelley RI, Anikster Y, Burgess HA, Huizing M, Feldman B
Citation:
Development. 2010 Aug 1;137(15):2587-96
Epub:
Not Epub
Abstract:
Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pei W, Kratz LE, Bernardini I, Sood R, Yokogawa T, Dorward H, Ciccone C, Kelley RI, Anikster Y, Burgess HA, Huizing M, Feldman B. A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3. Development. 2010 Aug 1;137(15):2587-96.

A Model of Glucose-6-Phosphate Dehydrogenase Deficiency in the Zebrafish

Authors:
Patrinostro X, Carter ML, Kramer AC, Lund TC
Citation:
Exp Hematol. 2013 Apr 16. doi:pii: S0301-472X(13)00124-0. 10.1016/j.exphem.2013.04.002. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common genetic defect and enzymopathy worldwide, affecting...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patrinostro X, Carter ML, Kramer AC, Lund TC. A Model of Glucose-6-Phosphate Dehydrogenase Deficiency in the Zebrafish. Exp Hematol. 2013 Apr 16. doi:pii: S0301-472X(13)00124-0. 10.1016/j.exphem.2013.04.002. [Epub ahead of print].

A positive role for the Ku complex in DNA replication following strand break damage in mammals

Authors:
Park SJ, Ciccone SL, Freie B, Kurimasa A, Chen DJ, Li GC, Clapp DW, Lee SH
Citation:
J Biol Chem. 2003 Nov 15 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ku70/Ku80 complex is the regulatory subunits of DNA-dependent protein kinase (DNA-PK) and plays an essential role in double...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Park SJ, Ciccone SL, Freie B, Kurimasa A, Chen DJ, Li GC, Clapp DW, Lee SH. A positive role for the Ku complex in DNA replication following strand break damage in mammals. J Biol Chem. 2003 Nov 15 [Epub ahead of print].

A simple method for delivering morpholino antisense oligos into the cytoplasm of cells

Authors:
Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J
Citation:
Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75
Epub:
Not Epub
Abstract:
We report a simple and effective means for delivering Morpholino antisense oligos into the cytosol of cultured anchorage-...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: Hela and rat FT02B liver cells
Citation Extract:
Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J. A simple method for delivering morpholino antisense oligos into the cytoplasm of cells. Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75.

A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development

Authors:
Paige SL, Thomas S, Stoick-Cooper CL, Wang H, Maves L, Sandstrom S, Pabon L, Reinecke H, Pratt G, Keller G, Moon RT, Stamatoyannopoulos J, Murry CE
Citation:
Cell. 2012;[Epub ahead of print] doi:10.1016/j.cell.2012.08.027
Epub:
Not Epub
Abstract:
Directed differentiation of human embryonic stem cells (ESCs) into cardiovascular cells provides a model for studying molecular...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paige SL, Thomas S, Stoick-Cooper CL, Wang H, Maves L, Sandstrom S, Pabon L, Reinecke H, Pratt G, Keller G, Moon RT, Stamatoyannopoulos J, Murry CE. A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development. Cell. 2012;[Epub ahead of print] doi:10.1016/j.cell.2012.08.027.

An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins

Authors:
Paredez AR, Assaf ZJ, Sept D, Timofejeva L, Dawson SC, Wang CJ, Cande WZ
Citation:
Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6151-6. Epub 2011 Mar 28.
Epub:
Not Epub
Abstract:
Giardia intestinalis, a human intestinal parasite and member of what is perhaps the earliest-diverging eukaryotic lineage,...
Delivery Method:
Electroporation
Organism or Cell Type:
Giardia intestinalis
Citation Extract:
Paredez AR, Assaf ZJ, Sept D, Timofejeva L, Dawson SC, Wang CJ, Cande WZ. An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6151-6. Epub 2011 Mar 28..

An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells

Authors:
Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB
Citation:
J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07
Epub:
Not Epub
Abstract:
1-cys peroxiredoxin (1-cysPrx), a member of the peroxiredoxin superfamily, reduces phospholipid hydroperoxides as well as...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: L2 cells
Citation Extract:
Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB. An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells. J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07.

An early requirement for maternal FoxH1 during zebrafish gastrulation

Authors:
Pei W, Noushmehr H, Costa J, Ouspenskaia MV, Elkahloun AG, Feldman B
Citation:
Dev Biol. 2007 Oct 1;310(1):10-22. Epub 2007 Jul 19.
Epub:
Not Epub
Abstract:
The Forkhead Box H1 (FoxH1) protein is a co-transcription factor recruited by phosphorylated Smad2 downstream of several...
Organism or Cell Type:
zebrafish
Citation Extract:
Pei W, Noushmehr H, Costa J, Ouspenskaia MV, Elkahloun AG, Feldman B. An early requirement for maternal FoxH1 during zebrafish gastrulation. Dev Biol. 2007 Oct 1;310(1):10-22. Epub 2007 Jul 19..

Basal body stability and ciliogenesis requires the conserved component Poc1

Authors:
Pearson CG, Osborn DP, Giddings TH Jr, Beales PL, Winey M
Citation:
J Cell Biol. 2009 Dec 14;187(6):905-20
Epub:
Not Epub
Abstract:
Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is initiated by an assembly...
Organism or Cell Type:
zebrafish
Citation Extract:
Pearson CG, Osborn DP, Giddings TH Jr, Beales PL, Winey M. Basal body stability and ciliogenesis requires the conserved component Poc1. J Cell Biol. 2009 Dec 14;187(6):905-20.

Bi-polarized translation of ascidian maternal mRNA determinant pem-1 associated with regulators of the translation machinery on the cortical endoplasmic reticulum (cER)

Authors:
Paix A, Le Nguyen PN, Sardet C
Citation:
Dev Biol. 2011 Jun 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Polarized cortical mRNA determinants such as maternal macho-1 and pem-1 in ascidians, like budding yeast mating factor ASH1...
Delivery Method:
Microinjection
Citation Extract:
Paix A, Le Nguyen PN, Sardet C. Bi-polarized translation of ascidian maternal mRNA determinant pem-1 associated with regulators of the translation machinery on the cortical endoplasmic reticulum (cER). Dev Biol. 2011 Jun 23. [Epub ahead of print].

Pages