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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori

Authors:
Nossa CW, Jain P, Tamilselvam B, Gupta VR, Chen LF, Schreiber V, Desnoyers S, Blanke SR
Citation:
Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19998-20003. Epub 2009 Nov 6
Epub:
Not Epub
Abstract:
Modification of eukaryotic proteins is a powerful strategy used by pathogenic bacteria to modulate host cells during infection...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: AGS cells infected with H. pylori 26695
Citation Extract:
Nossa CW, Jain P, Tamilselvam B, Gupta VR, Chen LF, Schreiber V, Desnoyers S, Blanke SR. Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19998-20003. Epub 2009 Nov 6.

Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy

Authors:
Ohashi S, Abe H, Takahashi T, Yamamoto Y, Takeuchi M, Arai H, Nagata K, Kita T, Okamoto H, Yamamoto H, Doi T
Citation:
J Biol Chem. 2004 May 7;279(19):19816-23. Epub 2004 Mar 05.
Epub:
Not Epub
Abstract:
Advanced glycation end products (AGEs) appear to contribute to the diabetic complications. This study reports the inhibitory...
Organism or Cell Type:
cell culture: mouse glomerular mesangial cells
Citation Extract:
Ohashi S, Abe H, Takahashi T, Yamamoto Y, Takeuchi M, Arai H, Nagata K, Kita T, Okamoto H, Yamamoto H, Doi T. Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy. J Biol Chem. 2004 May 7;279(19):19816-23. Epub 2004 Mar 05..

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Authors:
Nuzzo F, Radu C, Baralle M, Spiezia L, Hackeng TM, Simioni P, Castoldi E
Citation:
Blood. 2013 Oct 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense molecules are emerging as a powerful tool to correct splicing defects. Recently, we identified a homozygous deep-...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary megakaryocytes
Citation Extract:
Nuzzo F, Radu C, Baralle M, Spiezia L, Hackeng TM, Simioni P, Castoldi E. Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation. Blood. 2013 Oct 1. [Epub ahead of print].

B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo

Authors:
Okuda Y, Ogura E, Kondoh H, Kamachi Y
Citation:
PLoS Genet. 2010 May 6;6(5):e1000936
Epub:
Not Epub
Abstract:
The B1 SOX transcription factors SOX1/2/3/19 have been implicated in various processes of early embryogenesis. However, their...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Okuda Y, Ogura E, Kondoh H, Kamachi Y. B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. PLoS Genet. 2010 May 6;6(5):e1000936.

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation

Authors:
Oliveira MI, Gonçalves CM, Pinto M, Fabre S, Santos AM, Lee SF, Castro MAA, Nunes RJ, Barbosa RR, Parnes JR, Yu C, Davis SJ, Moreira A, Bismuth G, Carmo AM
Citation:
Eur. J. Immunol. 2012 Jan;42(1):195-205. doi: 10.1002/eji.201040528. Epub 2011 Nov 28.
Epub:
Not Epub
Abstract:
The T lineage glycoprotein CD6 is generally considered to be a co-activator of T-cell activation. Here we demonstrate that CD6...
Delivery Method:
Electroporation (Amaxa)
Organism or Cell Type:
cell culture: human T lymphocytes
Citation Extract:
Oliveira MI, Gonçalves CM, Pinto M, Fabre S, Santos AM, Lee SF, Castro MAA, Nunes RJ, Barbosa RR, Parnes JR, Yu C, Davis SJ, Moreira A, Bismuth G, Carmo AM. CD6 attenuates early and late signaling events, setting thresholds for T-cell activation. Eur. J. Immunol. 2012 Jan;42(1):195-205. doi: 10.1002/eji.201040528. Epub 2011 Nov 28..

Chordin is required for the spemann organizer transplantation phenomenon in Xenopus embryos

Authors:
Oelgeschlager M, Kuroda H, Reversade B, De Robertis EM
Citation:
Dev Cell. 2003 Feb;4(2):219-30
Epub:
Not Epub
Abstract:
We analyzed the Chordin requirement in Xenopus development. Targeting of both chordin Xenopus laevis pseudoalleles with...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Oelgeschlager M, Kuroda H, Reversade B, De Robertis EM. Chordin is required for the spemann organizer transplantation phenomenon in Xenopus embryos. Dev Cell. 2003 Feb;4(2):219-30.

Comparison of morpholino based translational inhibition during the development of Xenopus laevis and Xenopus tropicalis

Authors:
Nutt SL, Bronchain OJ, Hartley KO, Amaya E
Citation:
Genesis. 2001 Jul;30(3):110-3
Epub:
Not Epub
Abstract:
Morpholino (MO) based inhibition of translational initiation represents an attractive methodology to eliminate gene function...
Delivery Method:
Microinjection
Organism or Cell Type:
X.laevis & X.tropicalis
Citation Extract:
Nutt SL, Bronchain OJ, Hartley KO, Amaya E. Comparison of morpholino based translational inhibition during the development of Xenopus laevis and Xenopus tropicalis. Genesis. 2001 Jul;30(3):110-3.

Cooperative function of deltaC and her7 in anterior segment formation

Authors:
Oates AC, Mueller C, Ho RK
Citation:
Dev Biol. 2005 Apr 1;280(1):133-49
Epub:
Not Epub
Abstract:
Segmentation of paraxial mesoderm in vertebrates is regulated by a genetic oscillator that manifests as a series of wavelike or...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oates AC, Mueller C, Ho RK. Cooperative function of deltaC and her7 in anterior segment formation. Dev Biol. 2005 Apr 1;280(1):133-49.

Coordinate development of skin cells and cutaneous sensory axons in zebrafish

Authors:
O'Brien GS, Rieger S, Wang F, Smolen GA, Gonzalez RE, Buchanan J, Sagasti A
Citation:
J Comp Neurol. 2011 Oct 20. doi: 10.1002/cne.22791. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Peripheral sensory axons innervate the epidermis early in embryogenesis to detect touch stimuli. To characterize the time...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
O'Brien GS, Rieger S, Wang F, Smolen GA, Gonzalez RE, Buchanan J, Sagasti A. Coordinate development of skin cells and cutaneous sensory axons in zebrafish. J Comp Neurol. 2011 Oct 20. doi: 10.1002/cne.22791. [Epub ahead of print].

Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells

Authors:
Okuda S, Tsutsui H, Shiina K, Sprunck S, Takeuchi H, Yui R, Kasahara RD, Hamamura Y, Mizukami A, Susaki D, Kawano N, Sakakibara T, Namiki S, Itoh K, Otsuka K, Matsuzaki M, Nozaki H, Kuroiwa T, Nakano A, Kanaoka MM, Dresselhaus T, Sasaki N, Higashiyama T
Citation:
Nature. 2009 Mar 19;458(7236):357-61
Epub:
Not Epub
Abstract:
For more than 140 years, pollen tube guidance in flowering plants has been thought to be mediated by chemoattractants derived...
Link:
https://www.nature.com/articles/nature07882
Organism or Cell Type:
Torenia fournieri
Citation Extract:
Okuda S, Tsutsui H, Shiina K, Sprunck S, Takeuchi H, Yui R, Kasahara RD, Hamamura Y, Mizukami A, Susaki D, Kawano N, Sakakibara T, Namiki S, Itoh K, Otsuka K, Matsuzaki M, Nozaki H, Kuroiwa T, Nakano A, Kanaoka MM, Dresselhaus T, Sasaki N, Higashiyama T. Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells. Nature. 2009 Mar 19;458(7236):357-61.

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