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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

Authors:
O'Connor MN, Salles II, Cvejic A, Watkins NA, Walker A, Garner SF, Jones CI, Macaulay IC, Steward M, Zwaginga JJ, Bray SL, Dudbridge F, de Bono B, Goodall AH, Deckmyn H, Stemple DL, Ouwehand WH
Citation:
Blood. 2008 Dec 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In this study we demonstrate the suitability of the vertebrate Danio rerio (zebrafish) for functional screening of novel...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
O'Connor MN, Salles II, Cvejic A, Watkins NA, Walker A, Garner SF, Jones CI, Macaulay IC, Steward M, Zwaginga JJ, Bray SL, Dudbridge F, de Bono B, Goodall AH, Deckmyn H, Stemple DL, Ouwehand WH. Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins. Blood. 2008 Dec 24. [Epub ahead of print].

Genome-wide Studies of Copy Number Variation and Exome Sequencing Identify Rare Variants in BAG3 as a Cause of Dilated Cardiomyopathy

Authors:
Norton N, Li D, Rieder MJ, Siegfried JD, Rampersaud E, Züchner S, Mangos S, Gonzalez-Quintana J, Wang L, McGee S, Reiser J, Martin E, Nickerson DA, Hershberger RE
Citation:
The American Journal of Human Genetics. 2011 Feb 24 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Dilated cardiomyopathy commonly causes heart failure and is the most frequent precipitating cause of heart transplantation....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Norton N, Li D, Rieder MJ, Siegfried JD, Rampersaud E, Züchner S, Mangos S, Gonzalez-Quintana J, Wang L, McGee S, Reiser J, Martin E, Nickerson DA, Hershberger RE. Genome-wide Studies of Copy Number Variation and Exome Sequencing Identify Rare Variants in BAG3 as a Cause of Dilated Cardiomyopathy. The American Journal of Human Genetics. 2011 Feb 24 [Epub ahead of print].

Global regulatory logic for specification of an embryonic cell lineage

Authors:
Oliveri P, Tu Q, Davidson EH
Citation:
Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):5955-62. Epub 2008 Apr 14.
Epub:
Not Epub
Abstract:
Explanation of a process of development must ultimately be couched in the terms of the genomic regulatory code. Specification...
Organism or Cell Type:
sea urchin
Citation Extract:
Oliveri P, Tu Q, Davidson EH. Global regulatory logic for specification of an embryonic cell lineage. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):5955-62. Epub 2008 Apr 14..

Growth differentiation factor 9 promotes rat preantral follicle growth by up-regulating follicular androgen biosynthesis

Authors:
Orisaka M, Jiang JY, Orisaka S, Kotsuji F, Tsang BK
Citation:
Endocrinology. 2009 Jun;150(6):2740-8. Epub 2009 Feb 12
Epub:
Not Epub
Abstract:
The transition from preantral to early antral stage is the penultimate stage of ovarian follicular development in terms of...
Organism or Cell Type:
Rat
Citation Extract:
Orisaka M, Jiang JY, Orisaka S, Kotsuji F, Tsang BK. Growth differentiation factor 9 promotes rat preantral follicle growth by up-regulating follicular androgen biosynthesis. Endocrinology. 2009 Jun;150(6):2740-8. Epub 2009 Feb 12.

Growth Differentiation Factor-9 Is Anti-Apoptotic during Follicular Development from Preantral to Early Antral Stage

Authors:
Orisaka M, Orisaka S, Jiang JY, Craig J, Wang Y, Kotsuji F, Tsang BK
Citation:
Mol Endocrinol. 2006 Oct;20(10):2456-68. Epub 2006 Jun 1.
Epub:
Not Epub
Abstract:
Ovarian follicular atresia represents a selection process that ensures the release of only healthy and viable oocytes during...
Delivery Method:
Microinjection
Organism or Cell Type:
Sprague Dawley rats follicles
Citation Extract:
Orisaka M, Orisaka S, Jiang JY, Craig J, Wang Y, Kotsuji F, Tsang BK. Growth Differentiation Factor-9 Is Anti-Apoptotic during Follicular Development from Preantral to Early Antral Stage. Mol Endocrinol. 2006 Oct;20(10):2456-68. Epub 2006 Jun 1..

Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish

Authors:
Oates AC, Ho RK
Citation:
Development 2002 Jun;129(12):2929-46
Epub:
Not Epub
Abstract:
We have examined the expression of a Hairy/E(spl)-related (Her) gene, her7, in the zebrafish and show that its expression in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oates AC, Ho RK. Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish. Development 2002 Jun;129(12):2929-46.

Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.

Authors:
Ochi H, Pearson BJ, Chuang PT, Hammerschmidt M, Westerfield M.
Citation:
Dev Biol. 2006 Sep 1;297(1):127-40. Epub 2006 May 6.
Epub:
Not Epub
Abstract:
Sharp borders between cells with different developmental fates are important for patterning of invertebrates, but are not well...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ochi H, Pearson BJ, Chuang PT, Hammerschmidt M, Westerfield M.. Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.. Dev Biol. 2006 Sep 1;297(1):127-40. Epub 2006 May 6..

HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development

Authors:
Norton WH, Ledin J, Grandel H, Neumann CJ
Citation:
Development. 2005 Nov;132(22):4963-73. Epub 2005 Oct 12
Epub:
Not Epub
Abstract:
Heparan sulphate proteoglycans (HSPGs) are known to be crucial for signalling by the secreted Wnt, Hedgehog, Bmp and Fgf...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Norton WH, Ledin J, Grandel H, Neumann CJ. HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development. Development. 2005 Nov;132(22):4963-73. Epub 2005 Oct 12.

Identification of nesfatin-1 as a satiety molecule in the hypothalamus

Authors:
Oh-I S, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, Eguchi H, Yamamoto M, Imaki T, Hashimoto K, Tsuchiya T, Monden T, Horiguchi K, Yamada M, Mori M
Citation:
Nature. 2006 Oct 12;443(7112):709-12. Epub 2006 Oct 1
Epub:
Not Epub
Abstract:
The brain hypothalamus contains certain secreted molecules that are important in regulating feeding behaviour. Here we show...
Delivery Method:
in vivo: intracerebroventricular injection
Organism or Cell Type:
Rat
Citation Extract:
Oh-I S, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, Eguchi H, Yamamoto M, Imaki T, Hashimoto K, Tsuchiya T, Monden T, Horiguchi K, Yamada M, Mori M. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature. 2006 Oct 12;443(7112):709-12. Epub 2006 Oct 1.

Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy

Authors:
O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, van den Heuvel LP, Fehrenbach H, Wiggins R, Goyal M, Zhou W, Wolf MT, Wise E, Helou J, Allen SJ, Murga-Zamalloa CA, Ashraf S, Chaki M, Heeringa S, Chernin G, Hoskins BE, Chaib H, Gleeson J, Kusakabe T, Suzuki T, Isaac RE, Quarmby LM, Tennant B, Fujioka H, Tuominen H, Hassinen I, Lohi H, van Houten JL, Rotig A, Sayer JA, Rolinski B, Freisinger P, Madhavan SM, Herzer M, Madignier F, Prokisch H, Nurnberg P, Jackson P, Khanna H, Katsanis N, Hildebrandt F
Citation:
J Clin Invest. 2010 Feb 22. pii: 40076. doi: 10.1172/JCI40076. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The autosomal recessive kidney disease nephronophthisis (NPHP) constitutes the most frequent genetic cause of terminal renal...
Organism or Cell Type:
zebrafish
Citation Extract:
O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, van den Heuvel LP, Fehrenbach H, Wiggins R, Goyal M, Zhou W, Wolf MT, Wise E, Helou J, Allen SJ, Murga-Zamalloa CA, Ashraf S, Chaki M, Heeringa S, Chernin G, Hoskins BE, Chaib H, Gleeson J, Kusakabe T, Suzuki T, Isaac RE, Quarmby LM, Tennant B, Fujioka H, Tuominen H, Hassinen I, Lohi H, van Houten JL, Rotig A, Sayer JA, Rolinski B, Freisinger P, Madhavan SM, Herzer M, Madignier F, Prokisch H, Nurnberg P, Jackson P, Khanna H, Katsanis N, Hildebrandt F. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. J Clin Invest. 2010 Feb 22. pii: 40076. doi: 10.1172/JCI40076. [Epub ahead of print].

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