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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development

Authors:
Yee NS, Gong W, Huang Y, Lorent K, Dolan AC, Maraia RJ, Pack M
Citation:
PLoS Biol. 2007 Nov;5(11):e312
Epub:
Not Epub
Abstract:
The role of RNA polymerase III (Pol III) in developing vertebrates has not been examined. Here, we identify a causative...
Organism or Cell Type:
zebrafish
Citation Extract:
Yee NS, Gong W, Huang Y, Lorent K, Dolan AC, Maraia RJ, Pack M. Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development. PLoS Biol. 2007 Nov;5(11):e312.

Mutation of the Bone Morphogenetic Protein GDF3 causes ocular and skeletal anomalies

Authors:
Ye M, Berry-Wynne KM, Asai-Coakwell M, Sundaresan P, Footz T, French CR, Abitbol M, Fleisch VC, Corbett N, Allison WT, Drummond G, Walter MA, Underhill TM, Waskiewicz AJ, Lehmann OJ
Citation:
Hum Mol Genet. 2009 Oct 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ocular mal-development results in heterogeneous and frequently visually disabling phenotypes that include coloboma and...
Organism or Cell Type:
zebrafish
Citation Extract:
Ye M, Berry-Wynne KM, Asai-Coakwell M, Sundaresan P, Footz T, French CR, Abitbol M, Fleisch VC, Corbett N, Allison WT, Drummond G, Walter MA, Underhill TM, Waskiewicz AJ, Lehmann OJ. Mutation of the Bone Morphogenetic Protein GDF3 causes ocular and skeletal anomalies. Hum Mol Genet. 2009 Oct 28. [Epub ahead of print].

Mutations in OTOGL, Encoding the Inner Ear Protein Otogelin-like, Cause Moderate Sensorineural Hearing Loss

Authors:
Yariz KO, Duman D, Seco CZ, Dallman J, Huang M, Peters TA, Sirmaci A, Lu N, Schraders M, Skromne I, Oostrik J, Diaz-Horta O, Young JI, Tokgoz-Yilmaz S, Konukseven O, Shahin H, Hetterschijt L, Kanaan M, Oonk AM, Edwards YJ, Li H, Atalay S, Blanton S, Desmidt AA, Liu XZ, Pennings RJ, Lu Z, Chen ZY, Kremer H, Tekin M
Citation:
Am J Hum Genet. 2012 Nov 2;91(5):872-82. doi: 10.1016/j.ajhg.2012.09.011
Epub:
Not Epub
Abstract:
Hereditary hearing loss is characterized by a high degree of genetic heterogeneity. Here we present OTOGL mutations, a...
Organism or Cell Type:
zebrafish
Citation Extract:
Yariz KO, Duman D, Seco CZ, Dallman J, Huang M, Peters TA, Sirmaci A, Lu N, Schraders M, Skromne I, Oostrik J, Diaz-Horta O, Young JI, Tokgoz-Yilmaz S, Konukseven O, Shahin H, Hetterschijt L, Kanaan M, Oonk AM, Edwards YJ, Li H, Atalay S, Blanton S, Desmidt AA, Liu XZ, Pennings RJ, Lu Z, Chen ZY, Kremer H, Tekin M . Mutations in OTOGL, Encoding the Inner Ear Protein Otogelin-like, Cause Moderate Sensorineural Hearing Loss. Am J Hum Genet. 2012 Nov 2;91(5):872-82. doi: 10.1016/j.ajhg.2012.09.011.

New regulators of vertebrate appendage regeneration

Authors:
Yin VP, Poss KD
Citation:
Curr Opin Genet Dev. 2008 Aug;18(4):381-6. Epub 2008 Aug 11
Epub:
Not Epub
Abstract:
Appendage regeneration is a complex and fascinating biological process exhibited in vertebrates by urodele amphibians and...
Organism or Cell Type:
zebrafish
Citation Extract:
Yin VP, Poss KD. New regulators of vertebrate appendage regeneration. Curr Opin Genet Dev. 2008 Aug;18(4):381-6. Epub 2008 Aug 11.

Optimizing exon skipping therapies for DMD

Authors:
Yokota T, Duddy W, Partridge T
Citation:
Acta Myol. 2007 Dec;26(3):179-84
Epub:
Not Epub
Abstract:
Exon skipping is one of the more promising therapeutic options for Duchenne Muscular Dystrophy (DMD). The idea is to use...
Citation Extract:
Yokota T, Duddy W, Partridge T. Optimizing exon skipping therapies for DMD. Acta Myol. 2007 Dec;26(3):179-84.

Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle program in zebrafish

Authors:
Yao Z, Farr III GH, Tapscott SJ, Maves L
Citation:
Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133921
Epub:
Not Epub
Abstract:
The basic helix–loop–helix factor Myod initiates skeletal muscle differentiation by directly and sequentially activating sets...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yao Z, Farr III GH, Tapscott SJ, Maves L. Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle program in zebrafish. Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133921 .

Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice

Authors:
Yin H, Saleh AF, Betts C, Camelliti P, Seow Y, Ashraf S, Arzumanov A, Hammond S, Merritt T, Gait MJ, Wood MJA
Citation:
Molecular Therapy. 2011 April 19;[Epub ahead of print] doi:10.1038/mt.2011.79
Epub:
Not Epub
Abstract:
Induced splice modulation of pre-mRNAs shows promise to correct aberrant disease transcripts and restore functional protein and...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Saleh AF, Betts C, Camelliti P, Seow Y, Ashraf S, Arzumanov A, Hammond S, Merritt T, Gait MJ, Wood MJA. Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice. Molecular Therapy. 2011 April 19;[Epub ahead of print] doi:10.1038/mt.2011.79.

Potential of oligonucleotide-mediated exon-skipping therapy for Duchenne muscular dystrophy

Authors:
Yokota T, Pistilli E, Duddy W, Nagaraju K
Citation:
Expert Opin Biol Ther. 2007 Jun;7(6):831-842
Epub:
Not Epub
Abstract:
Many of the mutations associated with Duchenne muscular dystrophy can potentially be rescued by exon-skipping therapy,...
Citation Extract:
Yokota T, Pistilli E, Duddy W, Nagaraju K. Potential of oligonucleotide-mediated exon-skipping therapy for Duchenne muscular dystrophy. Expert Opin Biol Ther. 2007 Jun;7(6):831-842.

Ptenb Mediates Gastrulation Cell Movements via Cdc42/AKT1 in Zebrafish

Authors:
Yeh CM, Liu YC, Chang CJ, Lai SL, Hsiao CD, Lee SJ
Citation:
PLoS ONE. 2011;6(4):e18702. doi:10.1371/journal.pone.0018702
Epub:
Not Epub
Abstract:
Phosphatidylinositol 3-kinase (PI3 kinase) mediates gastrulation cell migration in zebrafish via its regulation of PIP2/PIP3...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yeh CM, Liu YC, Chang CJ, Lai SL, Hsiao CD, Lee SJ. Ptenb Mediates Gastrulation Cell Movements via Cdc42/AKT1 in Zebrafish. PLoS ONE. 2011;6(4):e18702. doi:10.1371/journal.pone.0018702.

Reduced expression of vps11 causes less pigmentation in medaka, Oryzias latipes

Authors:
Yu JF, Fukamachi S, Mitani H, Hori H, Kanamori A
Citation:
Pigment Cell Res. 2006 Dec;19(6):628-34
Epub:
Not Epub
Abstract:
In this article, we describe the medaka mutant pale gray eyes (pge) that shows reduction of black, white, and silver...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Yu JF, Fukamachi S, Mitani H, Hori H, Kanamori A. Reduced expression of vps11 causes less pigmentation in medaka, Oryzias latipes. Pigment Cell Res. 2006 Dec;19(6):628-34.

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