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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

CPP-Directed Oligonucleotide Exon Skipping in Animal Models of Duchenne Muscular Dystrophy

Authors:
Yin H, Moulton H, Betts C, Wood M
Citation:
Methods Mol Biol. 2011;683:321-38
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (AOs) are effective splice switching agents and have potential as therapeutics via the exclusion or...
Delivery Method:
peptide-coupled
Citation Extract:
Yin H, Moulton H, Betts C, Wood M. CPP-Directed Oligonucleotide Exon Skipping in Animal Models of Duchenne Muscular Dystrophy. Methods Mol Biol. 2011;683:321-38.

Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells

Authors:
Yew KH, Hembree M, Prasadan K, Preuett B, McFall C, Benjes C, Crowley A, Sharp S, Tulachan S, Mehta S, Tei E, Gittes G
Citation:
J Biol Chem. 2005 Sep 16;280(37):32209-17. Epub 2005 Jul 14
Epub:
Not Epub
Abstract:
A key goal of cellular engineering is to manipulate progenitor cells to become beta-cells, allowing cell replacement therapy to...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
Cell culture: rat AR42J
Citation Extract:
Yew KH, Hembree M, Prasadan K, Preuett B, McFall C, Benjes C, Crowley A, Sharp S, Tulachan S, Mehta S, Tei E, Gittes G. Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells. J Biol Chem. 2005 Sep 16;280(37):32209-17. Epub 2005 Jul 14.

Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish

Authors:
Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A
Citation:
Dev Cell. 2010 Feb 16;18(2):226-36
Epub:
Not Epub
Abstract:
Cell polarity is crucial for directed migration. Here we show that phosphoinositide 3-kinase (PI(3)K) mediates neutrophil...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A. Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Dev Cell. 2010 Feb 16;18(2):226-36.

Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors

Authors:
Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, Zon LI, Fraenkel E, Cantor AB
Citation:
Mol Cell. 2012 Feb 10;45(3):330-43. doi: 10.1016/j.molcel.2011.11.032
Epub:
Not Epub
Abstract:
Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, Zon LI, Fraenkel E, Cantor AB. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell. 2012 Feb 10;45(3):330-43. doi: 10.1016/j.molcel.2011.11.032.

Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish

Authors:
Yoo SK, Freisinger CM, LeBert DC, Huttenlocher A
Citation:
J Cell Biol. 2012;[Epub ahead of print] doi:10.1083/jcb.201203154
Epub:
Not Epub
Abstract:
Tissue injury can lead to scar formation or tissue regeneration. How regenerative animals sense initial tissue injury and...
Organism or Cell Type:
zebrafish
Citation Extract:
Yoo SK, Freisinger CM, LeBert DC, Huttenlocher A. Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. J Cell Biol. 2012;[Epub ahead of print] doi:10.1083/jcb.201203154 .

Effects of light illumination and the expression of wee1 on tissue regeneration in adult zebrafish

Authors:
Ye Q, Chen D, Xi Y, Li J, Shao J, Li L
Citation:
Biochem Biophys Res Commun. 2012 Oct 10. pii: S0006-291X(12)01958-4. doi: 10.1016/j.bbrc.2012.10.021. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The zebrafish exhibits an enhanced capability of regenerating most of its adult tissues. In this study, we examine the roles of...
Delivery Method:
Injection
Organism or Cell Type:
zebrafish
Citation Extract:
Ye Q, Chen D, Xi Y, Li J, Shao J, Li L. Effects of light illumination and the expression of wee1 on tissue regeneration in adult zebrafish. Biochem Biophys Res Commun. 2012 Oct 10. pii: S0006-291X(12)01958-4. doi: 10.1016/j.bbrc.2012.10.021. [Epub ahead of print].

Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs

Authors:
Yokota T, Lu QL, Partridge T, Kobayashi M, Nakamura A, Takeda S, Hoffman E
Citation:
Ann Neurol. 2009 Jun;65(6):667-76. doi: 10.1002/ana.21627.
Epub:
Not Epub
Abstract:
OBJECTIVE: Duchenne muscular dystrophy (DMD) is caused by the inability to produce dystrophin protein at the myofiber membrane...
Delivery Method:
in vivo: injection
Organism or Cell Type:
Dog, beagle CXMD (DMD model)
Citation Extract:
Yokota T, Lu QL, Partridge T, Kobayashi M, Nakamura A, Takeda S, Hoffman E. Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs. Ann Neurol. 2009 Jun;65(6):667-76. doi: 10.1002/ana.21627..

Essential requirement for zebrafish anosmin-1a in the migration of the posterior lateral line primordium

Authors:
Yanicostas C, Ernest S, Dayraud C, Petit C, Soussi-Yanicostas N
Citation:
Dev Biol. 2008 Jun 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Kallmann syndrome (KS) is a human genetic disease that impairs both cell migration and axon elongation. The KAL-1 gene...
Organism or Cell Type:
zebrafish
Citation Extract:
Yanicostas C, Ernest S, Dayraud C, Petit C, Soussi-Yanicostas N. Essential requirement for zebrafish anosmin-1a in the migration of the posterior lateral line primordium. Dev Biol. 2008 Jun 13. [Epub ahead of print].

Exocrine pancreas development in zebrafish

Authors:
Yee NS, Lorent K, Pack M
Citation:
Dev Biol. 2005 Aug 1;284(1):84-101.
Epub:
Not Epub
Abstract:
Although many of the genes that regulate development of the endocrine pancreas have been identified, comparatively little is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yee NS, Lorent K, Pack M. Exocrine pancreas development in zebrafish. Dev Biol. 2005 Aug 1;284(1):84-101..

Exogenous control of mammalian gene expression through modulation of RNA self-cleavage

Authors:
Yen L, Svendsen J, Lee JS, Gray JT, Magnier M, Baba T, D'Amato RJ, Mulligan RC
Citation:
Nature. 2004 Sep 23;431(7007):471-6
Epub:
Not Epub
Abstract:
Recent studies on the control of specific metabolic pathways in bacteria have documented the existence of entirely RNA-based...
Delivery Method:
in vitro: TNT
Organism or Cell Type:
not applicable
Citation Extract:
Yen L, Svendsen J, Lee JS, Gray JT, Magnier M, Baba T, D'Amato RJ, Mulligan RC. Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature. 2004 Sep 23;431(7007):471-6.

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