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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Extensive and Prolonged Restoration of Dystrophin Expression with Vivo-Morpholino-Mediated Multiple Exon Skipping in Dystrophic Dogs
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Citation:
Nucleic Acid Ther. 2012 Oct;22(5):306-15. doi: 10.1089/nat.2012.0368. Epub 2012 Aug 13. Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a severe and the most prevalent form of muscular dystrophy, characterized by rapid... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Dog, beagle CXMD (DMD model) Citation Extract: Yokota T, Nakamura A, Nagata T, Saito T, Kobayashi M, Aoki Y, Echigoya Y, Partridge T, Hoffman EP, Takeda S. Extensive and Prolonged Restoration of Dystrophin Expression with Vivo-Morpholino-Mediated Multiple Exon Skipping in Dystrophic Dogs. Nucleic Acid Ther. 2012 Oct;22(5):306-15. doi: 10.1089/nat.2012.0368. Epub 2012 Aug 13.. |
Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish
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Citation:
Genes Dev. 2008 Mar 15;22(6):728-33 Epub:
Not Epub Abstract:
Appendage regeneration is defined by rapid changes in gene expression that achieve dramatic developmental effects, suggesting... Delivery Method:
Microinjection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Yin VP, Thomson JM, Thummel R, Hyde DR, Hammond SM, Poss KD. Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish. Genes Dev. 2008 Mar 15;22(6):728-33. |
Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO
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Citation:
Mol Ther. 2010 Aug 10. [Epub ahead of print] Epub:
Not Epub Abstract:
Splice modulation using antisense oligonucleotides (AOs) has been shown to yield targeted exon exclusion to restore the open... Delivery Method:
i.v. injection Organism or Cell Type:
mice, mdx Citation Extract: Yin H, Moulton HM, Betts C, Merritt T, Seow Y, Ashraf S, Wang Q, Boutilier J, Wood MJ. Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO. Mol Ther. 2010 Aug 10. [Epub ahead of print]. |
Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult
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Citation:
Biochem Pharmacol. 2007 Mar 15;73(6):782-92. Epub 2006 Dec 3 Epub:
Not Epub Abstract:
Hepatocellular carcinoma is a very common malignancy and is chemoresistant to currently available chemotherapeutic agents.... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human hepatocyte Hep3B Citation Extract: Yeh TC, Chiang PC, Li TK, Hsu JL, Lin CJ, Wang SW, Peng CY, Guh JH. Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult. Biochem Pharmacol. 2007 Mar 15;73(6):782-92. Epub 2006 Dec 3. |
Gα(13) is closely related to hematopoiesis in zebrafish
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Citation:
Mol Biol Rep. 2010 Nov 27. [Epub ahead of print] Epub:
Not Epub Abstract:
Heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) function as signal transducers and control many... Organism or Cell Type:
zebrafish Citation Extract: Ye D, Yang Q, Li Y, Huang X, Hu J, Qian S, Tan Z, Song P. Gα(13) is closely related to hematopoiesis in zebrafish. Mol Biol Rep. 2010 Nov 27. [Epub ahead of print]. |
Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish
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Citation:
Dev Cell. 2010 Jun 15;18(6):973-84 Epub:
Not Epub Abstract:
Extracellular matrix (ECM) remodeling is critical for organogenesis, yet its molecular regulation is poorly understood. In... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Yin C, Kikuchi K, Hochgreb T, Poss KD, Stainier DY. Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. Dev Cell. 2010 Jun 15;18(6):973-84. |
HEB and E2A function as SMAD/FOXH1 cofactors
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Citation:
Genes Dev. 2011 Aug 1;25(15):1654-61 Epub:
Not Epub Abstract:
Nodal signaling, mediated through SMAD transcription factors, is necessary for pluripotency maintenance and endoderm commitment... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Yoon SJ, Wills AE, Chuong E, Gupta R, Baker JC. HEB and E2A function as SMAD/FOXH1 cofactors. Genes Dev. 2011 Aug 1;25(15):1654-61. |
Hsp90 Selectively Modulates Phenotype in Vertebrate Development
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Citation:
PLoS Genet. 2007 Mar 30;3(3):e43 [Epub ahead of print] Epub:
Not Epub Abstract:
Compromised heat shock protein 90 (Hsp90) function reveals cryptic phenotypes in flies and plants. These observations were... Organism or Cell Type:
zebrafish Citation Extract: Yeyati PL, Bancewicz RM, Maule J, van Heyningen V. Hsp90 Selectively Modulates Phenotype in Vertebrate Development. PLoS Genet. 2007 Mar 30;3(3):e43 [Epub ahead of print]. |
Human Cytomegalovirus Induces TLR4 Signaling Components in Monocytes Altering TIRAP, TRAM and Downstream Interferon-Beta and TNF-Alpha Expression
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Citation:
PLoS ONE. 2012;7(9):e44500. doi:10.1371/journal.pone.0044500 Epub:
Not Epub Abstract:
Using TLR pathways, primary human cytomegalovirus (HCMV) induces innate responses including the production of inflammatory... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: THP-1 cells Citation Extract: Yew KH, Carpenter C, Duncan RS, Harrison CJ. Human Cytomegalovirus Induces TLR4 Signaling Components in Monocytes Altering TIRAP, TRAM and Downstream Interferon-Beta and TNF-Alpha Expression. PLoS ONE. 2012;7(9):e44500. doi:10.1371/journal.pone.0044500. |
Identification of CCAAT/Enhancer-binding Proteins as Exchange Protein Activated by cAMP-activated Transcription Factors That Mediate the Induction of the SOCS-3 Gene
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Citation:
J Biol Chem. 2008 Mar 14;283(11):6843-53. Epub 2008 Jan 14 Epub:
Not Epub Abstract:
The prototypical second messenger cyclic AMP is a key regulator of immune and inflammatory responses. Its ability to inhibit... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HUVEC Citation Extract: Yarwood SJ, Borland G, Sands WA, Palmer TM. Identification of CCAAT/Enhancer-binding Proteins as Exchange Protein Activated by cAMP-activated Transcription Factors That Mediate the Induction of the SOCS-3 Gene. J Biol Chem. 2008 Mar 14;283(11):6843-53. Epub 2008 Jan 14. |