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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice
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Citation:
Hum Mol Genet. 2009 Aug 18. [Epub ahead of print] Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene that abolish the synthesis of dystrophin protein.... Delivery Method:
peptide-coupled Organism or Cell Type:
mice, mdx Citation Extract: Yin H, Moulton HM, Betts C, Seow Y, Boutilier J, Iverson PL, Wood MJ. A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice. Hum Mol Genet. 2009 Aug 18. [Epub ahead of print]. |
A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor
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Citation:
Development. 2003 May;130(10):2199-212. Erratum in: Development. 2004 Aug;13(15):3821 Epub:
Not Epub Abstract:
Convergent extension behaviour is critical for the formation of the vertebrate body axis. In Xenopus, components of the Wnt... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J. A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor. Development. 2003 May;130(10):2199-212. Erratum in: Development. 2004 Aug;13(15):3821. |
A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground
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Citation:
Arch Neurol. 2009 Jan;66(1):32-8 Epub:
Not Epub Abstract:
Antisense oligonucleotides are short nucleic acid sequences designed for use as small-molecule drugs. They recognize and bind... Citation Extract: Yokota T, Takeda S, Lu QL, Partridge TA, Nakamura A, Hoffman EP. A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground. Arch Neurol. 2009 Jan;66(1):32-8. |
A Zebrafish Forebrain-Specific Zinc Finger Gene Can Induce Ectopic dlx2 and dlx6 Expression
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Citation:
Dev Biol 2001 Mar 1;231(1):138-148 Epub:
Not Epub Abstract:
Identification of the earliest forebrain-specific markers should facilitate the elucidation of molecular events underlying... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang Z, Liu N, Lin S. A Zebrafish Forebrain-Specific Zinc Finger Gene Can Induce Ectopic dlx2 and dlx6 Expression. Dev Biol 2001 Mar 1;231(1):138-148. |
AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression
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Citation:
Development. 2008 Jan;135(2):401-10 Epub:
Not Epub Abstract:
AML1-ETO is one of the most common chromosomal translocation products associated with acute myelogenous leukemia (AML).... Organism or Cell Type:
zebrafish Citation Extract: Yeh JR, Munson KM, Chao YL, Peterson QP, Macrae CA, Peterson RT. AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. Development. 2008 Jan;135(2):401-10. |
Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells
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Citation:
J Neurosci. 2002 Nov 15;22(22):9764-70 Epub:
Not Epub Abstract:
Insoluble fibrils of amyloid-beta peptide (Abeta) are the major component of senile and vascular plaques found in the brains of... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: mouse cerebral endothelial cells Citation Extract: Yin KJ, Lee JM, Chen SD, Xu J, Hsu CY. Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells. J Neurosci. 2002 Nov 15;22(22):9764-70. |
Anaplastic Lymphoma Kinase Is Required for Neurogenesis in the Developing Central Nervous System of Zebrafish
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Citation:
PLoS ONE. 2013;8(5):e63757. doi:10.1371/journal.pone.0063757 Epub:
Not Epub Abstract:
Anaplastic Lymphoma Kinase (ALK) was initially discovered as an oncogene in human lymphoma and other cancers, including... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Yao S, Cheng M, Zhang Q, Wasik M, Kelsh R, Winkler C. Anaplastic Lymphoma Kinase Is Required for Neurogenesis in the Developing Central Nervous System of Zebrafish. PLoS ONE. 2013;8(5):e63757. doi:10.1371/journal.pone.0063757. |
Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy
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Citation:
Methods Mol Biol. 2011;709:299-312 Epub:
Not Epub Abstract:
Exon skipping is currently one of the most promising molecular therapies for Duchenne muscular -dystrophy (DMD). We have... Delivery Method:
Injection Organism or Cell Type:
Dog, beagle CXMD (DMD model) Citation Extract: Yokota T, Hoffman E, Takeda S. Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy. Methods Mol Biol. 2011;709:299-312. |
Antisense targeting of CXXC finger protein 1 inhibits genomic cytosine methylation and primitive hematopoiesis in zebrafish
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Citation:
J Biol Chem. 2006 Oct 4; [Epub ahead of print] Epub:
Not Epub Abstract:
CXXC Finger Protein 1 (CFP1) binds to unmethylated CpG dinucleotides, and is a component of the Set1 histone methyltransferase... Organism or Cell Type:
zebrafish Citation Extract: Young SR, Mumaw C, Marrs JA, Skalnik DG. Antisense targeting of CXXC finger protein 1 inhibits genomic cytosine methylation and primitive hematopoiesis in zebrafish. J Biol Chem. 2006 Oct 4; [Epub ahead of print]. |
ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells
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Citation:
Stroke. 2002 Oct;33(10):2471-7 Epub:
Not Epub Abstract:
BACKGROUND AND PURPOSE: Cells lacking the ATM (ataxia telangectasia mutated) gene are hypersensitive to DNA damage caused by a... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: mouse cerebral endothelial cells Citation Extract: Yin KJ, Chen SD, Lee JM, Xu J, Hsu CY. ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells. Stroke. 2002 Oct;33(10):2471-7. |