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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: analysis of stellate cell entry into the developing liver

Authors:
Yin C, Evason KJ, Maher JJ, Stainier DY
Citation:
Hepatology. 2012 Nov;56(5):1958-70. doi: 10.1002/hep.25757. Epub 2012 Oct 14
Epub:
Not Epub
Abstract:
Hepatic stellate cells (HSCs) are liver-specific mesenchymal cells that play vital roles in liver development and injury. Our...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yin C, Evason KJ, Maher JJ, Stainier DY. The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: analysis of stellate cell entry into the developing liver. Hepatology. 2012 Nov;56(5):1958-70. doi: 10.1002/hep.25757. Epub 2012 Oct 14.

Gene miles-apart is required for formation of otic vesicle and hair cells in zebrafish

Authors:
Hu ZY, Zhang QY, Qin W, Tong JW, Zhao Q, Han Y, Meng J, Zhang JP
Citation:
Cell Death Dis. 2013 Oct 31;4:e900. doi: 10.1038/cddis.2013.432
Epub:
Not Epub
Abstract:
Hearing loss is a serious burden to physical and mental health worldwide. Aberrant development and damage of hearing organs are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu ZY, Zhang QY, Qin W, Tong JW, Zhao Q, Han Y, Meng J, Zhang JP. Gene miles-apart is required for formation of otic vesicle and hair cells in zebrafish. Cell Death Dis. 2013 Oct 31;4:e900. doi: 10.1038/cddis.2013.432.

Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signaling and RhoA effector function

Authors:
Xu X, Shuen WH, Chen C, Goudevenou K, Jones P, Sablitzky F
Citation:
Dev Biol. 2013 Oct 28. doi:pii: S0012-1606(13)00575-7. 10.1016/j.ydbio.2013.10.020. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Swap70 functions as a guanine nucleotide exchange factor for Rac and RhoA regulating F-actin cytoskeletal rearrangements and...
Citation Extract:
Xu X, Shuen WH, Chen C, Goudevenou K, Jones P, Sablitzky F. Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signaling and RhoA effector function. Dev Biol. 2013 Oct 28. doi:pii: S0012-1606(13)00575-7. 10.1016/j.ydbio.2013.10.020. [Epub ahead of print].

Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor Beta 1a (TGFß1a)

Authors:
Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimaki A, Ramet M, Parikka M, Hytonen VP, Nykter M, Pesu M
Citation:
J Biol Chem. 2013 Dec 20;288(51):36610-23. doi: 10.1074/jbc.M113.453183. Epub 2013 Oct 31
Epub:
Yes
Abstract:
Proprotein convertase subtilisin/kexin (PCSK) enzymes convert proproteins into bioactive end-products. While other PCSK enzymes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimaki A, Ramet M, Parikka M, Hytonen VP, Nykter M, Pesu M. Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor Beta 1a (TGFß1a). J Biol Chem. 2013 Dec 20;288(51):36610-23. doi: 10.1074/jbc.M113.453183. Epub 2013 Oct 31.

Fgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development

Authors:
Larbuisson A, Dalcq J, Martial JA, Muller M
Citation:
Differentiation. 2013 Oct 28. doi:pii: S0301-4681(13)00063-7. 10.1016/j.diff.2013.07.006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cranial cartilage derives mainly from cranial neural crest cells and its formation requires fibroblast growth factor (Fgf)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Larbuisson A, Dalcq J, Martial JA, Muller M. Fgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development. Differentiation. 2013 Oct 28. doi:pii: S0301-4681(13)00063-7. 10.1016/j.diff.2013.07.006. [Epub ahead of print].

Enhancing the Function of CD34+ Cells by Targeting Plasminogen Activator Inhibitor-1

Authors:
Hazra S, Stepps V, Bhatwadekar AD, Caballero S, Boulton ME, Higgins PJ, Nikonova EV, Pepine CJ, Thut C, Finney EM, Stone DJ, Bartelmez SH, Grant MB
Citation:
PLoS ONE. 2013;8(11):e79067. doi:10.1371/journal.pone.0079067
Epub:
Not Epub
Abstract:
Previously, we showed that transient inhibition of TGF- β1 resulted in correction of key aspects of diabetes-induced CD34+ cell...
Organism or Cell Type:
Cultured CD34+ cells
Citation Extract:
Hazra S, Stepps V, Bhatwadekar AD, Caballero S, Boulton ME, Higgins PJ, Nikonova EV, Pepine CJ, Thut C, Finney EM, Stone DJ, Bartelmez SH, Grant MB. Enhancing the Function of CD34+ Cells by Targeting Plasminogen Activator Inhibitor-1. PLoS ONE. 2013;8(11):e79067. doi:10.1371/journal.pone.0079067.

Essential roles of LEM-domain protein MAN1 during organogenesis in Xenopus laevis and overlapping functions of emerin

Authors:
Reil M, Dabauvalle M-C
Citation:
Eur J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.008
Epub:
Not Epub
Abstract:
Mutations in nuclear envelope proteins are linked to an increasing number of human diseases, called envelopathies. Mutations in...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Reil M, Dabauvalle M-C. Essential roles of LEM-domain protein MAN1 during organogenesis in Xenopus laevis and overlapping functions of emerin. Eur J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.008.

Neurotrophic factor NT-3 displays a non-canonical cell guidance signalling function for cephalic neural crest cells

Authors:
Zanin JP, Battiato NL, Rovasio RA
Citation:
Euro J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.006
Epub:
Not Epub
Abstract:
Chemotactic cell migration is triggered by extracellular concentration gradients of molecules segregated by target fields....
Delivery Method:
electroporation
Organism or Cell Type:
Chick
Citation Extract:
Zanin JP, Battiato NL, Rovasio RA. Neurotrophic factor NT-3 displays a non-canonical cell guidance signalling function for cephalic neural crest cells. Euro J Cell Biol. 2013;[Epub ahead of print] doi:10.1016/j.ejcb.2013.10.006.

Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron

Authors:
Echeverria GV, Cooper TA
Citation:
Nucl Acids Res. 2013;[Epub ahead of print] doi:10.1093/nar/gkt1020
Epub:
Not Epub
Abstract:
Alternative splicing regulates developmentally and tissue-specific gene expression programs, disruption of which have been...
Organism or Cell Type:
Cell-free system
Citation Extract:
Echeverria GV, Cooper TA. Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron. Nucl Acids Res. 2013;[Epub ahead of print] doi:10.1093/nar/gkt1020.

Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish

Authors:
Winata CL, Kondrychyn I, Kumar V, Srinivasan KG, Orlov Y, Ravishankar A, Prabhakar S, Stanton LW, Korzh V, Mathavan S
Citation:
PLoS Genet. 2013;9(10):e1003852. doi:10.1371/journal.pgen.1003852
Epub:
Not Epub
Abstract:
Zic3 regulates early embryonic patterning in vertebrates. Loss of Zic3 function is known to disrupt gastrulation, left-right...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Winata CL, Kondrychyn I, Kumar V, Srinivasan KG, Orlov Y, Ravishankar A, Prabhakar S, Stanton LW, Korzh V, Mathavan S. Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish. PLoS Genet. 2013;9(10):e1003852. doi:10.1371/journal.pgen.1003852.

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