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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression

Authors:
Rösel-Hillgärtner TD, Hung L-H, Khrameeva E, Le Querrec P, Gelfand MS, Bindereif A
Citation:
PLoS Genet. 2013;9(10):e1003856. doi:10.1371/journal.pgen.1003856
Epub:
Not Epub
Abstract:
The U1 small nuclear ribonucleoprotein (snRNP)-specific U1C protein participates in 5' splice site recognition and...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Rösel-Hillgärtner TD, Hung L-H, Khrameeva E, Le Querrec P, Gelfand MS, Bindereif A. A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression. PLoS Genet. 2013;9(10):e1003856. doi:10.1371/journal.pgen.1003856 .

Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction

Authors:
Charvet B, Guiraud A, Malbouyres M, Zwolanek D, Guillon E, Bretaud S, Monnot C, Schulze J, Bader HL, Allard B, Koch M, Ruggiero F
Citation:
2013;[Epub ahead of print] doi:10.1242/dev.096024
Epub:
Not Epub
Abstract:
The myotendinous junction (MTJ) is the major site of force transfer in skeletal muscle, and defects in its structure correlate...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Charvet B, Guiraud A, Malbouyres M, Zwolanek D, Guillon E, Bretaud S, Monnot C, Schulze J, Bader HL, Allard B, Koch M, Ruggiero F. Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction. 2013;[Epub ahead of print] doi:10.1242/dev.096024 .

Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy

Authors:
Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U
Citation:
J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8
Epub:
Not Epub
Abstract:
In recent years, oligonucleotide-based molecules have been intensely used to modulate gene expression. All these molecules...
Delivery Method:
peptide
Organism or Cell Type:
cell culture
Citation Extract:
Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8.

eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation

Authors:
Yogev O, Williams VC, Hinits Y, Hughes SM
Citation:
PLoS Biol. 2013;11(10):e1001679. doi:10.1371/journal.pbio.1001679
Epub:
Not Epub
Abstract:
Muscle fiber size is activity-dependent and clinically important in ageing, bed-rest, and cachexia, where muscle weakening...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Yogev O, Williams VC, Hinits Y, Hughes SM. eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation. PLoS Biol. 2013;11(10):e1001679. doi:10.1371/journal.pbio.1001679 .

a2-Chimaerin Regulates a Key Axon Guidance Transition during Development of the Oculomotor Projection

Authors:
Clark C, Austen O, Poparic I, Guthrie S
Citation:
J Neurosci. 2013;33(42):16540-51. doi:10.1523/JNEUROSCI.1869-13.2013
Epub:
Not Epub
Abstract:
The ocular motor system consists of three nerves which innervate six muscles to control eye movements. In humans, defective...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Clark C, Austen O, Poparic I, Guthrie S. a2-Chimaerin Regulates a Key Axon Guidance Transition during Development of the Oculomotor Projection. J Neurosci. 2013;33(42):16540-51. doi:10.1523/JNEUROSCI.1869-13.2013 .

Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent

Authors:
Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Mühlfeld C, Engel FB
Citation:
Proc Natl Acad Sci U S A. 2013;110(2):16898-903. doi:10.1073/pnas.1304837110
Epub:
Not Epub
Abstract:
Despite their abundance and multiple functions in a variety of organ systems, the function and signaling mechanisms of adhesion...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Mühlfeld C, Engel FB. Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. Proc Natl Acad Sci U S A. 2013;110(2):16898-903. doi:10.1073/pnas.1304837110 .

Autonomy in specification of primordial germ cells and their passive translocation in the sea urchin. Development

Authors:
Yajima M, Wessel GM
Citation:
2012 Oct;139(20):3786-94
Epub:
Not Epub
Abstract:
The process of germ line determination involves many conserved genes, yet is highly variable. Echinoderms are positioned at the...
Delivery Method:
microinjection
Organism or Cell Type:
Sea urchin Strongylocentrotus purpuratus
Citation Extract:
Yajima M, Wessel GM. Autonomy in specification of primordial germ cells and their passive translocation in the sea urchin. Development. 2012 Oct;139(20):3786-94.

tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches

Authors:
Thi Thu HN, Haw Tien SF, Loh SL, Bok Yan JS, Korzh V
Citation:
PLoS ONE. 2013;8(10):e77171. doi:10.1371/journal.pone.0077171
Epub:
Not Epub
Abstract:
Tbx2 is a member of the T-box family of transcription factors essential for embryo- and organogenesis. A deficiency in the...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Thi Thu HN, Haw Tien SF, Loh SL, Bok Yan JS, Korzh V. tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches. PLoS ONE. 2013;8(10):e77171. doi:10.1371/journal.pone.0077171 .

NumbL is essential for Xenopus primary neurogenesis

Authors:
Nieber F, Hedderich M, Jahn O, Pieler T, Henningfeld KA
Citation:
BMC Dev Biol. 2013 Oct 14;13(1):36. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Members of the vertebrate Numb family of cell fate determinants serve multiple functions throughout early...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nieber F, Hedderich M, Jahn O, Pieler T, Henningfeld KA. NumbL is essential for Xenopus primary neurogenesis. BMC Dev Biol. 2013 Oct 14;13(1):36. [Epub ahead of print].

Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish

Authors:
Ryan S, Willer J, Marjoram L, Bagwell J, Mankiewicz J, Leshchiner I, Goessling W, Bagnat M, Katsanis N
Citation:
Development. 2013;140:4445-4451. doi:10.1242/dev.101170
Epub:
Not Epub
Abstract:
Forward genetic approaches in zebrafish have provided invaluable information about developmental processes. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Ryan S, Willer J, Marjoram L, Bagwell J, Mankiewicz J, Leshchiner I, Goessling W, Bagnat M, Katsanis N. Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish. Development. 2013;140:4445-4451. doi:10.1242/dev.101170 .

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