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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings

Authors:
Zdebik AA, Mahmood F, Stanescu HC, Kleta R, Bockenhauer D, Russell C
Citation:
PLoS ONE. 2013;8(11):e79765. doi:10.1371/journal.pone.0079765
Epub:
Not Epub
Abstract:
We aimed to develop and validate a reliable method for stable long-term recordings of EEG activity in zebrafish, which is less...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0079765
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zdebik AA, Mahmood F, Stanescu HC, Kleta R, Bockenhauer D, Russell C. Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings. PLoS ONE. 2013;8(11):e79765. doi:10.1371/journal.pone.0079765.

Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region

Authors:
Ellery PER, Maroney SA, Martinez ND, Wickens MP, Mast AE
Citation:
Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):187-95. doi: 10.1161/ATVBAHA.113.302660. Epub 2013 Nov 14.
Epub:
Yes
Abstract:
Objective: Tissue factor pathway inhibitor (TFPI) blocks the initiation of coagulation by inhibiting TF-activated factor VII,...
Link:
http://atvb.ahajournals.org/content/early/2013/11/14/ATVBAHA.113.302660.abstract
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: MDA-MB-231 cells
Citation Extract:
Ellery PER, Maroney SA, Martinez ND, Wickens MP, Mast AE. Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region. Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):187-95. doi: 10.1161/ATVBAHA.113.302660. Epub 2013 Nov 14..

Oligonucleotide therapeutics in cancer

Authors:
Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R
Citation:
Cancer Treat Res. 2013;158:213-33. doi: 10.1007/978-3-642-31659-3_9
Epub:
Not Epub
Abstract:
Alterations in pre-mRNA splicing can have profound effects on gene expression and lead to cellular transformation....
Link:
http://link.springer.com/chapter/10.1007%2F978-3-642-31659-3_9
Citation Extract:
Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Oligonucleotide therapeutics in cancer. Cancer Treat Res. 2013;158:213-33. doi: 10.1007/978-3-642-31659-3_9.

Podocalyxin regulates pronephric glomerular development in zebrafish

Authors:
Ichimura K, Powell R, Nakamura T, Kurihara H, Sakai T, Obara T
Citation:
Physiol Rep. 2013 Aug;1(3). doi:pii: e00074
Epub:
Not Epub
Abstract:
Vertebrate glomerular podocytes possess a highly sialylated transmembrane glycoprotein, Podocalyxin. In mammals, the sialic...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/phy2.74/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ichimura K, Powell R, Nakamura T, Kurihara H, Sakai T, Obara T. Podocalyxin regulates pronephric glomerular development in zebrafish. Physiol Rep. 2013 Aug;1(3). doi:pii: e00074.

Piwi regulates Vasa accumulation during embryogenesis in the sea urchin

Authors:
Yajima M, Gustafson EA, Song JL, Wessel GM
Citation:
Dev Dyn. 2013 Nov 12. doi: 10.1002/dvdy.24096. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Piwi proteins are essential for germ line development, stem cell maintenance, and more recently found to function...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24096/abstract
Organism or Cell Type:
Sea urchin: Strongylocentrotus purpuratus
Citation Extract:
Yajima M, Gustafson EA, Song JL, Wessel GM. Piwi regulates Vasa accumulation during embryogenesis in the sea urchin. Dev Dyn. 2013 Nov 12. doi: 10.1002/dvdy.24096. [Epub ahead of print].

A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis

Authors:
Kotkamp K, Mössner R, Allen A, Onichtchouk D, Driever W
Citation:
Dev Biol. 2013 Nov 5. doi:pii: S0012-1606(13)00580-0. 10.1016/j.ydbio.2013.10.025. [Epub ahead of print]
Epub:
Yes
Abstract:
In mammalian ES cells, the transcription factors Klf4 and Klf2 contribute to maintenance of pluripotency and self-renewal and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160613005800
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kotkamp K, Mössner R, Allen A, Onichtchouk D, Driever W. A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis. Dev Biol. 2013 Nov 5. doi:pii: S0012-1606(13)00580-0. 10.1016/j.ydbio.2013.10.025. [Epub ahead of print].

Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome

Authors:
Albers CA, Cvejic A, Favier R, Bouwmans EE, Alessi MC, Bertone P, Jordan G, Kettleborough RN, Kiddle G, Kostadima M, Read RJ, Sipos B, Sivapalaratnam S, Smethurst PA, Stephens J, Voss K, Nurden A, Rendon A, Nurden P, Ouwehand WH
Citation:
Nat Genet. 2011 Jul 17;43(8):735-7. doi: 10.1038/ng.885
Epub:
Yes
Abstract:
Gray platelet syndrome (GPS) is a predominantly recessive platelet disorder that is characterized by mild thrombocytopenia with...
Link:
http://www.nature.com/ng/journal/v43/n8/full/ng.885.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Albers CA, Cvejic A, Favier R, Bouwmans EE, Alessi MC, Bertone P, Jordan G, Kettleborough RN, Kiddle G, Kostadima M, Read RJ, Sipos B, Sivapalaratnam S, Smethurst PA, Stephens J, Voss K, Nurden A, Rendon A, Nurden P, Ouwehand WH. Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome. Nat Genet. 2011 Jul 17;43(8):735-7. doi: 10.1038/ng.885.

A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis

Authors:
Paik EJ, Mahony S, White RM, Price EN, DiBiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI
Citation:
Stem Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.stemcr.2013.10.001
Epub:
Yes
Abstract:
Deletion of caudal/cdx genes alters hox gene expression and causes defects in posterior tissues and hematopoiesis. Yet, the...
Link:
https://www.cell.com/stem-cell-reports/abstract/S2213-6711(13)00095-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paik EJ, Mahony S, White RM, Price EN, DiBiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI. A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis. Stem Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.stemcr.2013.10.001.

Genetic control of single lumen formation in the zebrafish gut

Authors:
Bagnat M, Cheung ID, Mostov KE, Stainier DY
Citation:
Nat Cell Biol. 2007 Aug;9(8):954-60. Epub 2007 Jul 15
Epub:
Not Epub
Abstract:
Most organs consist of networks of interconnected tubes that serve as conduits to transport fluid and cells and act as...
Link:
http://www.nature.com/ncb/journal/v9/n8/full/ncb1621.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bagnat M, Cheung ID, Mostov KE, Stainier DY. Genetic control of single lumen formation in the zebrafish gut. Nat Cell Biol. 2007 Aug;9(8):954-60. Epub 2007 Jul 15.

Emilin3 is required for notochord sheath integrity and interacts with Scube2 to regulate notochord-derived Hedgehog signals

Authors:
Corallo D, Schiavinato A, Trapani V, Moro E, Argenton F, Bonaldo P
Citation:
Development. 2013 Nov;140(22):4594-601. doi: 10.1242/dev.094078. Epub 2013 Oct 16
Epub:
Not Epub
Abstract:
The notochord is a transient and essential structure that provides both mechanical and signaling cues to the developing...
Link:
http://dev.biologists.org/content/140/22/4594.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Corallo D, Schiavinato A, Trapani V, Moro E, Argenton F, Bonaldo P. Emilin3 is required for notochord sheath integrity and interacts with Scube2 to regulate notochord-derived Hedgehog signals. Development. 2013 Nov;140(22):4594-601. doi: 10.1242/dev.094078. Epub 2013 Oct 16.

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