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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish
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Citation:
Exp Neurol. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.expneurol.2013.11.012 Epub:
Yes Abstract:
Demyelinating diseases include multiple sclerosis, which is a neurodegenerative disease characterized by immune attacks on the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yin W, Hu B. Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish. Exp Neurol. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.expneurol.2013.11.012. |
A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality
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Citation:
Nat Commun. 2013 Nov 11;4:2754. doi: 10.1038/ncomms3754 Epub:
Yes Abstract:
Breaking left-right symmetry in bilateria is a major event during embryo development that is required for asymmetric organ... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Noël ES, Verhoeven M, Lagendijk AK, Tessadori F, Smith K, Choorapoikayil S, den Hertog J, Bakkers J. A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality. Nat Commun. 2013 Nov 11;4:2754. doi: 10.1038/ncomms3754. |
Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges
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Citation:
Nat Struct Mol Biol. 2013 Nov 10. doi: 10.1038/nsmb.2699. [Epub ahead of print] Epub:
Yes Abstract:
Alternative splicing (AS) enables programmed diversity of gene expression across tissues and development. We show here that... Delivery Method:
Vivo-Morpholino in vivo, Endo-Porter in culture Organism or Cell Type:
mouse, cell culture: HS578T cells Citation Extract: Lovci MT, Ghanem D, Marr H, Arnold J, Gee S, Parra M, Liang TY, Stark TJ, Gehman LT, Hoon S, Massirer KB, Pratt GA, Black DL, Gray JW, Conboy JG, Yeo GW. Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges. Nat Struct Mol Biol. 2013 Nov 10. doi: 10.1038/nsmb.2699. [Epub ahead of print]. |
Directional tissue migration through a self-generated chemokine gradient
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Citation:
Nature. 2013 Nov 14;503(7475):285-9. doi: 10.1038/nature12635. Epub 2013 Sep 25 Epub:
Not Epub Abstract:
The directed migration of cell collectives is a driving force of embryogenesis. The predominant view in the field is that cells... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Donà E, Barry JD, Valentin G, Quirin C, Khmelinskii A, Kunze A, Durdu S, Newton LR, Fernandez-Minan A, Huber W, Knop M, Gilmour D. Directional tissue migration through a self-generated chemokine gradient. Nature. 2013 Nov 14;503(7475):285-9. doi: 10.1038/nature12635. Epub 2013 Sep 25. |
The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality
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Citation:
Nature. 2013 Nov 13. doi: 10.1038/nature12723. [Epub ahead of print] Epub:
Yes Abstract:
Heterotaxy is a disorder of left-right body patterning, or laterality, that is associated with major congenital heart disease.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Boskovski MT, Yuan S, Pedersen NB, Goth CK, Makova S, Clausen H, Brueckner M, Khokha MK. The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality. Nature. 2013 Nov 13. doi: 10.1038/nature12723. [Epub ahead of print]. |
Inhibitory signalling to the Arp2/3 complex steers cell migration
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Citation:
Nature. 2013 Nov 14;503(7475):281-4. doi: 10.1038/nature12611. Epub 2013 Oct 16 Epub:
Not Epub Abstract:
Cell migration requires the generation of branched actin networks that power the protrusion of the plasma membrane in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dang I, Gorelik R, Sousa-Blin C, Derivery E, Guérin C, Linkner J, Nemethova M, Dumortier JG, Giger FA, Chipysheva TA, Ermilova VD, Vacher S, Campanacci V, Herrada I, Planson AG, Fetics S, Henriot V, David V, Oguievetskaia K, Lakisic G, Pierre F, Steffen A, Boyreau A, Peyriéras N, Rottner K, Zinn-Justin S, Cherfils J, Bièche I, Alexandrova AY, David NB, Small JV, Faix J, Blanchoin L, Gautreau A. Inhibitory signalling to the Arp2/3 complex steers cell migration. Nature. 2013 Nov 14;503(7475):281-4. doi: 10.1038/nature12611. Epub 2013 Oct 16. |
Knockdown of Pex11β reveals its pivotal role in regulating peroxisomal genes, numbers, and ROS levels in Xenopus laevis A6 cells
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Citation:
In Vitro Cell Dev Biol Anim. 2013 Nov 14. [Epub ahead of print] Epub:
Yes Abstract:
Peroxisomes are organelles that are ubiquitously found in all eukaryotic cells. Enzymes within their lumen are responsible for... Organism or Cell Type:
cell culture: Xenopus laevis A6 cells Citation Extract: Fox MA, Nieuwesteeg MA, Willson JA, Cepeda M, Damjanovski S. Knockdown of Pex11β reveals its pivotal role in regulating peroxisomal genes, numbers, and ROS levels in Xenopus laevis A6 cells. In Vitro Cell Dev Biol Anim. 2013 Nov 14. [Epub ahead of print]. |
Morpholino treatment improves muscle function and pathology of Pitx1 transgenic mice
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Citation:
Mol Ther. 2013 Nov 14. doi: 10.1038/mt.2013.263. [Epub ahead of print] Epub:
Yes Abstract:
Paired-like homeodomain transcription factor 1 (PITX1) was proposed to be part of the disease mechanisms of facioscapulohumeral... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Pandey SN, Lee YC, Yokota T, Chen YW. Morpholino treatment improves muscle function and pathology of Pitx1 transgenic mice. Mol Ther. 2013 Nov 14. doi: 10.1038/mt.2013.263. [Epub ahead of print]. |
The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis
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Citation:
PLoS Genet. 2013;9(10):e1003822. doi:10.1371/journal.pgen.1003822 Epub:
Not Epub Abstract:
Dorsoventral patterning of the embryonic axis relies upon the mutual antagonism of competing signaling pathways to establish a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kapp LD, Abrams EW, Marlow FL, Mullins MC. The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis. PLoS Genet. 2013;9(10):e1003822. doi:10.1371/journal.pgen.1003822. |
Par6b Regulates the Dynamics of Apicobasal Polarity during Development of the Stratified Xenopus Epidermis
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Citation:
PLoS ONE. 2013;8(10): e76854. doi:10.1371/journal.pone.0076854 Epub:
Not Epub Abstract:
During early vertebrate development, epithelial cells establish and maintain apicobasal polarity, failure of which can cause... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Wang S, Cha S-W, Zorn AM, Wylie C. Par6b Regulates the Dynamics of Apicobasal Polarity during Development of the Stratified Xenopus Epidermis. PLoS ONE. 2013;8(10): e76854. doi:10.1371/journal.pone.0076854. |