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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish

Authors:
Li L, Chen D, Li J, Wang X, Wang N, Xu C, Wang QK
Citation:
Blood. 2013 Nov 25. [Epub ahead of print]
Epub:
Yes
Abstract:
The hemangioblast is a multipotential progenitor, which is derived from the mesoderm and can further differentiate into...
Link:
http://bloodjournal.hematologylibrary.org/content/early/2013/11/25/blood-2013-07-514612.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Chen D, Li J, Wang X, Wang N, Xu C, Wang QK. Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish. Blood. 2013 Nov 25. [Epub ahead of print].

Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo

Authors:
Plouhinec JL, Zakin L, Moriyama Y, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2013 Nov 27. [Epub ahead of print]
Epub:
Yes
Abstract:
The vertebrate body plan follows stereotypical dorsal-ventral (D-V) tissue differentiation controlled by bone morphogenetic...
Link:
http://www.pnas.org/content/early/2013/11/27/1319745110.abstract
Organism or Cell Type:
Xenopus
Citation Extract:
Plouhinec JL, Zakin L, Moriyama Y, De Robertis EM. Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proc Natl Acad Sci U S A. 2013 Nov 27. [Epub ahead of print].

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1

Authors:
Bräutigam L, Jensen LDE, Poschmann G, Nyström S, Bannenberg S, Dreij K, Lepka K, Prozorovski T, Montano SJ, Aktas O, Uhlén P, Stühler K, Cao Y, Holmgren A, Berndt C
Citation:
PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1313753110
Epub:
Not Epub
Abstract:
Embryonic development depends on complex and precisely orchestrated signaling pathways including specific reduction/oxidation...
Link:
http://www.pnas.org/content/early/2013/11/22/1313753110.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bräutigam L, Jensen LDE, Poschmann G, Nyström S, Bannenberg S, Dreij K, Lepka K, Prozorovski T, Montano SJ, Aktas O, Uhlén P, Stühler K, Cao Y, Holmgren A, Berndt C. Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1. PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1313753110.

Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy

Authors:
Zaharieva IT, Calissano M, Scoto M, Preston M, Cirak S, Feng L, Collins J, Kole R, Guglieri M, Straub V, Bushby K, Ferlini A, Morgan JE, Muntoni F
Citation:
PLoS ONE. 2013;8(11):e80263. doi:10.1371/journal.pone.0080263
Epub:
Not Epub
Abstract:
Duchenne muscular Dystrophy (DMD) is an inherited disease caused by mutations in the dystrophin gene that disrupt the open...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0080263
Delivery Method:
i.v. infusion
Organism or Cell Type:
Human - clinical trials
Citation Extract:
Zaharieva IT, Calissano M, Scoto M, Preston M, Cirak S, Feng L, Collins J, Kole R, Guglieri M, Straub V, Bushby K, Ferlini A, Morgan JE, Muntoni F. Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy. PLoS ONE. 2013;8(11):e80263. doi:10.1371/journal.pone.0080263.

A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis

Authors:
Bilandžija H, Ma L, Parkhurst A, Jeffery WR
Citation:
PLoS ONE. 2013;8(11):e80823. doi:10.1371/journal.pone.0080823
Epub:
Not Epub
Abstract:
Albinism, the loss of melanin pigmentation, has evolved in a diverse variety of cave animals but the responsible evolutionary...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0080823
Delivery Method:
microinjection
Organism or Cell Type:
Astyanax mexicanus
Citation Extract:
Bilandžija H, Ma L, Parkhurst A, Jeffery WR. A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis. PLoS ONE. 2013;8(11):e80823. doi:10.1371/journal.pone.0080823.

Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure

Authors:
Chu C-W, Gerstenzang E, Ossipova O, Sokol SY
Citation:
PLoS ONE. 2013;8(11):e81854. doi:10.1371/journal.pone.0081854
Epub:
Not Epub
Abstract:
Apical constriction is an essential cell behavior during neural tube closure, but its underlying mechanisms are not fully...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0081854
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chu C-W, Gerstenzang E, Ossipova O, Sokol SY. Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure. PLoS ONE. 2013;8(11):e81854. doi:10.1371/journal.pone.0081854.

ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption

Authors:
Ashraf S, Gee HY, Woerner S, Xie LX, Vega-Warner V, Lovric S, Fang H, Song X, Cattran DC, Avila-Casado C, Paterson AD, Nitschké P, Bole-Feysot C, Cochat P, Esteve-Rudd J, Haberberger B, Allen SJ, Zhou W, Airik R, Otto EA, Barua M, Al-Hamed MH, Kari JA, Evans J, Bierzynska A, Saleem MA, Böckenhauer D, Kleta R, El Desoky S, Hacihamdioglu DO, Gok F, Washburn J, Wiggins RC, Choi M, Lifton RP, Levy S, Han Z, Salviati L, Prokisch H, Williams DS, Pollak M, Clarke CF, Pei Y, Antignac C, Hildebrandt F
Citation:
J Clin Invest. 2013 Nov 25. doi:pii: 69000. 10.1172/JCI69000. [Epub ahead of print]
Epub:
Yes
Abstract:
Identification of single-gene causes of steroid-resistant nephrotic syndrome (SRNS) has furthered the understanding of the...
Link:
http://www.jci.org/articles/view/69000
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ashraf S, Gee HY, Woerner S, Xie LX, Vega-Warner V, Lovric S, Fang H, Song X, Cattran DC, Avila-Casado C, Paterson AD, Nitschké P, Bole-Feysot C, Cochat P, Esteve-Rudd J, Haberberger B, Allen SJ, Zhou W, Airik R, Otto EA, Barua M, Al-Hamed MH, Kari JA, Evans J, Bierzynska A, Saleem MA, Böckenhauer D, Kleta R, El Desoky S, Hacihamdioglu DO, Gok F, Washburn J, Wiggins RC, Choi M, Lifton RP, Levy S, Han Z, Salviati L, Prokisch H, Williams DS, Pollak M, Clarke CF, Pei Y, Antignac C, Hildebrandt F. ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J Clin Invest. 2013 Nov 25. doi:pii: 69000. 10.1172/JCI69000. [Epub ahead of print].

Calcium binding is essential for plastin3 function in Smn-deficient motor neurons

Authors:
Lyon AN, Pineda RH, Hao LT, Kudryashova E, Kudryashov DS, Beattie CE
Citation:
Hum Mol Genet. 2013 Nov 23. [Epub ahead of print]
Epub:
Yes
Abstract:
The actin binding and bundling protein, plastin 3 (PLS3), was identified as a protective modifier of spinal muscular atrophy (...
Link:
http://hmg.oxfordjournals.org/content/early/2013/11/22/hmg.ddt595.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lyon AN, Pineda RH, Hao LT, Kudryashova E, Kudryashov DS, Beattie CE. Calcium binding is essential for plastin3 function in Smn-deficient motor neurons. Hum Mol Genet. 2013 Nov 23. [Epub ahead of print].

Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation

Authors:
Cox JA, LaMora A, Johnson SL, Voigt MA
Citation:
Int J Dev Neurosci. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.ijdevneu.2013.11.003
Epub:
Not Epub
Abstract:
In zebrafish, cranial sensory circuits form by 4 days post-fertilization. We used a forward genetic screen to identify genes...
Link:
http://www.sciencedirect.com/science/article/pii/S0736574813001688
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cox JA, LaMora A, Johnson SL, Voigt MA. Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation. Int J Dev Neurosci. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.ijdevneu.2013.11.003.

Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms

Authors:
Matsuzawa R, Fujiwara T, Nemoto K, Fukushima T, Yamaguchi S, Akagawa K, Hori Y
Citation:
Neurosci Lett. 2013;[Epub ahead of print] doi:10.1016/j.neulet.2013.11.017
Epub:
Yes
Abstract:
Pregabalin is widely used as an analgesic for the treatment of neuropathic pain. In the present experiments using mouse spinal...
Link:
http://www.sciencedirect.com/science/article/pii/S0304394013010173
Delivery Method:
intrathecal injection
Organism or Cell Type:
mouse
Citation Extract:
Matsuzawa R, Fujiwara T, Nemoto K, Fukushima T, Yamaguchi S, Akagawa K, Hori Y. Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms. Neurosci Lett. 2013;[Epub ahead of print] doi:10.1016/j.neulet.2013.11.017.

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