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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio.

Authors:
Edie S, Zaghloul NA, Leitch CC, Klinedinst DK, Lebron J, Thole JF, McCallion AS, Katsanis N, Reeves RH
Citation:
G3 (Bethesda). 2018 May 14. pii: g3.200144.2018. doi: 10.1534/g3.118.200144. [Epub ahead of print]
Epub:
Yes
Abstract:
Trisomy for human chromosome 21 (Hsa21) results in Down syndrome (DS), one of the most genetically complex conditions...
Link:
http://www.g3journal.org/content/early/2018/05/14/g3.118.200144.long
Organism or Cell Type:
zebrafish
Citation Extract:
Edie S, Zaghloul NA, Leitch CC, Klinedinst DK, Lebron J, Thole JF, McCallion AS, Katsanis N, Reeves RH. Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio. . G3 (Bethesda). 2018 May 14. pii: g3.200144.2018. doi: 10.1534/g3.118.200144. [Epub ahead of print] .

Role of calcium-sensing receptor in mechanotransducer-channel-mediated Ca2+ influx in hair cells of zebrafish larvae

Authors:
Lin L-Y, Yeh Y-H, Hung G-Y, Lin C-H, Hwang P-P, Horng J-L
Citation:
Front Physiol. 2018;[Epub] doi:10.3389/fphys.2018.00649
Epub:
Not Epub
Abstract:
The calcium-sensing receptor (CaSR) is an extracellular Ca2+ sensor that plays a critical role in maintaining Ca2+ homeostasis...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2018.00649/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Lin L-Y, Yeh Y-H, Hung G-Y, Lin C-H, Hwang P-P, Horng J-L. Role of calcium-sensing receptor in mechanotransducer-channel-mediated Ca2+ influx in hair cells of zebrafish larvae. Front Physiol. 2018;[Epub] doi:10.3389/fphys.2018.00649 .

Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132

Authors:
Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI
Citation:
Proc Natl Acad Sci U S A. 2018 Aug 23. pii: 201806077. doi: 10.1073/pnas.1806077115. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Epoxyeicosatrienoic acids (EETs) are lipid-derived signaling molecules with cardioprotective and vasodilatory actions. We...
Link:
http://www.pnas.org/content/115/37/9252
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proc Natl Acad Sci U S A. 2018 Aug 23. pii: 201806077. doi: 10.1073/pnas.1806077115. [Epub ahead of print].

Multiple functions for the catenin family member plakoglobin in cadherin-dependent adhesion, fibronectin matrix assembly and Xenopus gastrulation movements

Authors:
Hirsh GD, Dzamba BJ, Sonavane PR, Shook DR, Allen CM, DeSimone DW
Citation:
bioRxiv. 2018. doi:10.1101/318774
Epub:
Not Epub
Abstract:
Shaping an embryo requires tissue-scale cell rearrangements known as morphogenetic events. These force-dependent processes...
Link:
https://www.biorxiv.org/content/early/2018/05/09/318774
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hirsh GD, Dzamba BJ, Sonavane PR, Shook DR, Allen CM, DeSimone DW. Multiple functions for the catenin family member plakoglobin in cadherin-dependent adhesion, fibronectin matrix assembly and Xenopus gastrulation movements. bioRxiv. 2018. doi:10.1101/318774.

Integrin and ligand-independent PDGFr signaling synergistically contribute to directional migration of Xenopus mesendoderm

Authors:
Richardson CM, Dzamba BJ, Sonavane PR, DeSimone DW
Citation:
bioRxiv. 2018. doi:10.1101/318824
Epub:
Not Epub
Abstract:
Both PDGF signaling and adhesion to fibronectin (FN) matrix have been implicated in the directional collective migration of...
Link:
https://www.biorxiv.org/content/early/2018/05/09/318824
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Richardson CM, Dzamba BJ, Sonavane PR, DeSimone DW. Integrin and ligand-independent PDGFr signaling synergistically contribute to directional migration of Xenopus mesendoderm. bioRxiv. 2018. doi:10.1101/318824 .

Frequency and synchrony of actomyosin oscillation during PCP-dependent convergent extension

Authors:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB
Citation:
bioRxiv. 2018. doi:10.1101/316745
Epub:
Not Epub
Abstract:
Oscillatory actomyosin flows play a key role in single cell migration and in collective cell movements that shape invertebrates...
Link:
https://www.biorxiv.org/content/early/2018/05/08/316745
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shindo A, Inoue Y, Kinoshita M, Wallingford JB. Frequency and synchrony of actomyosin oscillation during PCP-dependent convergent extension. bioRxiv. 2018. doi:10.1101/316745.

The N-terminal domain of gastrulation brain homeobox 2 (Gbx2) is required for iridophore specification in zebrafish

Authors:
Hozumi S, Shirai M, Wang J, Aoki S, Kikuchi Y
Citation:
Biochem Biophys Res Commun. 2018 May 19. pii: S0006-291X(18)31197-5. doi: 10.1016/j.bbrc.2018.05.128. [Epub ahead of print]
Epub:
Yes
Abstract:
Although body color pattern formation by pigment cells plays critical roles in animals, pigment cell specification has not yet...
Link:
https://www.ncbi.nlm.nih.gov/pubmed/29787751
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hozumi S, Shirai M, Wang J, Aoki S, Kikuchi Y. The N-terminal domain of gastrulation brain homeobox 2 (Gbx2) is required for iridophore specification in zebrafish. Biochem Biophys Res Commun. 2018 May 19. pii: S0006-291X(18)31197-5. doi: 10.1016/j.bbrc.2018.05.128. [Epub ahead of print].

β-Catenin-dependent mechanotransduction dates back to the common ancestor of Cnidaria and Bilateria

Authors:
Pukhlyakova E, Aman AJ, Elsayad K, Technau U
Citation:
Proc Natl Acad Sci U S A. 2018 May 21. pii: 201713682. doi: 10.1073/pnas.1713682115. [Epub ahead of print]
Epub:
Yes
Abstract:
Although the genetic regulation of cellular differentiation processes is well established, recent studies have revealed the...
Link:
http://www.pnas.org/content/early/2018/05/16/1713682115
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Pukhlyakova E, Aman AJ, Elsayad K, Technau U. β-Catenin-dependent mechanotransduction dates back to the common ancestor of Cnidaria and Bilateria. Proc Natl Acad Sci U S A. 2018 May 21. pii: 201713682. doi: 10.1073/pnas.1713682115. [Epub ahead of print].

Heart enhancers with deeply conserved regulatory activity are established early in development

Authors:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD
Citation:
Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z
Epub:
Not Epub
Abstract:
During the phylotypic period, embryos from different genera show similar gene expression patterns, implying common regulatory...
Link:
https://www.nature.com/articles/s41467-018-07451-z
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan X, Song M, Devine P, Bruneau BG, Scott IC, Wilson MD. Heart enhancers with deeply conserved regulatory activity are established early in development. Nat Comm. 2018;9:4977. doi:10.1038/s41467-018-07451-z.

Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish

Authors:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S
Citation:
Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May
Epub:
Not Epub
Abstract:
Objective: DEPDC5 was identified as a major genetic cause of focal epilepsy with deleterious mutations found in a wide range of...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/acn3.542
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Calbiac H, Dabacan A, Marsan E, Tostivint H, Devienne G, Ishida S, Leguern E, Baulac S, Muresan RC, Kabashi E, Ciura S. Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish. Ann Clin Transl Neurol. 2018 Apr 6;5(5):510-523. doi: 10.1002/acn3.542. eCollection 2018 May.

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