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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Effective Synthesis of 5-Iodo Derivatives of Pyrimidine Morpholino Nucleosides

Authors:
Vohtancev IP, Sherstyuk YV, Silnikov VN, Abramova TV
Citation:
Org Prep Proc Int. 2018;50(3):332-42. doi:10.1080/00304948.2018.1462063
Epub:
Not Epub
Abstract:
No abstract available.
Link:
https://www.tandfonline.com/doi/full/10.1080/00304948.2018.1462063
Citation Extract:
Vohtancev IP, Sherstyuk YV, Silnikov VN, Abramova TV. Effective Synthesis of 5-Iodo Derivatives of Pyrimidine Morpholino Nucleosides. Org Prep Proc Int. 2018;50(3):332-42. doi:10.1080/00304948.2018.1462063.

Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation

Authors:
Houssin NS, Bharathan NK, Turner SD, Dickinson AJ
Citation:
Dev Dyn. 2017 Feb;246(2):100-115. doi: 10.1002/dvdy.24470. Epub 2016 Dec 29
Epub:
Not Epub
Abstract:
BACKGROUND: The buccopharyngeal membrane is a thin layer of cells covering the embryonic mouth. The perforation of this...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/dvdy.24470
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Houssin NS, Bharathan NK, Turner SD, Dickinson AJ. Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation. Dev Dyn. 2017 Feb;246(2):100-115. doi: 10.1002/dvdy.24470. Epub 2016 Dec 29.

Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening

Authors:
Shimo T, Tachibana K, Obika S
Citation:
PLoS One. 2018 May 16;13(5):e0197373. doi: 10.1371/journal.pone.0197373. eCollection 2018
Epub:
Not Epub
Abstract:
Splice-switching oligonucleotides (SSOs) that can modulate RNA splicing are used for the treatment of many genetic disorders....
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197373#pone.0197373.s006
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: RD
Citation Extract:
Shimo T, Tachibana K, Obika S. Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening. PLoS One. 2018 May 16;13(5):e0197373. doi: 10.1371/journal.pone.0197373. eCollection 2018.

Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain

Authors:
Than-Trong E, Ortica-Gatti S, Mella S, Nepal C, Alunni A, Bally-Cuif L
Citation:
Development. 2018 May 15;145(10). pii: dev161034. doi: 10.1242/dev.161034
Epub:
Not Epub
Abstract:
Neural stem cells (NSCs) in the adult vertebrate brain are found in a quiescent state and can preserve long-lasting progenitor...
Link:
http://dev.biologists.org/content/145/10/dev161034
Delivery Method:
intracerebroventricular injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Than-Trong E, Ortica-Gatti S, Mella S, Nepal C, Alunni A, Bally-Cuif L. Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain. Development. 2018 May 15;145(10). pii: dev161034. doi: 10.1242/dev.161034.

Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry

Authors:
Juan T, Géminard C, Coutelis JB, Cerezo D, Polès S, Noselli S, Fürthauer M
Citation:
Nat Commun. 2018 May 16;9(1):1942. doi: 10.1038/s41467-018-04284-8
Epub:
Not Epub
Abstract:
The establishment of left-right (LR) asymmetry is fundamental to animal development, but the identification of a unifying...
Link:
https://www.nature.com/articles/s41467-018-04284-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Juan T, Géminard C, Coutelis JB, Cerezo D, Polès S, Noselli S, Fürthauer M. Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry. Nat Commun. 2018 May 16;9(1):1942. doi: 10.1038/s41467-018-04284-8.

Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/β-Catenin activity

Authors:
Liu J-X, Xu Q-H, Yu XD, Zhang T, Xie XW, Ouyang G
Citation:
Int J Biol Sci. 2018;14(7):705-16. doi:10.7150/ijbs.18997
Epub:
Not Epub
Abstract:
During early vertebrate embryogenesis, maternal Wnt/β-catenin signaling is thought to locally initiate expression of dorsal-...
Link:
http://www.ijbs.com/v14p0705.htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J-X, Xu Q-H, Yu XD, Zhang T, Xie XW, Ouyang G. Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/β-Catenin activity. Int J Biol Sci. 2018;14(7):705-16. doi:10.7150/ijbs.18997.

Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice

Authors:
Guo J, Zhang T, Guo Y, Sun T, Li H, Zhang X, Yin H, Cao G, Yin Y, Wang H, Shi L, Guo X, Sha J, Eppig JJ, Su YQ
Citation:
Proc Natl Acad Sci U S A. 2018 May 21. pii: 201800352. doi: 10.1073/pnas.1800352115. [Epub ahead of print]
Epub:
Yes
Abstract:
MTOR (mechanistic target of rapamycin) is a widely recognized integrator of signals and pathways key for cellular metabolism,...
Link:
http://www.pnas.org/content/early/2018/05/15/1800352115
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Guo J, Zhang T, Guo Y, Sun T, Li H, Zhang X, Yin H, Cao G, Yin Y, Wang H, Shi L, Guo X, Sha J, Eppig JJ, Su YQ. Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice. Proc Natl Acad Sci U S A. 2018 May 21. pii: 201800352. doi: 10.1073/pnas.1800352115. [Epub ahead of print].

Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish

Authors:
Guerra A, Germano RF, Stone O, Arnaout R, Guenther S, Ahuja S, Uribe V, Vanhollebeke B, Stainier DY, Reischauer S
Citation:
Elife. 2018 May 15;7. pii: e32833. doi: 10.7554/eLife.32833
Epub:
Not Epub
Abstract:
The ultimate formation of a four-chambered heart allowing the separation of the pulmonary and systemic circuits was key for the...
Link:
https://elifesciences.org/articles/32833
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guerra A, Germano RF, Stone O, Arnaout R, Guenther S, Ahuja S, Uribe V, Vanhollebeke B, Stainier DY, Reischauer S. Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish. Elife. 2018 May 15;7. pii: e32833. doi: 10.7554/eLife.32833.

Retinoic acid induced expression of Hnf1β and Fzd4 is required for pancreas development in Xenopus laevis

Authors:
Gere MB, Pommerenke C, Lingner T, Pieler T
Citation:
Development. 2018 May 16. pii: dev.161372. doi: 10.1242/dev.161372. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid (RA) is required for pancreas specification in Xenopus and other vertebrates. However, the gene network that is...
Link:
http://dev.biologists.org/content/early/2018/05/15/dev.161372
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gere MB, Pommerenke C, Lingner T, Pieler T. Retinoic acid induced expression of Hnf1β and Fzd4 is required for pancreas development in Xenopus laevis. Development. 2018 May 16. pii: dev.161372. doi: 10.1242/dev.161372. [Epub ahead of print].

Extracellular Vesicle-delivered Bone Morphogenetic Proteins: A novel paracrine mechanism during embryonic development

Authors:
Draebing T, Heigwer J, Juergensen L, Katus HA, Hassel D
Citation:
bioRxiv. 2018. doi:10.1101/321356
Epub:
Not Epub
Abstract:
Morphogens including Wnt, Hedgehog and BMP proteins are essential during embryonic development and early induction of organ...
Link:
https://www.biorxiv.org/content/early/2018/05/13/321356
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Draebing T, Heigwer J, Juergensen L, Katus HA, Hassel D. Extracellular Vesicle-delivered Bone Morphogenetic Proteins: A novel paracrine mechanism during embryonic development. bioRxiv. 2018. doi:10.1101/321356.

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